Journals / Turkish Neurosurgery / 2015 / Cilt: 25 - Sayı: 6

Posterior Komissür’ün Anatomisi

The Anatomy of the Posterior Commissure

Pages
837–843
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, further human cadaveric studies are necessary

📌 3 Key Takeaways

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Objective & Hypothesis:AIm: The connections of posterior commissure are defined.
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Key Findings & Data:The specimens were fixed in 10% formalin solution for 3 weeks.
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Conclusion & Impact:However, further human cadaveric studies are necessary
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIm: The connections of posterior commissure are defined. Its fibers mediate the consensual light reflex by interconnecting the pretectal nuclei. The fiber connections from the thalamic, pretectal, superior colliculus and the habenular nuclei are known, but they have not been shown anatomically. The present study is a fiber dissection study to define the anatomy of the posterior commissure.mAterIAl and methOds: Twenty formalin-fixed sheep heads were used in the study. The specimens were fixed in 10% formalin solution for 3 weeks. The arachnoidal and vascular structures were removed by using a surgical microscope magnification (x6-x40) and brains were again fixed for 4 weeks at -20°C. The fiber dissections were performed at Marmara University, Rhoton Laboratory. Also, a radiological tractographic study was carried on five healthy volunteers to see the posterior commissure cortical connections. results: In fifteen sheep brains, the dimensions of the posterior commissure were measured as 1.36 mm (range 0.5-2.5 mm) width, and as 4.6 mm (range 3-6 mm) length. In the dissection study, a frontotemporooccipital fascicle was observed to connect with the fibers of the posterior commissure. Diffusion tensor imaging scans showed the frontotemporooccipital tract to extend to posterior commissural region. COnClusIOn: To our knowledge, this is the first anatomical and tractographic study regarding the posterior commissure. However, further human cadaveric studies are necessary

Özet

AmAÇ: Posterior komissür'ün lifleri, pretektal nükleusları bağlayarak konsensual ışık refleksine aracı olur. Talamik, pretektal, tektal, superior kolikulus lifleri ve habenular çekirdeklerin liflerinin posterior komissür'de çaprazlaştığı bilinmektedir. Ancak anatomik olarak gösterilmemiştir. Posterior komissür anatomisini tanımlamak için yapılan lif diseksiyon çalışması sunulmuştur. yÖntem ve GereÇler: Yirmi koyun beyninde Marmara Üniversitesi Rhoton Laboratuvarı'nda diseksiyon yapıldı. Spesimenler %10 formalin solüsyonunda 3 hafta bekletildi. Cerrahi mikroskop (x6-x40) altında araknoid-vasküler yapılar çıkartılarak beyinler -20°C'de bekletildi. Beş beyin, posterior fiksasyon-diseksiyon yetersiz olduğu için çalışmadan çıkartıldı. Beş beyinde anterior, lateral, posterior ve medial diseksiyon yapılarak her aşamada fotoğraflandı. On beyinde posterior komissür ortaya konacak şekilde hipokampal komissür düzeyinden diseksiyon yapıldı. Radyolojik çalışmada 5 gönüllü hastaya, difüzyon tensor görüntüleme yapılarak posterior komissür'ün lif bağlantısı incelendi. BulGulAr: On beş koyun beyninde posterior komissür'ün ortalama kalınlığı 1,36 mm (0,5-2,5 mm), uzunluğu 4,6 mm (3-6 mm) olarak bulundu. Posterior komissür'ün her iki tarafta superior ve inferior kolikulusları bağladığı; habenula, pretektal, tektal ve periakuaduktal bölgeden kısa liflerle bağlantı kurduğu görüldü. Bazı spesimenlerde hipokampal komissür liflerinin splenial bölgede bu liflere eşlik ettiği izlendi. Talamik diseksiyondan sonra gözlenen frontotemporooksipital fasikülün posterior komissür'e uzandığı saptandı. sOnuÇ: Çalışmada diseksiyonla posterior komissür'ün frontotemporooksipitopontin bağlantısı gösterilmiştir. Araştırma posterior komissür'ün lif bağlantılarını ortaya koyacak insan kadavra çalışmalarıyla desteklenmelidir

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Cite This Article

OZDEMIR, N. G. (2015). Posterior Komissür’ün Anatomisi. Turkish Neurosurgery, Cilt: 25 - Sayı: 6, 837–843. https://ajindex.com/articles/405423

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References (1)

  1. Davies KG, Daniluk S: Importance of individual variation of anterior commissure-posterior commissure-derived subthalamic nucleus coordinates in deep brain stimulation targeting. Stereotact Funct Neurosurg 86(4):266-267, 2008 2. Fernández-Miranda JC, Rhoton AL Jr, Alvarez-Linera J, Kakizawa Y, Choi C, de Oliveira EP: Three-dimensional microsurgical and tractographic anatomy of the white matter of the human brain. Neurosurgery 62(6 Suppl 3):989-1026, 2008 3. Grondona JM, Hoyo-Becerra C, Visser R, Fernández-Llebrez P, López-Ávalos MD: The subcommissural organ and the development of the posterior commissure. Int Rev Cell Mol Biol 296: 63-137, 2012 4. Hoyo-Becerra C, López-Avalos MD, Cifuentes M, Visser R, Fernández-Llebrez P, Grondona JM: The subcommissural organ and the development of the posterior commissure in chick embryos. Cell Tissue Res 339(2):383-395, 2010 5. Keene MF: The connexions of the posterior commissure: A study of its development and myelination in the human foetus and young infant, of its phylogenetic development, and of degenerative changes resulting from certain experimental lesions. J Anat 72(Pt 4):488-501, 1938 6. Lara MH: Periaqueductal neurons associated to the posterior commissure: A morphological study in the hedgehog, rat and cat. Anat Anz 159(1-5):195-201, 1985 7. Maheshwari M, Klein A, Ulmer JL: White matter: Functional anatomy of key tracts. In: Faro SH, Feroze BM, Law M (eds). Functional Neuroradiology: Principles and Clinical Applications. NewYork: Springer, 2012:767-783 8. Mandonnet E, Nouet A, Gatignol P, Capelle L, Duffau H: Does the left inferior longitudinal fasciculus play a role in language? A brain stimulation study. Brain 130(Pt 3):623-629, 2007 9. Mulroy E, Murphy S, Lynch T: Alexia without agraphia. Ir Med J 104(4):124, 2011 10. Peltier J, Verclytte S, Delmaire C, Pruvo JP, Havet E, Gars DL: Microsurgical anatomy of the anterior commissure: Correlations with diffusion tensor imaging fiber tracking and clinical relevance. Operative Neurosurgery 69: 241-247, 2011 11. Peuskens D, van Loon J, Van Calenbergh F, van den Bergh R, Goffin J, Plets C: Anatomy of the anterior temporal lobe and the frontotemporal region demonstrated by fiber dissection. Neurosurgery 55(5):1174-1184, 2004 12. Raybaud C: The corpus callosum, the other great forebrain commissures, and the septum pellucidum: Anatomy, development, and malformation. Neuroradiology 52(6):447- 477, 2010 13. Sargon MF, Mas N, Senan S, Ozdemir B, Celik HH, Cumhur M: Qua