The 10-yearoverall survival rate was 86%.CONCLUSION: Meningiomas in the pediatric age group are surgically treatable tumors with fairly good outcomes.
📌 3 Key Takeaways
🎯
Objective & Hypothesis:AIM: To evaluate the long-term outcomes and prognostic variables in a surgical cohort of pediatric meningiomas treated in a singleinstitution.MATERIAL and METHODS: Medical records and follow-up notes of 23 pediatric patients aged 3) during the last follow-up assessment.
📊
Key Findings & Data:Ten patients (43.5%) had relapse.
💡
Conclusion & Impact:The 10-yearoverall survival rate was 86%.CONCLUSION: Meningiomas in the pediatric age group are surgically treatable tumors with fairly good outcomes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Özet
AIM: To evaluate the long-term outcomes and prognostic variables in a surgical cohort of pediatric meningiomas treated in a singleinstitution.MATERIAL and METHODS: Medical records and follow-up notes of 23 pediatric patients aged 3) during the last follow-up assessment. Ten patients (43.5%) had relapse. In univariateanalysis, low histological grade (p=0.030) and gross total resection (p=0.024) were associated with favorable outcome. The 10-yearoverall survival rate was 86%.CONCLUSION: Meningiomas in the pediatric age group are surgically treatable tumors with fairly good outcomes. However,relapses are common even for low-grade tumors; therefore, long-term surveillance and aggressive treatment are needed.
🔖
Cite This Article
IŞIKAY, İ., HANALIOGLU, S., NARİN, F., BASAR, I., BİLGİNER, B. (2020). Long-Term Outcomes of Pediatric Meningioma Surgery: Single Center Experience with 23 Patients. Turkish Neurosurgery, Cilt: 30 - Sayı: 1, 124–133. https://ajindex.com/articles/399184
Alexiou GA, Mpairamidis E, Psarros A, Sfakianos G, Prodromou N: Intracranial meningiomas in children: Report of 8 cases. Pediatr Neurosurg 44:373-375, 2008 2. Arivazhagan A, Devi BI, Kolluri SV, Abraham RG, Sampath S, Chandramouli BA: Pediatric intracranial meningiomas-do they differ from their counterparts in adults? Pediatr Neurosurg 44:43-48, 2008 3. Bilginer B, Hanalioglu S, Turk CC, Narin F, Oguz KK, Soylemezoglu F, Akalan N: Is the knowledge pertaining to adult glioblastomas enough for pediatric cases? prognostic factors in childhood. Turk Neurosurg 27:279-288, 2017 4. Bilginer B, Turk CC, Narin F, Hazer B, Hanalioglu S, Oguz KK, Soylemezoglu F, Akalan N: De novo formation of brain tumors in pediatric population following therapeutic cranial irradiation. Childs Nerv Syst 31:893-899, 2015 5. Celtikci E, Kaymaz AM, Akgul G, Karaaslan B, Emmez OH, Borcek A: Retrospective analysis of 449 intracranial meningioma patients operated between 2007 and 2013 at a single institute. Turk Neurosurg 28:1-6, 2018 6. El Beltagy MA, Enayet AE, Atteya MME, Reda M, Refaat A, Taha H, Ahmed S, Abdelaziz A: Management of pediatric CNS meningiomas: CCHE-57357 experience in 39 cases. Childs Nerv Syst 35:1323-1331, 2019 7. Fan MC, Fang W, Liu K, Wang C, Deng WS, Sun P, Tang WZ: Paediatric intracranial meningiomas: Eight-year experience with 32 cases. Chinese Neurosurgical Journal, 2017 8. Gao X, Zhang R, Mao Y, Wang Y: Childhood and juvenile meningiomas. Childs Nerv Syst 25:1571-1580, 2009 9. Greene S, Nair N, Ojemann JG, Ellenbogen RG, Avellino AM: Meningiomas in children. Pediatr Neurosurg 44:9-13, 2008 10. Grossbach AJ, Mahaney KB, Menezes AH: Pediatric meningiomas: 65-year experience at a single institution. J Neurosurg Pediatr 20:42-50, 2017 11. Huntoon K, Pluto CP, Ruess L, Boue DR, Pierson CR, Rusin JA, Leonard J: Sporadic pediatric meningiomas: A neuroradiological and neuropathological study of 15 cases. J Neurosurg Pediatr 20:141-148, 2017 12. Im SH, Wang KC, Kim SK, Oh CW, Kim DG, Hong SK, Kim NR, Chi JG, Cho BK: Childhood meningioma: Unusual location, atypical radiological findings, and favorable treatment outcome. Childs Nerv Syst 17:656-662, 2001 13. Isikay I, Hanalioglu S, Basar I, Narin F, Bilginer B: Survival benefit with gross total resection and adjuvant radiotherapy in childhood atypical teratoid/rhabdoid tumors: Results of a single-center cohort of 27 cases. Turk Neurosurg 29:689-697, 2019 14. Kotecha RS, Junckerstorff RC, Lee S, Cole CH, Gottardo NG: Pe