Journals / Çocuk Enfeksiyon Dergisi / 2021 / Cilt: 15 - Sayı: 1

Parechovirus Infection Mimicking Bacterial Sepsis in an Infant

Bir İnfantta Bakteriyel Sepsisi Taklit Eden Parekovirüs Enfeksiyonu

Pages
44–47
DOI
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⚡ TL;DR(Too Long; Didn't Read)

This is a report of a 38-day-old febrile infant admitted with a sepsis-like clinical condition and diagnosed with HPeV meningitis through cerebrospinal fluid PCR test

📌 3 Key Takeaways

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Objective & Hypothesis:Human parechoviruses (HPeV) are responsible for gastrointestinal and respiratory system infections which are seen mostly in the first year of life.
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Key Findings & Data:It is known that HPeV may cause sepsis like syndrome and meningoencephalitis in neonates and infants.
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Conclusion & Impact:This is a report of a 38-day-old febrile infant admitted with a sepsis-like clinical condition and diagnosed with HPeV meningitis through cerebrospinal fluid PCR test
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Human parechoviruses (HPeV) are responsible for gastrointestinal and respiratory system infections which are seen mostly in the first year of life. It is known that HPeV may cause sepsis like syndrome and meningoencephalitis in neonates and infants. Although the prognosis of central nervous system infections caused by HPeV are suggested to be quite good and similar to enteroviruses, there are reports of severe cases which cause encephalitis and neurological sequels. The use of polymerase chain reaction (PCR) test in diagnosis may reduce antibiotic use and length of hospital stay. There are no specific antiviral agents for treatment. This is a report of a 38-day-old febrile infant admitted with a sepsis-like clinical condition and diagnosed with HPeV meningitis through cerebrospinal fluid PCR test

Özet

İnsan parekovirüsleri (HPeV), sıklıkla doğumdan sonraki ilk yıl içinde görülen gastrointestinal ve respiratuvar sistem enfeksiyonlarından sorumludur. Yenidoğanlarda ve süt çocuklarında sepsis benzeri sendrom ve meningoensefalite neden oldukları bilinmektedir. Genelde HPeV’in sebep olduğu santral sinir sistemi (SSS) enfeksiyonlarının klinik gidişinin enterovirüslerin seyrine benzediği ve iyi seyirli olduğu düşünülse de, ensefalit ve nörolojik sekellere sebep olan ağır tablolar da bildirilmiştir. Polimeraz zincir reaksiyonu (PZR) testinin kullanılarak etkenin gösterilmesi, hastanede yatış süresini kısaltabilir ve antibiyotik kullanımını azaltabilir. Tedavide önerilen özgül bir antiviral ajan yoktur. Burada, sepsis benzeri bir klinik ile başvuran ve beyin omurilik sıvısı (BOS) PZR tetkiki ile parekovirüs menenjiti tanısı alan 38 günlük, yüksek ateşli bir süt çocuğu sunulmuştur.

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Cite This Article

TOKMAK, D. N., YALÇINKAYA, R., GÜLENÇ, N., ÖZ, F. N., KAMAN, A., TEKE, T. A., DURMUŞ, S. Y., TANIR, G. (2021). Parechovirus Infection Mimicking Bacterial Sepsis in an Infant. Çocuk Enfeksiyon Dergisi, Cilt: 15 - Sayı: 1, 44–47. https://ajindex.com/articles/406932

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References (1)

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