Journals / Şişli Etfal Hastanesi Tıp Bülteni / 2021 / Cilt: 55 - Sayı: 4

The Rate of Coronary Angiography Refusal in Older Patients with Non-ST Elevation Acute Coronary Syndrome and Its Impact on All-Cause Mortality

Pages
[532]–537
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Factors affecting patient behavior and the decision-making process should be explored.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Significant number older patients with acute coronary syndrome (ACS) cannot undergo coronary angiography (CAG) due to various comorbidities.
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Key Findings & Data:We wanted to assess CAG refusal rate and its impact on all-cause mortality in older patients with non-ST elevation acute myocardial infarction.
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Conclusion & Impact:Factors affecting patient behavior and the decision-making process should be explored.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objectives: Significant number older patients with acute coronary syndrome (ACS) cannot undergo coronary angiography (CAG) due to various comorbidities. Patient’s refusal of invasive procedures is common among old patients and has not been thoroughly investigated in the context of ACS. We wanted to assess CAG refusal rate and its impact on all-cause mortality in older patients with non-ST elevation acute myocardial infarction. Methods: In this retrospective study, patients over 75 years of age admitted with acute non-ST elevation ACS were included in the study. Patients were divided into three groups based on the treatment strategy; Group 1: Those who underwent CAG; Group 2: Refused; and Group 3: Deemed unsuitable for procedure due to severe comorbidities. The primary outcomes were to assess the patient refusal rate and its impact on all-cause mortality. Results: The study included 201 elderly patients. Eighty-two (41%) patients did not undergo CAG and of those, 48 (24%) had severe comorbidities, and 34 (17%) refused the procedure. The in-hospital mortality for patients who underwent, refused, or could not undergo CAG was 5.0%, 0%, and 16.7% (p<0.01); 30-day mortality 8.5%, 9.1%, and 25% (p=0.01); and long-term mortality was 20.2%, 35.3%, and 47.9% (p<0.01), respectively. The median follow-up was 12 months. Hazard ratio of treatment refusal for longterm mortality was 1.97 (1.02–3.87, 95% CI). Conclusion: Substantial number of elderly patients with ACS refuses to undergo CAG and this leads to increased mortality. Factors affecting patient behavior and the decision-making process should be explored.

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Cite This Article

KESKİN, K., ÇETİNKAL, G., SER, Ö. S., SIĞIRCI, S., GÜRDAL, A., KILIÇKESMEZ, K. O. (2021). The Rate of Coronary Angiography Refusal in Older Patients with Non-ST Elevation Acute Coronary Syndrome and Its Impact on All-Cause Mortality. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 55 - Sayı: 4, [532]–537. https://ajindex.com/articles/399595

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References (9)

  1. Mathers CD, Stevens GA, Boerma T, White RA, Tobias MI. Causes of international increases in older age life expectancy. Lancet 2015;385:540–8
  2. Mehta H, Sacrinty M, Johnson D, St Clair M, Paladenech C, Robinson K. Comparison of usefulness of secondary prevention of coronary disease in patients 3. Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti Fet al; ESC Scientific Document Group. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC). Eur Heart J 2016;37:267–315
  3. Authors/Task Force members, Windecker S, Kolh P, Alfonso F, Collet JP, Cremer J, Falk V, et al. 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J 2014;35:2541–619
  4. Shanmugam VB, Harper R, Meredith I, Malaiapan Y, Psaltis PJ. An overview of PCI in the very elderly. J Geriatr Cardiol 2015;12:174– 84
  5. Gharacholou SM, Alexander KP, Chen AY, Wang TY, Melloni C, Gibler WB, et al. Implications and reasons for the lack of use of reperfusion therapy in patients with ST-segment elevation myocardial infarction: findings from the CRUSADE initiative. Am Heart J 2010;159:757–63
  6. Leonardi S, Chen AY, Gharacholou SM, Wang TY, de Lemos JA, Saucedo JF, et al. Limitations of using cardiac catheterization rates to assess the quality of care for patients with non-ST-segment elevation myocardial infarction. Am Heart J 2012;164:502–8
  7. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, et al; Acute Kidney Injury Network. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007;11:R31
  8. Garg A, Garg L, Agarwal M, Rout A, Raheja H, Agrawal S, et al. Routine invasive versus selective invasive strategy in elderly patients older than 75 years with Non-ST-segment elevation acute coronary syndrome: a systematic review and meta-analysis. Mayo Clin Proc 2018;93:436–44
  9. Dégano IR, Subirana I, Fusco D, Tavazzi L, Kirchberger I, Farmakis D, et al; EUROTRACS investigators. Percutaneous corona