Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2019 / Cilt: 53 - Sayı: 3

İdiopathic palmoplantar filiform hyperkeratosis succesfully treated with systemic isotretinoin

Sistemik isotretinoin ile başarılı bir şekilde tedavi edilen idiyopatik palmoplantar filiform hiperkeratozis

Pages
119–121
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was observed that the lesions almost completely retreat after 2 months of treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:Filiform hyperkeratosis is a disease that often involves the palmoplantar region and rarely can involve other parts of the body.
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Key Findings & Data:An 18-year-old woman was admitted to our clinic with the complaints of dermatological skin extensions on her hands and feet for 6 months.
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Conclusion & Impact:It was observed that the lesions almost completely retreat after 2 months of treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Filiform hyperkeratosis is a disease that often involves the palmoplantar region and rarely can involve other parts of the body. It is usually associated with malignancies or systemic diseases, but rarely it can also occur as idiopathic. An 18-year-old woman was admitted to our clinic with the complaints of dermatological skin extensions on her hands and feet for 6 months. She stated that there was no contact of any chemical agent and did not receive any topical or systemic treatment for these complaints. The patient was otherwise healthy and her past medical history and family history were non‐contributory. The systemic examination was evaluated as normal. In dermatologic examination, painful, filiform papules were observed in both palmoplantar regions. Hyperkeratosis and focal regular acanthosis was detected in the skin biopsy from the palmar region of the patient. There was no individual with a similar lesion in in her family, and no pathological findings were found in biochemistry, hemogram and tumor markers. Patient was evaluated as idiopathic palmoplantar filiform like hyperkeratosis with these findings and 20 mg/day isotretinoin treatment was started. It was observed that the lesions almost completely retreat after 2 months of treatment.

Özet

Filiform hiperkeratoz özellikle palmoplantar tutulum yapan ve nadiren vücudun diğer bölgelerini de tutabilen bir hastalıktır. Genelliklemaligniteler veya sistemik hastalıklar ile birlikte görülmekte olup nadiren idiyopatik olarak da gelişebilmektedir. On sekiz yaşında kadın hasta 6aydır el ve ayaklarında dikensi karakterde deri uzantıları ile kliniğimize başvurdu. Öncesinde herhangi bir kontakt madde temasının olmadığını,bu şikayetlerine yönelik herhangi bir topikal veya sistemik tedavi almadığını ifade etti. Özgeçmişinde ve soygeçmişinde herhangi bir özellikyoktu. Sistem muayenesi normal olarak değerlendirildi. Dermatolojik muayenesinde; bilateral palmoplantar bölgede yaygın filiform karakterdehassas papüller izlendi. Hastanın palmar bölgesindeki lezyondan alınan deri biyopsisinde; yüzeyde hiperkeratoz, fokal regüler akantoz gösterenepidermis görüldü. Bu olguda ailesinde benzer lezyonu olan birey yoktu ve yapılan radyolojik incelemelerinde, biyokimya, hemogram vetümör belirteçlerinde herhangi bir patolojik bulguya rastlanmadı. Böylece hasta edinsel idiyopatik palmoplantar filiform hiperkeratoz olarakdeğerlendirildi ve 20 mg/gün isotretinoin tedavisi başlandı. Tedaviden 2 ay sonra lezyonlarda tama yakın gerileme gözlendi.

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Cite This Article

KORKMAZ, S., ERTURAN, İ., FİLİZ, B., KARAHAN, N., CİRİŞ, İ. M., YILDIRIM, M. (2019). İdiopathic palmoplantar filiform hyperkeratosis succesfully treated with systemic isotretinoin. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 53 - Sayı: 3, 119–121. https://ajindex.com/articles/399025

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