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Journals / Kırıkkale Üniversitesi Tıp Fakültesi Dergisi / 2021 / Cilt: 23 - Sayı: 3

EVALUATION OF HEPATIC VASCULAR FLOW ALTERATIONS IN OBESE CHILDREN WITH AND WITHOUT NON-ALCOHOLIC FATTY LIVER DISEASE

Non-Alkolik Yağlı Karaciğer Hastalığı Olan ve Olmayan Obez Çocuklarda Hepatik Vasküler Akım Değişikliklerinin Değerlendirilmesi

Hüseyin AYDIN
Ayşe AYDINOĞLU
Müge ATAR
Mustafa AKÇAM
Özgür PİRGON
Pages
607–616
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Objective: To evaluate hepatic vascular flow alterations using Doppler ultrasound in obese children with and without non-alcoholic fatty liver disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To evaluate hepatic vascular flow alterations using Doppler ultrasound in obese children with and without non-alcoholic fatty liver disease.
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Key Findings & Data:Objective: To evaluate hepatic vascular flow alterations using Doppler ultrasound in obese children with and without non-alcoholic fatty liver disease.
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Conclusion & Impact:Objective: To evaluate hepatic vascular flow alterations using Doppler ultrasound in obese children with and without non-alcoholic fatty liver disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Non alkolik yağlı karaciğer hastalığı · portal ven · hepatik arter

Abstract

Objective: To evaluate hepatic vascular flow alterations using Doppler ultrasound in obese children with and without non-alcoholic fatty liver disease.

Özet

Amaç: Non-alkolik yağlı karaciğer hastalığı olan ve olmayan obez çocuklarda hepatik vasküler akım değişikliklerini Doppler ultrason ile değerlendirmektir.

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Cite This Article

AYDIN, H., AYDINOĞLU, A., ATAR, M., AKÇAM, M., PİRGON, Ö. (2021). EVALUATION OF HEPATIC VASCULAR FLOW ALTERATIONS IN OBESE CHILDREN WITH AND WITHOUT NON-ALCOHOLIC FATTY LIVER DISEASE. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, Cilt: 23 - Sayı: 3, 607–616. https://ajindex.com/articles/408896

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References (11)

  1. Friedman SL, Neuschwander-Tetri BA, Rinella M, Sanyal AJ. Mechanisms of NAFLD development and therapeutic strategies. Nat Med. 2018;24(7):908-22
  2. Akcam M, Boyaci A, Pirgon O, Koroglu M, Dundar BN. Importance of the liver ultrasound scores in pubertal obese children with nonalcoholic fatty liver disease. Clin Imaging. 2013;37(3):504-8
  3. Mosca A, Panera N, Crudele A, Alisi A. Noninvasive diagnostic tools for pediatric NAFLD: where are we now? Expert Rev Gastroenterol Hepatol. 2020:14(11):1035-46
  4. Buzzetti E, Pinzani M, Tsochatzis EA. The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD). Metabolism. 2016;65(8):1038-48
  5. Francque S, Laleman W, Verbeke L, Van Steenkiste C, Casteleyn C, Kwanten W et al. Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture. Lab Investig. 2012;92(10):1428-39
  6. Francque S, Verrijken A, Mertens I, Hubens G, Van Marck E, Pelckmans P et al. Noncirrhotic human nonalcoholic fatty liver disease induces portal hypertension in relation to the histological degree of steatosis. Eur J Gastroenterol Hepatol. 2010;22(12):1449-57. 7. van der Graaff D, Kwanten WJ, Francque SM. The potential role of vascular alterations and subsequent impaired liver blood flow and hepatic hypoxia in the pathophysiology of non-alcoholic steatohepatitis. Med Hypotheses. 2019;122:188-97
  7. Lautt WW. Regulatory processes interacting to maintain hepatic blood flow constancy: vascular compliance, hepatic arterial buffer response, hepatorenal reflex, liver regeneration, escape from vasoconstriction. Hepatol Res. 2007;37(11):891-903
  8. Balasubramanian P, Boopathy V, Govindasamy E, Venkatesh BP. Assessment of portal venous and hepatic artery haemodynamic variation in non-alcoholic fatty liver disease (NAFLD) patients. J Clin Diagnostic Res. 2016;10(8):TC07
  9. Soresi M, Giannitrapani L, Noto D, Terranova A, Campagna ME, Cefalù AB et al. Effects of steatosis on hepatic hemodynamics in patients with metabolic syndrome. Ultrasound Med Biol. 2015;41(6):1545-52
  10. Hizli S, Koçyigit A, Arslan N, Tuncel SA, Demircioglu F, Cakmakçi H et al. Hepatic artery resistance in children with obesity and fatty liver. Indian J Pediatr. 2010;77(4):407-11
  11. Mohammadi A, Ghasemi-Rad M, Zahedi H, Toldi G, Alinia T. Effect of severity of steatosis as assessed ultrasonographically on hepatic vascular indices in non-alcoholic fatty liver disease. Med Ultrason