Journals / Turkish Neurosurgery / 2011 / Cilt: 21 - Sayı: 4

Bilgisayarlı tomografi rehberliğinde stereotaktik beyin biyopsisi tekniğinin güvenilirliği ve tanısal değeri

The safety and diagnostic value of frame-based and ct-guided stereotactic brain biopsy technique

Pages
582–590
DOI
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⚡ TL;DR(Too Long; Didn't Read)

ConclusIon: Our findings support that frame based-stereotactic biopsy is a safe and valuable technique that allows the neurosurgeon to obtain tissue samples for histopathological diagnosis of intracranial mass lesions in almost any region.

📌 3 Key Takeaways

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Objective & Hypothesis:AIm: Histopathological diagnosis is always necessary to make an effective treatment plan for intracranial mass lesions.
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Key Findings & Data:Ma terIal and Methods: A total of 290 cases undergoing CT-guided stereotactic biopsy for intracranial lesions were included in this retrospective study.
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Conclusion & Impact:ConclusIon: Our findings support that frame based-stereotactic biopsy is a safe and valuable technique that allows the neurosurgeon to obtain tissue samples for histopathological diagnosis of intracranial mass lesions in almost any region.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIm: Histopathological diagnosis is always necessary to make an effective treatment plan for intracranial mass lesions. This study aimed to evaluate the diagnostic efficacy, and associated mortality and morbidity of CT-guided stereotactic biopsy procedures in a large number of patients with intracranial lesions. Ma terIal and Methods: A total of 290 cases undergoing CT-guided stereotactic biopsy for intracranial lesions were included in this retrospective study. Clinical, radiological and histological data in patient records were examined. Results: The mean age of the patients was 46.6 years (range: 2-82 y). Pediatric patients comprised 6.3% (n=13) of the total population. Examination of paraffin embedded histological preparations revealed a tumoral mass in 240 (82.8%), a non-tumoral mass in 37 (12.8%), and non-definable lesions in 13 (4.5%). Therefore, the diagnostic value in this series was 95.5%. Postoperative mortality rate was 0.8% (n=2). When histopathological diagnoses made after biopsy and surgical resection were compared in 42 patients with available data, a complete or partial agreement was present in 90.5%. ConclusIon: Our findings support that frame based-stereotactic biopsy is a safe and valuable technique that allows the neurosurgeon to obtain tissue samples for histopathological diagnosis of intracranial mass lesions in almost any region.

Özet

AMAÇ: İntrakraniyal kitle lezyonlarında etkili bir tedavi planı yapabilmek için histopatolojik tanı her zaman gereklidir. Bu çalışmada, intrakraniyal lezyonu olan büyük bir hasta grubunda BT rehberliğinde yapılan stereotaktik biyopsi işleminin tanısal değeri ve bu işlemle ilişkili morbidite ve mortalite değerlendirilmiştir. YÖNTEM ve GEREÇLER: İntrakraniyal lezyon nedeniyle BT rehberliğinde stereotaktik biyopsi yapılan toplam 290 olgu bu retrospektif çalışmaya alınmıştır. Hasta kayıtlarındaki klinik, radyolojik ve histolojik veriler incelenmiştir. BULGULAR: Hastaların ortalama yaşı 46.6’dır (aralık: 2-82). Toplam hasta popülasyonunun %6.3’ü (n=13) çocuk hastalardır. Histopatolojik inceleme sonucunda hastaların 240’ında (%82.8) tümoral kitle, 37’sinde (%12.8) tümöral olmayan kitle, 13’ünde ise (%4.5) tanımlanamayan lezyon bulunmuştur. Dolayısıyla, bu seride tanısal değer %95.5’dir. Postoperatif mortalite oranı %0.8 (n=2) olarak gerçekleşmiştir. Biyopsi sonucu ve cerrahi rezeksiyon sonucu histopatolojik tanılar verisi bulunan 42 hastada karşılaştırıldığında, %90.5 oranında kısmi ya da tam uyum saptanmıştır. SONUÇ: Bulgularımız bilgisayarlı tomografi rehberliğinde frame tabanlı stereotaktik biyopsinin güvenli ve değerli bir teknik olduğunu desteklemektedir. Bu teknik, cerrahın intrakraniyal kitle lezyonlarından histopatolojik tanı için doku örnekleri almasına olanak tanımaktadır.

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Cite This Article

ERŞAHİN, M., KARAASLAN, N., GÜRBÜZ, M. S., HAKAN, T., BERKMAN, M. Z., EKİNCİ, O., DENİZLİ, N., VARDAR, F. A. (2011). Bilgisayarlı tomografi rehberliğinde stereotaktik beyin biyopsisi tekniğinin güvenilirliği ve tanısal değeri. Turkish Neurosurgery, Cilt: 21 - Sayı: 4, 582–590. https://ajindex.com/articles/405085

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