Journals / Turkish Journal of Veterinary and Animal Sciences / 1999 / Cilt: 23 - Sayı: 5

Role of Vitamin E in Decreasing the Toxic Effect of Digoxin

Pages
445–450
Publication Date
1999-05-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was found that digoxin-only treatment caused a sinusoidal tachicardia without changing the durations or amplitudes of any wave on the trace.

📌 3 Key Takeaways

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Objective & Hypothesis:This experiment was carried out to evaluate the role of vitamin E in decreasing the toxic effect of digoxin.
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Key Findings & Data:Recordings were obtained before and 24 hours after treatments.
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Conclusion & Impact:It was found that digoxin-only treatment caused a sinusoidal tachicardia without changing the durations or amplitudes of any wave on the trace.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Digoxin · Vitamin E · Rabbits

Abstract

This experiment was carried out to evaluate the role of vitamin E in decreasing the toxic effect of digoxin. Electrocardiographic recordings of New Zealand rabbits which were treated with digoxin-only or digoxin+vitamin E were used. Recordings were obtained before and 24 hours after treatments. It was found that digoxin-only treatment caused a sinusoidal tachicardia without changing the durations or amplitudes of any wave on the trace. However, digoxin+vitamin E treatment did not produce any increase in heart rate. It was concluded that vitamin E injection along with digoxin injection might lower the toxic effect of digoxin. More studies are needed to convince these findings.

Özet

This experiment was carried out to evaluate the role of vitamin E in decreasing the toxic effect of digoxin. Electrocardiographic recordings of New Zealand rabbits which were treated with digoxin-only or digoxin+vitamin E were used. Recordings were obtained before and 24 hours after treatments. It was found that digoxin-only treatment caused a sinusoidal tachicardia without changing the durations or amplitudes of any wave on the trace. However, digoxin+vitamin E treatment did not produce any increase in heart rate. It was concluded that vitamin E injection along with digoxin injection might lower the toxic effect of digoxin. More studies are needed to convince these findings.

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Cite This Article

MERAL, İ., BAYDAŞ, B., BAYIROĞLU, F. (1999). Role of Vitamin E in Decreasing the Toxic Effect of Digoxin. Turkish Journal of Veterinary and Animal Sciences, Cilt: 23 - Sayı: 5, 445–450. https://ajindex.com/articles/400712

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