To our knowledge, no MRS and DSC findings have been reported in the literature yet
📌 3 Key Takeaways
🎯
Objective & Hypothesis:We report imaging findings of a 64-year-old male patient with a ruptured epidermoid cyst (EC) known to be constant over the 23-year follow-up and showing malignant transformation to squamous cell carcinoma (SCC).
📊
Key Findings & Data:Computed tomography (CT) and magnetic resonance imaging (MRI) findings including diffusion weighted imaging (DWI), 1H+MR spectroscopy (MRS), dynamic susceptibility contrast perfusion (DSC) MRI of EC, and its rare complications are presented together with a review of the literature.
💡
Conclusion & Impact:To our knowledge, no MRS and DSC findings have been reported in the literature yet
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Özet
We report imaging findings of a 64-year-old male patient with a ruptured epidermoid cyst (EC) known to be constant over the 23-year follow-up and showing malignant transformation to squamous cell carcinoma (SCC). Computed tomography (CT) and magnetic resonance imaging (MRI) findings including diffusion weighted imaging (DWI), 1H+MR spectroscopy (MRS), dynamic susceptibility contrast perfusion (DSC) MRI of EC, and its rare complications are presented together with a review of the literature. Fluid-lowattenuated-inversion-recovery (FLAIR) and T1-weighted images with gadolinium are the best sequences together with DWI to show the relationship of the EC, the SCC and the border between. Primary brain SCC enhances mostly ring-like or peripherally, but diffuse enhancement is also possible. To our knowledge, no MRS and DSC findings have been reported in the literature yet
🔖
Cite This Article
OZUTEMİZ, C., ADA, E., ERŞEN, A., ÖZER, E. (2017). Imaging Findings of an Epidermoid Cyst with Malignant Transformation to Squamous Cell Carcinoma. Turkish Neurosurgery, Cilt: 27 - Sayı: 2, 312–315. https://ajindex.com/articles/404523
Abdel Razek AA, Poptani H: MR spectrsocopy of head and neck cancer. Eur J Radiol 82: 982-989, 2013 2. Agarwal S, Rishi A, Suri V, Sharma MC, Satyarthi GD, Garg A, Sarkar C: Primary intracranial squamous cell carcinoma arising in an epidermoid cyst--a case report and review of literature. Clin Neurol Neurosurg 109:888-891, 2007 3. Akar Z, Tanriover N, Tuzgen S, Kafadar AM, Kuday C: Surgical treatment of intracranial epidermoid tumors. Neurol Med Chir 43:275-280, 2003 4. Bulik M, Jancalek R, Vanicek J, Skoch A, Mechl M: Potential of MR spectroscopy for assessment of glioma grading. Clin Neurol Neurosurg 115:146-153, 2013 5. Cirak B, Kiymaz N, Arslanoglu A: Trigeminal neuralgia caused by intracranial epidermoid tumor: Report of a case and review of the different therapeutic modalities. Pain Physician 7:129- 132, 2004 6. Forghani R, Farb RI, Kiehl TR, Bernstein M: Fourth ventricle epidermoid tumor: Radiologic, intraoperative, and pathologic findings. Radiographics 27:1489-1494, 2007 7. Garcia CA, McGarry PA, Rodriguez F: Primary intracranial squamous cell carcinoma of the right cerebellopontine angle. J Neurosurg 54:824-828,1981 8. Ge P, Luo Y, Fu S, Ling F: Recurrent epidermoid cyst with malignant transformation into squamous cell carcinoma. Neurol Med Chir (Tokyo) 49:442-444, 2009 9. Hamlat A, Hua ZF, Saikali S, Laurent JF, Gedouin D, BenHassel M, Guegan Y: Malignant transformation of intra-cranial epithelial cysts: Systematic article review. J Neurooncol 74:187-194, 2005 10. Hao S, Tang J, Wu Z, Zhang L, Zhang J, Wang Z: Natural malignant transformation of an intracranial epidermoid cyst. J Formos Med Assoc 109:390-396, 2010 11. Kano T, Ikota H, Kobayashi S, Iwasa S, Kurosaki S, Wada H: Malignant transformation of an intracranial large epidermoid cyst with leptomeningeal carcinomatosis: Case report. Neurol Med Chir 50:349-353, 2010 12. Nagasawa DT, Choy W, Spasic M, Yew A, Trang A, Garcia HM, Yang I: An analysis of intracranial epidermoid tumors with malignant transformation: Treatment and outcomes. Clin Neurol Neurosurg 115(7): 1071-1078, 2013 13. Nagasawa D, Yew A, Safaee M, Fong B, Gopen Q, Parsa AT, Yang I: Clinical characteristics and diagnostic imaging of epidermoid tumors. J Clin Neurosci 18:1158-1162, 2011 14. Osborn AG, Preece MT: Intracranial cysts: Radiologicpathologic correlation and imaging approach. Radiology 239: 650-664, 2006 15. Pagni F, Brenna A, Leone BE, Vergani F, Isimbaldi G: Malignant epidermoid cyst of the pineal region with lum