Journals / Turkish Neurosurgery / 2014 / Cilt: 24 - Sayı: 4

Atrofik Dilatasyonu Normal Basınçlı Hidrosefaliden Ayırt Etmek ve Faz Kontrast MRG ile Cerrahi Faydayı Öngörme

Normal Pressure Hydrocephalus versus Atrophic Dilatation to Distinguish and Predict the Benefits of Surgical Intervention with a Phase-Contrast MRI Technique

Pages
525–531
DOI
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CONCLUSION: The mean CSF flow rate may be useful in the diagnosis and differential diagnosis, and the prediction of the potential benefits of surgical intervention for patients considered to have INPH.

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Objective & Hypothesis:AIM: To compare mean cerebrospinal fluid (CSF) volume in the aqueduct by using phase-contrast magnetic resonance imaging for the patients with idiopathic normal pressure hydrocephalus (INPH) and atrophic dilation (AD) to investigate the efficacy of this technique in predicting surgery.
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Key Findings & Data:MATERIAL and METHODS: The MR images of a total of 80 individuals, consisting of 30 patients considered to have INPH, 20 patients with AD not proportional with cerebral sulci, and 30 control cases without a hydrocephalus clinical picture, were evaluated retrospectively.
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Conclusion & Impact:CONCLUSION: The mean CSF flow rate may be useful in the diagnosis and differential diagnosis, and the prediction of the potential benefits of surgical intervention for patients considered to have INPH.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIM: To compare mean cerebrospinal fluid (CSF) volume in the aqueduct by using phase-contrast magnetic resonance imaging for the patients with idiopathic normal pressure hydrocephalus (INPH) and atrophic dilation (AD) to investigate the efficacy of this technique in predicting surgery. MATERIAL and METHODS: The MR images of a total of 80 individuals, consisting of 30 patients considered to have INPH, 20 patients with AD not proportional with cerebral sulci, and 30 control cases without a hydrocephalus clinical picture, were evaluated retrospectively. The minute mean aqueductal CSF flow rates of the three groups were compared using the Kruskall-Wallis analysis of variance, and the inter-group statistical comparisons were made using the Mann-Whitney U test. RESULTS: The mean aqueductal flow rates were 46.56 ± 25.06 ml/min for the INPH group, 9.28 ± 4.68 ml/min for the AD group, and 8.68 ± 3.40 ml/min for the control group. The mean flow rate of the INPH group was significantly higher than those of the control and ADH groups (p < 0.001). CONCLUSION: The mean CSF flow rate may be useful in the diagnosis and differential diagnosis, and the prediction of the potential benefits of surgical intervention for patients considered to have INPH.

Özet

AMAÇ: Faz kontrast manyetik rezonans görüntüleme kullanarak, idiyopatik normal basınçlı hidrosefali (İNBH) li hastalar ile atrofik dilatasyonu (AD) bulunan hastalarda akuaduktustaki ortalama beyin omurilik sıvısı (BOS) volümünü karşılaştırmak ve bu tekniğin cerrahi yararı öngörmedeki etkinliğini araştırmaktır. YÖNTEM ve GEREÇLER: İNBH olarak değerlendirilen 30 hasta, serebral sulkuslar ile orantısız AD bulunan 20 hasta, hidrosefali kliniği bulunmayan kontrol grubu 30 olgu olmak üzere toplam 80 olgunun MR görüntüleri retrospektif olarak incelendi. Üç grup arasında akuaduktustaki dakikalık ortalama BOS debileri Kruskall-Wallis varyans analizi ile, gruplar birbirleri ile Mann-Whitney U testi ile istatistiksel olarak karşılaştırıldı. BULGULAR: Akuaduktus düzeyinden elde edilen ortalama debi değerleri; İNBH grubunda 46,56 ± 25,06 ml/dk, AD grubunda 9,28 ± 4,68 ml/ dk, kontrol grubunda 8,68 ± 3,40 ml/dk idi. İNBH grubundaki ortalama debi, kontrol grubu ve AD grubu ile karşılaştırıldığında istatistiksel olarak anlamlı fazla bulundu (p < 0,001). SONUÇ: Ortalama BOS debi oranları, İNBH düşünülen olgularda tanıda, ayırıcı tanıda ve cerrahi yararı öngörmede faydalı olabilir.

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Cite This Article

ASLAN, K., TOKATLIOĞLU, O., AYDIN, R., POLAT, A. V., İNCESU, L. (2014). Atrofik Dilatasyonu Normal Basınçlı Hidrosefaliden Ayırt Etmek ve Faz Kontrast MRG ile Cerrahi Faydayı Öngörme. Turkish Neurosurgery, Cilt: 24 - Sayı: 4, 525–531. https://ajindex.com/articles/405488

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