Journals / Turkish Neurosurgery / 2013 / Cilt: 23 - Sayı: 5

Hipofiz Abselerinin Tanı ve Tedavisi: Olgu Serisi ve Literatür Değerlendirilmesi

Diagnosis and Management of Pituitary Abscess A Case Series and Review of the literature

Pages
611–616
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Additionally, these cases should be closely followed-up in terms of pituitary insufficiency, surgical complications and infection.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: Pituitary abscess is a disorder characterized with central nervous system (CNS) infection, mass effect, and endocrine dysfunction.
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Key Findings & Data:MATERIAL and METHODS: Following detailed clinical and hormonal examinations and imaging tests, 210 cases of pituitary adenoma and other sellar pathologies were operated on at the Neurosurgery clinic of Göztepe Training and Research Hospital.
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Conclusion & Impact:Additionally, these cases should be closely followed-up in terms of pituitary insufficiency, surgical complications and infection.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIM: Pituitary abscess is a disorder characterized with central nervous system (CNS) infection, mass effect, and endocrine dysfunction. These abscesses generally occur due to hematogenous spread in conditions such as paranasal sinusitis, sepsis, and where the blood brain barrier breaks down. This paper aims to discuss four cases of preoperatively diagnosed pituitary abscess in the light of the literature. MATERIAL and METHODS: Following detailed clinical and hormonal examinations and imaging tests, 210 cases of pituitary adenoma and other sellar pathologies were operated on at the Neurosurgery clinic of Göztepe Training and Research Hospital. Results: All the patients showed fever, systemic signs of toxemia and endocrine dysfunction at the time of diagnosis. In these cases, a preoperative diagnosis of the disease was made thanks to characteristic MRI findings. The four cases were operated by the transnasal transsphenoidal approach and histopathological and microbiological studies were performed for surgical specimens. CONCLUSION: Pituitary abscesses are rare disorders responsible for a high mortality risk. Mortality and morbidity can be reduced by early surgical drainage and appropriate antibiotic treatments. Additionally, these cases should be closely followed-up in terms of pituitary insufficiency, surgical complications and infection.

Özet

AMAÇ: Hipofiz absesi merkezi sinir sistemi (MSS) infeksiyonu, kitle etkisi ve endokrin bozuklukları ile karakterize bir hastalıktır. Bu apseler genellikle kan beyin bariyerinin yıkıldığı hematojen yolla yayılan paranasal sinüzit, sepsis gibi durumulara bağlı oluşur. Bu yazıda literatür ışığında preoperatif tanısı pitüiter apse olan dört olgu tartışılmaktadır. YÖNTEM ve GEREÇLER: Ayrıntılı klinik, hormonal incelemeleri ve görüntüleme testleri takiben hipofiz adenomu ve diğer sellar patolojileri olan 210 olgu Göztepe Eğitim ve Araştırma Hastanesi Beyin Cerrahisi kliniğinde ameliyat edildi. BULGUlAR: Tüm hastalar tanı sırasında ateş, toksemi ve endokrin bozukluklarının sistemik belirtilerini gösterdi. Bu olgularda, hastalığın preoperatif tanısı karakteristik MRG bulguları sayesinde yapıldı. Bu dört olgu transnazal transsfenoidal yaklaşımla opere edildi ve histopatolojik, mikrobiyolojik çalışmalar cerrahi numunelere yapıldı. SONUÇ: Hipofiz apseleri yüksek mortalite riskinden sorumlu nadir bir hastalık grubudur. Mortalite ve morbidite erken cerrahi drenaj ve uygun antibiyotik tedavisi ile azaltılabilir. Ayrıca, bu durumlarda hipofizer yetmezlik, cerrahi komplikasyonlar ve enfeksiyon yönünden yakından takip edilmelidir.

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Cite This Article

ALTAŞ, M., SEREFHAN, A., SİLAV, G., ÇERÇİ, A., COSKUN, K. K., ELMACI, İ. (2013). Hipofiz Abselerinin Tanı ve Tedavisi: Olgu Serisi ve Literatür Değerlendirilmesi. Turkish Neurosurgery, Cilt: 23 - Sayı: 5, 611–616. https://ajindex.com/articles/405502

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References (1)

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