AI Summary & Key Takeaways
AI InsightThe overall rate of mortality frombleeding did not significantly change between the two periods.Conclusion: Over the 23 years studied, the causes of NVUGB changed, probably because the population was increasingly elderly population and because of the use of anticoagulants and better therapeutic approaches to chronic duodenal ulcers.
📌 3 Key Takeaways
Özet
Background/Aims: This study aimed to compare the causes of nonvariceal upper gastrointestinal bleeding (NVUGB), demographics, riskfactors, and outcomes of patients during two periods between 1993 and 2016 in a tertiary health-care center in Turkey.Materials and Methods: We compared the causes of NVUGB and clinical outcomes in 421 patients hospitalized between January 1993and December 1995 with those of 231 patients with NVUGB hospitalized between January 2015 and September 2016. We also compared epidemiological characteristics, risk factors, and the rates of endoscopic hemostatic procedures.Results: We observed significant increases in patients’ mean age, in the percentage of patients with comorbid conditions, and in thepercentage of patients who received direct-acting oral anticoagulants before bleeding. We also observed a statistically nonsignificantincrease in the diagnoses of gastric ulcer, along with a significant concordant decrease in diagnoses of duodenal ulcer as a cause ofbleeding. The use of emergency surgical hemostasis decreased among cases of peptic ulcer bleeding. The overall rate of mortality frombleeding did not significantly change between the two periods.Conclusion: Over the 23 years studied, the causes of NVUGB changed, probably because the population was increasingly elderly population and because of the use of anticoagulants and better therapeutic approaches to chronic duodenal ulcers. The use of emergencysurgical hemostasis reduced, but mortality rate did not significantly change between the two specific periods.