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Journals / Middle East Journal of Science / 2021 / Cilt: 7 - Sayı: 2

THREE MSA TOOLS ANALYSIS in DNA and PROTEIN DATASETS

Fırat AŞIR
Tuğcan KORAK
Özgür ÖZTÜRK
Pages
89–99
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Result show that for both protein and DNA dataset, MAFFT may be more useful among three of MSA tool used.

📌 3 Key Takeaways

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Objective & Hypothesis:Multiple sequence alignment (MSA) is used to align three or more sequences of DNA, RNA and protein.
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Key Findings & Data:In this article three MSA tools; CLUSTALW, SAGA and MAFFT are used for five datasets BALiBASE_R9, DIRMBASE, SABmark and additionally constructed DNABali and ProteinBali for alignment.
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Conclusion & Impact:Result show that for both protein and DNA dataset, MAFFT may be more useful among three of MSA tool used.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:multiple sequence alignment · MAFFT · SAGA

Abstract

Multiple sequence alignment (MSA) is used to align three or more sequences of DNA, RNA and protein. It is prominent for constructing phylogenetic trees and evolutionary relationships between sequences with regard to similarities and dissimilarities. Variety of multiple sequence alignment tools are available online, each having different methods and parameters to align sequences. In this article three MSA tools; CLUSTALW, SAGA and MAFFT are used for five datasets BALiBASE_R9, DIRMBASE, SABmark and additionally constructed DNABali and ProteinBali for alignment. Result show that for both protein and DNA dataset, MAFFT may be more useful among three of MSA tool used.

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Cite This Article

AŞIR, F., KORAK, T., ÖZTÜRK, Ö. (2021). THREE MSA TOOLS ANALYSIS in DNA and PROTEIN DATASETS. Middle East Journal of Science, Cilt: 7 - Sayı: 2, 89–99. https://ajindex.com/articles/401716

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