Journals / Turkish Neurosurgery / 2012 / Cilt: 22 - Sayı: 4

Bilateral subtalamik derin beyin stimülasyonunun Parkins

Long-term benefit of bilateral subthalamic deep brain stimulation on camptocormia in Parkinson’s disease

Pages
489–492
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The optimal target has yet to be defined and further work on appropriate patient selection is needed.

📌 3 Key Takeaways

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Objective & Hypothesis:We report the case of a 63-year-old female with a long history of severe Parkinson’s disease (PD) and subsequent onset of debilitating camptocormia who underwent successful bilateral subthalamic nucleus deep brain stimulation surgery (STN DBS).
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Key Findings & Data:Five year postoperatively, the patient has enjoyed good results for both her PD symptoms as well as significant and sustained improvement in her thoracolumbar flexion deformity.
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Conclusion & Impact:The optimal target has yet to be defined and further work on appropriate patient selection is needed.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

We report the case of a 63-year-old female with a long history of severe Parkinson’s disease (PD) and subsequent onset of debilitating camptocormia who underwent successful bilateral subthalamic nucleus deep brain stimulation surgery (STN DBS). The literature and previous reports are reviewed. The patient history and details of the surgical procedure are reported including the implantable pulse generator (IPG) settings and response to stimulation. The results of her PD symptom and camptocormia improvements are discussed. Five year postoperatively, the patient has enjoyed good results for both her PD symptoms as well as significant and sustained improvement in her thoracolumbar flexion deformity. She remains on minimal medications and no longer requires any assistive devices for ambulation. Comparison and contrast of the current world literature on DBS for camptocormia is reviewed. We discuss the current targets used for DBS in the setting of camptocormia in the cases reported, both PD associated and not associated. The optimal target has yet to be defined and further work on appropriate patient selection is needed.

Özet

Uzun süredir şiddetli Parkinson hastalığı (PH) ve yakın zamanda maluliyete neden olan kamptokormisi olan ve bilateral subtalamik nükleus derin beyin stimülasyon cerrahisinin (STN DBS) başarıyla yapıldığı 63 yaşında bir kadın hastayı sunuyoruz. Literatür ve önceki raporlar gözden geçirilmektedir. Hasta öyküsü ve implante edilen puls jeneratörü (IPG) ayarları ve stimülasyona cevap dahil olmak üzere cerrahi işlem ayrıntıları bildirilmiştir. PD belirtilerinin sonuçları ve kamptokormideki gelişmeler anlatılmaktadır. Ameliyattan beş yıl sonra hasta halen PD belirtileri açısından iyi sonuçlar ve torakolumbar fleksiyon deformitesinde önemli ve uzun süreli iyileşme mevcuttu. Hasta çok az sayıda ilaç kullanmakta ve artık ambulasyon için yardımcı cihazlara gereksinim duymamaktadır. Kamptokormi için DBS konusunda mevcut dünya literatürü bilgileri karşılaştırılmış ve değerlendirilmektedir. Bildirilen vakalarda PD ile ilişkili olsun veya olmasın kamptokormi durumunda DBS için kullanılan mevcut hedefleri gözden geçiriyoruz. Optimum hedefin halen tanımlanması gerekmektedir ve uygun hasta seçimi açısından hâlâ yapılması gerekenler vardır.

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Cite This Article

LYONS, M., BOUCHER, O., PATEL, N., BIRCH, B., EVIDENTE, V. (2012). Bilateral subtalamik derin beyin stimülasyonunun Parkins. Turkish Neurosurgery, Cilt: 22 - Sayı: 4, 489–492. https://ajindex.com/articles/405019

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References (1)

  1. Ballenger JC: A case of camptocormia occurring in psychotherapy. J Nerv Ment Dis 162:291-294, 1976 2. Divry P: Camptocormia post-traumique. Liege Med 22: 585-590, 1929 3. Djaldetti R, Mosberg-Galili R, Sroka H, Merims D, Melamed E: Camptocormia (bent spine) in patients with Parkinson’s Disease-Characterization and possible pathogenesis of an unusual phenomenon. Mov Disorders 14:443-447, 1999 4. Fetterman JL: Back disorders of psychic origin. Ohio State Med J 33:777-781, 1937 5. Hurst AF: The bent back of soldiers. Br Med J 2:621-624, 1918 6. Karbowski K: The old and new camptocormia. Spine 24: 1494-1498, 1999 7. Kleiner-Fisman G, Liang GS, Moberg PJ, Ruocco AC, Hurtig HI, Baltuch GH, Jaggi JL, Stern MB: Subthalamic nucleus deep brain stimulation for severe idiopathic dystonia: Impact on severity, neuropsychological status, and quality of life. J Neurosurg 107(1):29-36, 2007 8. Krack P, Batir A, van Blercom N, Chabardes S, Fraix V, Ardoiun C, Koudsie A, Limousin PD, Benazzouz A, LeBas JF, Benabid AL, Pollak P: Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson’s disease. N Engl J Med 349:1925-1934, 2003 9. Krauss JK: Brain stimulation for dystonia in adults. Overview and developments. Stereotact Funct Neurosurg 78:168-182, 2002 10. Massa E, Slater CB: Camptocormia and depression: A case report. Mil Med 154:352-355, 1989 11. Micheli F, Cersosimo MG, Piedimonte F: Camptocormia in a patient with Parkinson’s disease: beneficial effects of pallidal deep brain stimulation. Case report. J Neurosurg 103: 1081-1083, 2005 12. Moro E, Scerrati M, Romito LM, Roselli R, Tonali P, Albanese A: Chronic subthalamic nucleus stimulation reduces medication requirements in Parkinson’s disease. Neurology 53:85-90, 1999 13. Nandi D, Parkin S, Scott R, Winter JL, Joint C, Gregory R, Stein J, Aziz TZ: Camptocormia treated with bilateral pallidal stimulation. Case report. Neurosurg Focus 12:1-6, 2002 14. Nieves AV, Miyasaki JM, Lang AE: Acute onset dystonic camptocormia caused by lenticular lesions. Mov Disord 16:177-180, 2001 15. Okun MS, Fernandez HH, Wu SS, Kirsch-Darrow L, Bowers D, Bova F, Suelter M, Jacobson CE 4th, Wang X, Gordon CW Jr, Zeilman P, Romrell J, Martin P, Ward H, Rodriguez RL, Foote KD: Cognition and mood in Parkinson’s disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: The COMPARE trial. Ann Neurol 65:586-595, 2009 16. Pastor-Gomez J, Hemando-Requejo V, Luvengo-Dos Santos A, Pedrosa