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Journals / Türkderm Türk deri hastalıkları ve frengi arşivi / 2021 / Cilt: 55 - Sayı: 1

Granulomatous skin infections

Granülomatöz deri enfeksiyonları

Didem DİNÇER ROTA
Mehmet Can EMEKSİZ
Pages
1–8
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review aims to summarize granulomatous skin diseases encountered more frequently in our clinical experience because of infectious causes.

📌 3 Key Takeaways

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Objective & Hypothesis:Granulomatous skin disorders are a heterogeneous group of disorders characterized by granuloma formation on histopathology.
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Key Findings & Data:They may be triggered by various stimuli, including infectious and non-infectious stimuli (foreign bodies, malignancy, metabolites, and chemicals), of different etiological origins.
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Conclusion & Impact:This review aims to summarize granulomatous skin diseases encountered more frequently in our clinical experience because of infectious causes.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Granulomatous skin disorders are a heterogeneous group of disorders characterized by granuloma formation on histopathology. They may be triggered by various stimuli, including infectious and non-infectious stimuli (foreign bodies, malignancy, metabolites, and chemicals), of different etiological origins. Although pathophysiological mechanisms are still poorly understood, infectious granuloma formation may occur if the patient’s immune system could not eliminate an agent. Clinically, localized or disseminated infectious granuloma formation can be related to the infectious agent’s pathogenicity or the patient’s immunity. Typical infectious agents causing infectious granulomatous reactions are mycobacteria, fungal infections, or parasites, such as leishmaniasis. This review aims to summarize granulomatous skin diseases encountered more frequently in our clinical experience because of infectious causes.

Özet

Granülomatöz deri hastalıkları histopatolojisinde granülom oluşumu ile karakterize heterojen bir hastalık grubudur. Etiyolojik olarak, enfeksiyöz ve enfeksiyöz olmayan da (yabancı cisim, malignite, metabolitler ve kimyasallar) dahil olmak üzere çok çeşitli uyaranlarla tetiklenebilirler. Her ne kadar patofizyolojik mekanizmalar hala yeterince anlaşılamasa da, hastanın bağışıklık sistemi bir ajanı ortadan kaldıramadığında enfeksiyöz granülom oluşumu meydana gelebilir. Klinik olarak lokalize veya dissemine enfeksiyöz granülom oluşumu, ajanın patojenitesi veya hastanın bağışıklığı ile ilgili olabilir. Enfeksiyöz granülomatöz reaksiyonlara neden olan tipik ajanlar: Mikobakteriler, mantar enfeksiyonları veya layşmanya gibi parazitlerdir. Bu derlemede, klinik deneyimimizde daha sık karşılaşılabilecek enfeksiyöz nedenli granülomatöz deri hastalıklarını özetlemeyi amaçladık.

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Cite This Article

ROTA, D. D., EMEKSİZ, M. C. (2021). Granulomatous skin infections. Türkderm Türk deri hastalıkları ve frengi arşivi, Cilt: 55 - Sayı: 1, 1–8. https://ajindex.com/articles/402216

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