Journals / Turkish Journal of Medical Sciences / 2013 / Cilt: 43 - Sayı: 6

Parathyroid hormone and optimal vitamin D status in postmenopausal women

Pages
990–994
Publication Date
2013-06-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

PTH levels were higher than 75 pg/dL in 52 patients, and 65.4% of those patients (n = 34) had vitamin D insufficiency (

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Low serum vitamin D and calcium levels as well as high parathyroid hormone (PTH) levels are the most important risk factors in osteoporosis.
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Key Findings & Data:Materials and methods: A total of 197 postmenopausal women who were at the menopausal period for at least 1 year and who had body mass indexes (BMIs) 70 years).
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Conclusion & Impact:PTH levels were higher than 75 pg/dL in 52 patients, and 65.4% of those patients (n = 34) had vitamin D insufficiency (
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Key words: Osteoporosis · menopause · vitamin D

Abstract

Low serum vitamin D and calcium levels as well as high parathyroid hormone (PTH) levels are the most important risk factors in osteoporosis. The aim of our study was to estimate the optimal vitamin D status needed to prevent a rise in PTH concentrations in postmenopausal women. Materials and methods: A total of 197 postmenopausal women who were at the menopausal period for at least 1 year and who had body mass indexes (BMIs) 70 years). Results: The mean age of patients was 60.8 ± 10.9 years. Serum 25-hydroxyvitamin D3 [25(OH)D3] levels were lower than 10 ng/mL in 94 patients (47.7%) and lower than 20 ng/mL in 167 (84.8%) patients. The mean vitamin D level was lowest in group 2 (51-60 years), but the difference was not statistically significant (P = 0.57). PTH levels were higher than 75 pg/dL in 52 patients, and 65.4% of those patients (n = 34) had vitamin D insufficiency (

Özet

Low serum vitamin D and calcium levels as well as high parathyroid hormone (PTH) levels are the most important risk factors in osteoporosis. The aim of our study was to estimate the optimal vitamin D status needed to prevent a rise in PTH concentrations in postmenopausal women. Materials and methods: A total of 197 postmenopausal women who were at the menopausal period for at least 1 year and who had body mass indexes (BMIs) 70 years). Results: The mean age of patients was 60.8 ± 10.9 years. Serum 25-hydroxyvitamin D3 [25(OH)D3] levels were lower than 10 ng/mL in 94 patients (47.7%) and lower than 20 ng/mL in 167 (84.8%) patients. The mean vitamin D level was lowest in group 2 (51-60 years), but the difference was not statistically significant (P = 0.57). PTH levels were higher than 75 pg/dL in 52 patients, and 65.4% of those patients (n = 34) had vitamin D insufficiency (

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Cite This Article

YIKILKAN, H., AYPAK, C., GÖRPELİOĞLU, S., DİCLE, M., ÖNDER, Ö. (2013). Parathyroid hormone and optimal vitamin D status in postmenopausal women. Turkish Journal of Medical Sciences, Cilt: 43 - Sayı: 6, 990–994. https://ajindex.com/articles/398172

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References (14)

  1. Delmas PD, Fraser M. Strong bones in later life: luxury or necessity? Bull World Health Organ 1999; 77: 416–422.
  2. Odabaşı E, Turan M, Tekbaş F, Kutlu M. Evaluation of osteoporotic fractures in a group of Turkish women. Turkish J Med Sci 2009; 39: 21–28.
  3. Rodriguez-Martinez MA, Garcia-Cohen EC. Role of Ca(2+) and vitamin D in the prevention and treatment of osteoporosis. Pharmacol Ther 2002; 93: 37–49.
  4. Turhan NÖ, Bolkan F, Duvan Cİ, Ardıçoğlu Y. The effect of isoflavones on bone mass and bone remodelling markers in postmenopausal women. Turk J Med Sci 2008; 38: 145–152.
  5. Riggs BL, Khosla S, Melton U. A unitary model for involutional osteoporosis: estrogen deficiency causes both types I and II osteoporosis in post-menopausal women and osteoporosis in post-menopausal women and contributes to bone 1055 in aging men. J Bone Miner Res 1998; 13: 763–773.
  6. Johnston CC, Slemenda CW. Changes in skeletal tissue during the aging process. Nutr Rev 1992; 50: 385–387.
  7. Lowe NM, Ellahi B, Bano Q, Bangash SA, Mitra SR, Zaman M. Dietary calcium intake, vitamin D status, and bone health in postmenopausal women in rural Pakistan. J Health Popul Nutr 2011; 29: 465–470. Heaney RP. Calcium intake requirement and bone mass in the elderly. J Lab Clin Med 1982; 100: 309–312.
  8. Nordin BE, Need AG, Morris HA, Horowitz M. New approaches to the problems of osteoporosis. Clin Orthop Relat Res 1985; 200: 181–197.
  9. Mawer EB, Davies M. Vitamin D nutrition and bone disease in adults. Rev Endocrin Metabol Disord 2001; 2: 153–164.
  10. Pfeifer M, Begerow B, Minne HW, Schlotthauer T, Pospeschill M, Scholz M, Lazarescu AD, Pollähne W. Vitamin D status, trunk muscle strength, body sway, falls, and fractures among 237 postmenopausal women with osteoporosis. Experiment Clin Endocrin Diabet 2001; 109: 87–92.
  11. Ozkurt B, Ozkurt ZN, Altay M, Aktekin CN, Cağlayan O, Tabak Y. The relationship between serum adiponectin level and anthropometry, bone mass, osteoporotic fracture risk in postmenopausal women. Joint Diseases and Related Surgery 2009; 20: 78–84.
  12. Bandeira F, Griz L, Dreyer P, Eufrazino C, Bandeira C, Freese E. Vitamin D deficiency: a global perspective. Arq Bras Endocrinol Metab 2006; 50: 640–646.
  13. Reid IR, Ames R, Evans MC, Sharpe S, Gamble G, France JT, Lim TM, Cundy TF. Determinants of total body and regional one mineral density in normal postmenopausal women—a key role for fat mass. J Clin Endocrinol Metab 1992; 75: 45–51.
  14. Sosa Henriquez M, Gomez de Tejada Romero MJ. Evidenced based medicine and drugs app