AI Summary & Key Takeaways
AI InsightLaboratory findings revealed that the hemoglobin concentration was 17.1 g/dl, the hematocrit was 48.4%, the WBC count was 28 500 /mm<sup>3</sup>, the platelet count was 674000/ mm<sup>3</sup>.
📌 3 Key Takeaways
Abstract
Various factors were shown about the etiology of cerebral venous thrombosis and hypercoagulopathy plays a very important role among these factors. In this study, we described a 34 year-old woman who had nausea, vomiting and gradually increasing headache for a month. Neurological evaluation was normal except for bilateral grade IV papiloedema. Neuroradiological investigation demonstrated complete thrombosis of the superior sagittal sinus, confluent sinium, transvers and sigmoid sinuses bilaterally. Laboratory findings revealed that the hemoglobin concentration was 17.1 g/dl, the hematocrit was 48.4%, the WBC count was 28 500 /mm<sup>3</sup>, the platelet count was 674000/ mm<sup>3</sup>. Bone marrow biopsy was performed and essential thrombocythemia was diagnosed. The patient has been maintained on anticoagulant and ribonucleotide reductase inhibitor. In the literature disseminated venous thrombosis as seen in our patient was rarely reported. Hematological diseases, endocrinological disorders and anatomical variations are reported as etiological factors.
Özet
Serebral venöz tromboz etyolojisinde birçok neden bulunmakla birlikte, hiperkoagulabilite önemli rol oynamaktadır. Bu çalışmada son bir aydır giderek artan başağrısı, bulantı, kusma nedeni ile servisimize yatan, daha önce hiçbir yakınması olmayan 34 yaşındaki bayan hasta bildirilmiştir. Hastanın yapılan nörolojik muayenesinde bilateral grade IV papil ödem mevcut olup, nöroradyolojik inceleme sonucunda yaygın (superior sagittal sinüs, konfluen sinium, her iki transvers ve sigmoid sinüsler) serebral venöz tromboz tespit edilmiştir. Tam kan sayımında Hb 17.1 g/dl, Hct % 48.4, Lökosit 28 500 /mm 3 , Plt 674 000 /mm 3 bulunması nedeni ile yapılan kemik iliği incelemesinde hastaya esansiyel trombositemi tanısı konmuş olup, antikoagulan tedavi yanısıra ribonükleotid redüktaz inhibitörü de tedaviye eklenmiştir. Literatürde olgumuzda olduğu gibi yaygın serebral venöz tromboz olguları nadiren bildirilmiş olup, bazı hematolojik hastalıkların, endokrin bozuklukların ve anatomik varyasyonların etyolojide yer alabileceği ifade edilmiştir.