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Journals / Turkish Journal of Gastroenterology / 2020 / Cilt: 31 - Sayı: 11

Delta MELD as a predictor of early outcome in adult-to-adult living donor liver transplantation

Şencan ACAR
Murat AKYILDIZ
Ahmet GÜRAKAR
Yaman TOKAT
Murat DAYANGAÇ
Pages
782–789
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Responders vs. non-responders were compared according to etiology, demographics, and survival.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/Aims: An increased post-operative mortality risk has been reported among patients who undergo living donor liver transplantation (LDLT) with higher model for end-stage liver disease (MELD) scores.
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Key Findings & Data:In this study, we investigated the effect of MELD score reduction on post-operative outcomes in patients with a high MELD (≥20) score by pre-transplant management.
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Conclusion & Impact:Responders vs. non-responders were compared according to etiology, demographics, and survival.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Background/Aims: An increased post-operative mortality risk has been reported among patients who undergo living donor liver transplantation (LDLT) with higher model for end-stage liver disease (MELD) scores. In this study, we investigated the effect of MELD score reduction on post-operative outcomes in patients with a high MELD (≥20) score by pre-transplant management. Materials and Methods: We retrospectively analyzed 386 LDLT cases, and patients were divided into low-MELD (<20, n=293) vs. highMELD (≥20, n=93) groups according to their MELD score at the time of index hospitalization. Patients in the high-MELD group were managed specifically according to a treatment algorithm in an effort to decrease the MELD score. Patients in the high-MELD group were further divided into 2 subgroups: (1) responders (n=34) to pre-transplant treatment with subsequent reduction of the MELD score by a minimum of 1 point vs. (2) non-responders (n=59), whose MELD score remained unchanged or further increased on the day of LDLT. Responders vs. non-responders were compared according to etiology, demographics, and survival.

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Cite This Article

ACAR, Ş., AKYILDIZ, M., GÜRAKAR, A., TOKAT, Y., DAYANGAÇ, M. (2020). Delta MELD as a predictor of early outcome in adult-to-adult living donor liver transplantation. Turkish Journal of Gastroenterology, Cilt: 31 - Sayı: 11, 782–789. https://ajindex.com/articles/408718

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