Journals / Turkish Neurosurgery / 2015 / Cilt: 25 - Sayı: 4

İnme için Doku Plazminojen Aktivatörünün İntravenöz Uygulanmasından Sonra Acil Orta Serebral Arter - Süperfisiyal Temporal Arter Bypass

Emergency Superficial Temporal Artery to Middle Cerebral Artery Bypass After Intravenous Administration of Tissue Plasminogen Activator for Stroke

Pages
633–637
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, it is recommended that invasive procedures should be avoided soon after IVtPA administration because tPA is believed to exert prolonged fibrinolytic effects may continue for more than 24 hours.

📌 3 Key Takeaways

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Objective & Hypothesis:Intravenous tissue plasminogen activator (IVtPA) is effective for the treatment of acute stroke.
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Key Findings & Data:However, it is recommended that invasive procedures should be avoided soon after IVtPA administration because tPA is believed to exert prolonged fibrinolytic effects may continue for more than 24 hours.
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Conclusion & Impact:We believe that superficial temporal artery to middle cerebral artery bypass can be safely performed even within 24 hours after IVtPA administration.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Intravenous tissue plasminogen activator (IVtPA) is effective for the treatment of acute stroke. Although IVtPA is easily administered and is effective in many cases, the clinical condition of some patients can worsen after the initiation of thrombolytic therapy due to sustained cerebrovascular insufficiency. In such cases, several additional treatment options to re-establish cerebral perfusion are available, including superficial temporal artery to middle cerebral artery bypass. However, it is recommended that invasive procedures should be avoided soon after IVtPA administration because tPA is believed to exert prolonged fibrinolytic effects may continue for more than 24 hours. We described three cases of emergency superficial temporal artery to middle cerebral artery bypass performed within 24 hours of IVtPA administration, and discussed the safety of such procedures. We believe that superficial temporal artery to middle cerebral artery bypass can be safely performed even within 24 hours after IVtPA administration.

Özet

İntravenöz doku plazminojen aktivatörü (IVtPA) akut inme tedavisinde etkilidir. IVtPA birçok olguda kolayca uygulanmasına ve etkili olmasına rağmen bazı hastaların klinik durumu uzun süreli serebrovasküler yetmezlik nedeniyle trombolitik tedavi başlatıldıktan sonra kötüye gidebilir. Bu gibi durumlarda, serebral perfüzyonu tekrar oluşturmak için yüzeysel temporal arter - orta serebral arter bypass dahil olmak üzere birkaç tedavi seçeneği vardır. Ancak IVtPA uygulanması sonrasında hemen invaziv işlemler yapılmasından kaçınılması önerilmektedir çünkü tPA'nın 24 saate kadar sürebilen uzun süreli fibrinolitik etkileri olduğuna inanılmaktadır. IVtPA uygulanmasından sonraki 24 saatte yapılan üç acil süperfisiyal temporal arter - orta serebral arter bypass işlemini tanımlıyor ve bu tür işlemlerin güvenliğini tartışıyoruz. Süperfisiyal temporal arter - orta serebral arter bypass işleminin IVtPA uygulamasından sonraki 24 saat içinde bile güvenle yapılabileceğine inanıyoruz.

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Cite This Article

TAKEUCHI, S., WADA, K., ARIMOTO, H., KUMAGAI, K., OSADA, H., MORI, K. (2015). İnme için Doku Plazminojen Aktivatörünün İntravenöz Uygulanmasından Sonra Acil Orta Serebral Arter - Süperfisiyal Temporal Arter Bypass. Turkish Neurosurgery, Cilt: 25 - Sayı: 4, 633–637. https://ajindex.com/articles/404740

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References (3)

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