Journals / Turkish Neurosurgery / 2009 / Cilt: 19 - Sayı: 4

Yetişkinlerde spontan primer intraventriküler kanama: Klinik bulgular, etiyoloji ve sonuçları

Spontaneous primary tntraventricular hemorrhage in adults: Clinical data, etiology and Outcome

Pages
338–344
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The neurological status of the patients and an early developing hydrocephalus are the most important risk factors.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: Primary intraventricular hemorrhage (PIVH), bleeding in the ventricular system without a recognizable parenchymal component, is a rare neurological disorder.
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Key Findings & Data:MATERIAL and METHODS: We retrospectively reviewed the clinical data, complementary examinations, outcome and computed tomography (CT) IVH score of 24 patients in our hospital from 2004 to 2008.
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Conclusion & Impact:The neurological status of the patients and an early developing hydrocephalus are the most important risk factors.
🔬Design:Review & Systematic Survey
📍Scope:2004 Verileri
⚙️Variables:Domain Parameters

Abstract

AIM: Primary intraventricular hemorrhage (PIVH), bleeding in the ventricular system without a recognizable parenchymal component, is a rare neurological disorder. The purpose of this study was to identify clinical features, risk factors, etiology and outcome of patients with PIVH. MATERIAL and METHODS: We retrospectively reviewed the clinical data, complementary examinations, outcome and computed tomography (CT) IVH score of 24 patients in our hospital from 2004 to 2008. We identified 24 patients with the inclusion criteria of non-traumatic PIVH. Their mean age was 60.6±17.4 years (range 38-79). Fourteen patients were male and 10 were female. RESULTS: The major symptoms included headache (n=24), loss of consciousness (n=6), confusion and disorientation (n=14), nausea/vomiting (n=10). Angiography revealed vascular malformations in five patients (21%). Other possible causative factors were hypertension in 12 patients (50%) and clotting disorder in one. The aetiology remained unknown in six patients. Most PIVH patients had associated hydrocephalus (58%) and 37% of the patients required ventricular drainage. In-hospital mortality was high (41%) and a FOUR score ≤10, GCS ≤8 and early hydrocephalus were independent predictors of mortality. CONCLUSION: Hypertension is the most common associated risk factor for PIVH followed by vascular malformation. Spontaneous resorption and rebleeding may be seen. The neurological status of the patients and an early developing hydrocephalus are the most important risk factors.

Özet

AMAÇ: Primer intraventriküler kanamalar (PİVK), intraparankimal kanama olmaksızın ventriküler sistem içinde kan olması şeklinde tanımlanmıştır. Spontan ve non-travmatik olarak da adlandırılan PIVK’lar oldukça nadir gözlenir. Özellikle PİVK’ların klinik özellikleri ve prognozlarına ait veri oldukça azdır. Bu çalışmanın amacı, PİVK’lı 24 erişkin hastanın klinik özelliklerini, risk faktörlerini, etiyolojisini ve prognozunu araştırmaktır. YÖNTEM ve GEREÇ: Hastanemizde 2004-2008 yılları arasında takip edilen 24 PİVK’lı hasta retrospektif olarak klinik bulgular, geniş nörolojik değerlendirme, prognoz ve bilgisayarlı beyin tomografi-intraventriküler kanama skorları açısından değerlendirilmiştir. Travmatik olmayan PİVK’lı hasta sayısı 24 idi. Hastaların yaş ortalaması 60,6±17,4 yıl idi. BULGULAR: Ana bulgular başağrısı (n=24), bilinç kaybı (n=6), konfüzyon veya dezorientasyon (n=14), bulantı/kusma (n=10) idi. Beş hastada (%21) anjiyografide malformasyon tespit edildi. Diğer muhtemel nedenler; 12 hastada hipertansiyon (%50) ve bir hastada pıhtılaşma bozukluğu saptandı. Altı hastada ise etiyoloji tespit edilemedi. PİVK’lı hastaların %58’sinde hidrosefali gelişti ve %37’sinde eksternal ventriküler drenaj takılmasına ihtiyaç duyuldu. Hastane mortalitesi yüksek bulundu (%41). Full Outline of Unresponsiveness Score ≤10, Glasgow Koma Skorunun ≤8 olması ve erken hidrosefali mortaliteyi etkileyen faktörlerdi. SONUÇ: Vasküler malformasyonlar hipertansiyondan sonra PİVK’lara en sık eşlik eden risk faktörüdür. Spontan rezorbsiyon ve tekrarlayan kanama görülebilir. Hastaların nörolojik durumları ile gelişebilecek erken hidrosefali prognozu belirleyen en önemli faktörlerdir. PİVK olgularında mortalite oranını düşürecek yeni tedavi stratejilerine ihtiyaç duyulmaktadır.

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Cite This Article

GİRAY, S., ŞEN, O., SARICA, F. B., TUFAN, K., KARATAŞ, M., GÖKSEL, K. B., YERDELEN, V. D., ÇEKİNMEZ, M., CAN, U. (2009). Yetişkinlerde spontan primer intraventriküler kanama: Klinik bulgular, etiyoloji ve sonuçları. Turkish Neurosurgery, Cilt: 19 - Sayı: 4, 338–344. https://ajindex.com/articles/405220

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