Journals / Türk Fertilite Dergisi / 2005 / Cilt: 13 - Sayı: 1

Perinatal and neonatal outcome of spontaneous twin gestations and twins after assisted reproductive techniques

Spontan ve tedavi ile oluşan ikiz gebeliklerde perinatal ve neonatal sonuçların karşılaştırılması

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52–58
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, different fetal weight and some other neonatal pa¬rameters observed in mono- and di-chorionic twins between spontaneous and ART pregnancies show the importance of placentation.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To compare perinatal and neonatal outcome of twin pregnancies after assisted reproductive techniques (ART) with that of twins conceived spontaneously.
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Key Findings & Data:Materials and Methods: We analyzed diamniotic twin pregnancies that were followed up and delivered between January 1999 and June 2004 in our institution, retrospecti¬vely.
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Conclusion & Impact:However, different fetal weight and some other neonatal pa¬rameters observed in mono- and di-chorionic twins between spontaneous and ART pregnancies show the importance of placentation.
🔬Design:Research Article
📍Scope:2004 Verileri
⚙️Variables:İkizler · Geriyedönük çalışma · Gebelik

Abstract

Objective: To compare perinatal and neonatal outcome of twin pregnancies after assisted reproductive techniques (ART) with that of twins conceived spontaneously. Institution: Trakya University, Faculty of Medicine, Department of Obstetrics and Gynecology, Edirne. Materials and Methods: We analyzed diamniotic twin pregnancies that were followed up and delivered between January 1999 and June 2004 in our institution, retrospecti¬vely. Spontaneous twin pregnancies consisted Group 1 (n=42) and those conceived after ART Group 2 (n=27). In the presence of any bad perinatal or neonatal outcome in any of the twin pairs then that problem was considered positive. Moreover, we investigated perinatal and neonatal outcomes in women with mono- and di-chorionic placenta-tion in a further analysis. Student's t, Mann-Whitney U and chi-square tests were performed for statistical analysis. Results: Patients in Group 1 had higher preterm labor episodes (p=0.046), head circumference (p=0.009) and umbilical cord calcium levels (p=0.015) compared to Group 2. The mean umbilical cord calcium and magnesium levels were elevated, but fetal weight was decreased (1503 + 738.8 vs. 2026.7 + 541.1 gr, p=0.011) in monochorionic twin pregnancies in Group 1 than those in Group 2. In dichorionic twin pregnancies in Group 1 the delivery weeks (32.3 + 3.49 vs. 31.24 + 4.13 weeks, p=0.026), fetal weight (2210 + 449.5 vs. 1803.2 + 566.9 gr, p<0.001), height (44.82 + 3.61 vs. 41.79 + 5.3 cm, p=0.005) and head circumference [32 (21-36) vs. 30.1 (22-36) cm, p=0.002] values were high er compared to those in Group 2. Conclusion: Spontaneous and ART diamhiotic twin pregnancies have similar perinatal and neonatal outcomes. However, different fetal weight and some other neonatal pa¬rameters observed in mono- and di-chorionic twins between spontaneous and ART pregnancies show the importance of placentation.

Özet

Amaç: İkiz gebeliği spontan oluşan ve yardımla üreme teknikleri (YÜT) kullanılarak oluşan hastaların perinatal ve neonatal sonuçlarını karşılaştırmaktır. Çalışmanın Yapıldığı Yer: Trakya Üniversitesi Tıp Fakültesi, Kadın Hastalıkları ve Doğum AD, Edirne. Materyal - Metod: Ocak 1999-Haziran 2004 tarihleri arasında kliniğimizde takip edilip doğumları kliniğimizde gerçekleştiren diamniotik ikiz gebeler retrospektif olarak tarandı. Spontan ikiz gebeler (n=42) Grup 1, YÜT ile olu¬şan ikiz gebeler (n=27) Grup 2'yi oluşturdu. Araştırılan olumsuz perinatal veya neonatal sonuçlardan herhangi birinin ikiz eşlerinden herhangi birinde saptanması durumunda problemin var olduğu kabul edildi. Ayrıca aynı değişkenler için gruplarda monokoryonik ve dikoryonik olanlar ayrılarak tekrar analizler gerçekleştirildi. Sonuçların incelenmesinde Student-t, Mann-Whitney U ve Ki-kare testleri kullanıldı. Bulgular: Grup 1 'de preterm eylem epizodu geçirme oranı (p=0.046), baş çevresi değeri (p=0.009) ve umblikal kord kalsiyum düzeyleri (p=0.015) Grup 2'deki değerlerden yüksek olduğu bulundu. Birinci grubun monokoryonik ikizleriyle Grup 2'nin monokoryonik ikizleri karşılaştırılınca umblikal kord kalsiyum ve magnezyum düzeyleri Grup 1 'de anlamlı olarak yüksek iken, fetal ağırlık anlamlı olarak düşük saptandı (1503 + 738.8 vs. 2026.7 + 541.1 gr, p=0.011). Grup l'deki dikoryonik gebelerin doğum haftası (32.3 + 3.49 vs. 31.24 + 4.13 hafta, p=0.026); doğum ağır¬lıkları (2210 + 449.5 vs. 1803.2 + 566.9 gr, p< 0.001), boy¬ları (44.82 + 3.61 vs. 41.79 + 5.3 cm, p= 0.005) ve baş çevresi değerleri [32 (21-36) vs. 30.1 (22-36) cm, p=0.002] Grup 2'dekilerden anlamlı olarak fazlaydı Sonuçlar: Spontan ve YÜT kullanılarak oluşan diamniotik ikiz gebeliklerin perinatal ve neonatal sonuçları benzerdir. Diğer yandan, mono- ve dikoryonik ikiz gebeler incelendiğinde doğum ağırlıklarının ve bazı neonatal para¬metrelerin farklı olması plasentasyonun önemini vurgulamaktadır.

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Cite This Article

SAYIN, N. C., VAROL, F. G., ARDA, S., VATANSEVER, Ü., ACUNAŞ, B., ÖMÜRLÜ, İ. K. (2005). Perinatal and neonatal outcome of spontaneous twin gestations and twins after assisted reproductive techniques. Türk Fertilite Dergisi, Cilt: 13 - Sayı: 1, 52–58. https://ajindex.com/articles/402134

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References (15)

  1. Conde-Agudelo A, Belizan JM, Lindmark G. Maternal morbidity and mortality associated with multiple gestations. Obstet Gynecol 2000; 95: 899-904
  2. Moise J, Laor A, Armon Y, Gur I, Gale R. The outcome of twin pregnancies after IVF. Hum Reprod 1998; 13: 1702-5
  3. Olivennes F, Fanchin R, Ledee N, Righini C, Kadoch IJ, Frydman R. Perinatal outcome and development studies on children born after IVF. Hum Reprod 2002; 8: 117-28
  4. Helmerhorst FM, Perquin DAM, Donker D, Keirse MJNC. Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies. BMJ 2004; 328: 261-5
  5. Kessler L, Lancet M, Borenstein R, Steinmetz A. The problem of the older primipara. Obstet Gynecol 1980; 56: 165-9
  6. Tan SL, Doyle P, Campbell S, et al. Obstetric outcome of in vitro fertilization pregnancies compared with normally conceived pregnancies. Am J Obstet Gynecol 1992; 167: 778-84
  7. Olivennes F, Kadhel P, Rufat P, Fanchin R, Fernandez H, Frydman R. Perinatal outcome of twin pregnancies obtained after in-vitro fertilization: comparison with twin pregnancies obtained spontaneously or after ovarian stimulation. Fertil Steril 1996; 66: 105-9
  8. Bernasko J, Lynch L, Lapinski R, Berkowitz RL. Twin pregnancies conceived by assisted reproductive techniques: maternal and neonatal outcomes. Obstet Gynecol 1997; 89: 368-2
  9. Dhont M, DeSutter P, Ruyssinck G, Martens G, Bekaert A. Perinatal outcome of pregnancies after assisted reproduction: a case control study. Am J Obstet Gynecol 1999; 181: 688-95
  10. Lambalk CB, van Hooff M. Natural versus induced twinning and pregnancy outcome: a Dutch nationwide survey of primiparous dizygotic twin deliveries. Fertil Steril 2001; 75:731-6
  11. Zuppa AA, Maragliano G, Scapillati ME, Crescimbini B, Tortorolo G. Neonatal outcome of spontaneous and assisted twin pregnancies. Eur J Obstet Gynecol Reprod Biol 2001; 95: 68-72
  12. Zaib-un-Nisa S, Ghazal-Aswad S, Badrinath P. Outcome of twin pregnancies after assisted reproductive techniquesa comparative study. Eur J Obstet Gynecol Reprod Biol 2003; 109: 51-4
  13. Petersen K, Hornnes PJ, Ellingsen S, et al. Perinatal outcome after in vitro fertilisation. Acta Obstet Gynecol Scand 1995; 74: 129-31
  14. Koudstaal J, Bruinse HW, Helmerhorst FM, Vermeiden JP, Willemsen WN, Visser GH. Obstetric outcome of twin pregnancies after in-vitro fertilization: a matched control study in four Dutch university hospitals. Hum Reprod 2000; 15: 935-40
  15. Kovacs BW, Kirschbau