Based on our experience with 6 COVID-19-associated ARDS patients on ECMO, we intend to raise awareness regarding thrombotic compli- cations leading to mortality.
📌 3 Key Takeaways
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Objective & Hypothesis:Hypercoagulopathy associated with the novel coronavirus disease (COVID-19) is the leading cause of acute respiratory distress syndrome (ARDS), multiple organ failure, and mortality.
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Key Findings & Data:Extracorporeal membrane oxygenation (ECMO) has been used to manage patients with COVID 19-associated severe respiratory or cardiac failure.
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Conclusion & Impact:Based on our experience with 6 COVID-19-associated ARDS patients on ECMO, we intend to raise awareness regarding thrombotic compli- cations leading to mortality.
🔬Design:Research Article
📍Scope:2020 Verileri
⚙️Variables:Domain Parameters
Özet
Hypercoagulopathy associated with the novel coronavirus disease (COVID-19) is the leading cause of acute respiratory distress syndrome (ARDS), multiple organ failure, and mortality. Extracorporeal membrane oxygenation (ECMO) has been used to manage patients with COVID 19-associated severe respiratory or cardiac failure. In this report, we aim to summarise our experience with deadly thrombotic complications during venovenous ECMO (vvECMO) treatment in 6 patients with COVID-19-associated ARDS between March 19, 2020 and April 20, 2020. Based on our experience with 6 COVID-19-associated ARDS patients on ECMO, we intend to raise awareness regarding thrombotic compli- cations leading to mortality.
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Cite This Article
TUNA, V., ÖZCAN, P. E., ÇELİKSOY, E., POLAT, Ö., ANAKLI, İ., ORHUN, G., ALAY, G., ESEN, F. (2021). Thrombotic Events Related to Extracorporeal Membrane Oxygenation in COVID-19- Associated Severe Acute Respiratory Distress Syndrome. Turkish Journal of Anaesthesiology and Reanimation, Cilt: 49 - Sayı: 6, 480–483. https://ajindex.com/articles/403427
Frantzeskaki F, Armaganidis A, Orfanos SE. Immuno throm- bosis in Acute Respiratory Distress Syndrome: Cross Talks be- tween Inflammation and Coagulation. Respiration. 2017
[Crossref] 2. Ogino Mark T. Extracorporeal Life Support Organization COVID-19 Interim Guidelines. ELSO. Accessed April, 16 2020. https://www.elso.org. 3. Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected. WHO. Accessed February 20, 2020. https://www.who.int/publica- tions/i/item/10665-332299 4. Beyls C, Huette P, Abou-Arab O, Berna P, Mahjoub Y. ECMO for COVID-19 associated severe ARDS and risk of thrombosis. Br J Anaesth. 2020
E260-262. 5. Helms J, Tacquard C, Severac F, et al. High risk of thrombosis in patients with severe SARS-CoV-2 infection: A multicenter prospective cohort study. Intensive Care Med. 2020
[Crossref] 6. Li Q, Guan X, Wu P, et al. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med. 2020
[Crossref] 7. Salerno M, Sessa F, Piscopo A, et al. No Autopsies on COVID-19 Deaths: A Missed Opportunity and the Lockdown of Science. J Clin Med. 2020
[Crossref] 8. Rokkam VRP, Vegunta R, Prudhvi K, et al. “Weighing” the risks and benefits-Thromboprophylaxis challenges in obese COVID-19 patients. Obes Med. 2020
100284. [Crossref] 9. Silvio A. ECMO for ARDS due to COVID-19. Heart Lung. 2020
[Crossref] 10. Kowalewski M, Fina D, Słomka A, et al. COVID-19 and ECMO: the interplay between coagulation and inflammation a narrative review. Critical Care. 2020
[Crossref] 11. Tang N, Li D, Wang X, Sun Z. Abnormal coagulation param- eters are associated with poor prognosis in patients with novel corona virus pneumonia. J Thromb Haemost. 2020
[Crossref] 12. Klok FA, Kruip MJHA, van der Meer NJM, et al. Incidence of thrombotic complications in criticallyill ICU patientswith COVID-19. Thromb Res. 2020
[Crossref] 13. Parzy G, Daviet F, Puech B, et al. Venous Thromboembolism Events Following Venovenous Extracorporeal Membrane Ox- ygenation for Severe Acute Respiratory Syndrome Corona- virus 2 Based on CT Scans. Crit Care Med. 2020
e971-975. [Crossref] 14. Pons S, Fodil S, Azoulay E, Zafranil L. The vascular endothe- lium: The corner stone of organ dysfunction in severe SARS- CoV-2 infection. Crit Care. 2020
[Crossref] 15. Arachchillage DJ, Remmington C, Rosenberg A, et al. Ant