Journals / Gıda / 2012 / Cilt: 37 - Sayı: 5

Risk Assessment Studies of Acrylamide in Foods (Turkish with English Abstract)

Gıdalarda Akrilamid Risk Değerlendirme Çalışmaları

Journal
Gıda
Pages
287–294
Publication Date
2012-10-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, risk assessment studies of acrylamide are researched in the light of the literature and the results are evaluated.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Acrylamide, classified as group 2A (probably carcinogenic to humans) by the International Agency for Research on Cancer (IARC), is a processing contaminant which is generated as a result of the application of heat treatment especially to reducing sugar and asparagine rich foods.
📊
Key Findings & Data:This contaminant, determined in commonly consumed foods in daily diet at various levels, has become the centre of attraction of many food and health authorities due to the known potential adverse health effects.
💡
Conclusion & Impact:In this review, risk assessment studies of acrylamide are researched in the light of the literature and the results are evaluated.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Akrilamid · gıda · risk değerlendirme

Abstract

Acrylamide, classified as group 2A (probably carcinogenic to humans) by the International Agency for Research on Cancer (IARC), is a processing contaminant which is generated as a result of the application of heat treatment especially to reducing sugar and asparagine rich foods. This contaminant, determined in commonly consumed foods in daily diet at various levels, has become the centre of attraction of many food and health authorities due to the known potential adverse health effects. Within this scope, risk assessments studies are performed with the aim of identifying existing risks originating from acrylamide and improving the plans and policies in the context of these risks. Risk assessment includes the hazard identification and characterization step which researches the biochemical properties of acrylamide and the arising toxicological effects depending on these properties; exposure assessment step which investigates the levels of daily acrylamide intake per kilogram of body weight of indivuals; and risk characterization step which brings all the previous steps together and evaluates the potential risks for the population or sub-groups in the population qualitatively and quantitatively. In this review, risk assessment studies of acrylamide are researched in the light of the literature and the results are evaluated.

Özet

Uluslararası Kanser Araştırma Ajansı (IARC) tarafından Grup 2A (insanlar için olası kanserojen) olarak sınıflandırılan akrilamid, özellikle indirgen şeker ve asparajin içeriği yüksek gıdalara ısıl işlem uygulanmasının bir sonucu olarak oluşan bir proses kontaminantıdır. Günlük diyette sıklıkla tüketilen gıdalarda çeşitli düzeylerde tespit edilen bu kontaminant, bilinen potansiyel sağlık etkilerinden dolayı pek çok gıda ve sağlık otoritesinin ilgi odağı olmuştur. Bu kapsamda, akrilamid kaynaklı mevcut risklerin belirlenmesi ve bu riskler bağlamında plan ve politikaların geliştirilmesi amacıyla risk değerlendirme çalışmaları yapılmaktadır. Risk değerlendirme; akrilamidin biyokimyasal özelliklerinin ve bu özelliklere bağlı olarak oluşabilecek toksik etkilerinin incelendiği tehlikenin tanımlanması ve karakterize edilmesi aşamasını, bireylerin günlük olarak vücut ağırlıkları başına akrilamid alım düzeylerinin incelendiği maruziyet değerlendirme aşamasını ve tüm bu aşamaları bir araya getiren ve toplum veya toplumdaki özel gruplar için olası riskleri nitel ya da nicel olarak değerlendiren risk karakterizasyonu aşamasını içermektedir. Bu derlemede literatür bilgileri ışığında akrilamidin risk değerlendirme çalışmaları incelenerek sonuçlar değerlendirilmiştir.

🔖

Cite This Article

BOYACI, C. P., CENGİZ, M. F. (2012). Risk Assessment Studies of Acrylamide in Foods (Turkish with English Abstract). Gıda, Cilt: 37 - Sayı: 5, 287–294. https://ajindex.com/articles/39565

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (7)

  1. Tareke E, Rydberg P, Karlsson P, Eriksson S, Tornqvist M. 2002. Analysis of acrylamide, a carcinogen formed in heated foodstuffs. J Agric Food Chem, 50 (17): 4998-5006.
  2. Boroushaki MT, Nikkhah E, Kazemi A, Oskooei M, Raters M. 2010. Determination of acrylamide level in popular Iranian brands of potato and corn products. Food Chem Toxicol, 48 (10): 2528-2584.
  3. Claus A, Carle R, Schieber A. 2008. Acrylamide in cereal products: A review. J. Cereal Sci, 47: 118-133. 4. Tamer C, Karaman B. 2006. Gıdalarda akrilamid oluşumu ve insan sağlığı üzerine etkileri. GIDA, 31 (4): 195-199. Parzefall W. 2008. Minireview on the toxicity of dietary acrylamide. Food Chem Toxicol, 46: 1360-1364.
  4. Tardiff RG, Gargas ML, Kirman CR, Carson ML, Sweeney LM. 2010. Estimation of safe dietary intake levels of acrylamide for humans. Food Chem Toxicol, 48 (2): 658-667.
  5. Delgado-Andrade C, Mesías M, Morales FJ, Seiquer I, Navarro MP. 2011.Assessment of acrylamide intake of Spanish boys aged 11-14 years consuming a traditional and balanced diet. LWT - Food Sci and Tech, 46 (1): 16-22.
  6. Kütting B, Schettgen T, Schwegler U, Fromme H, Uter W, Angerer J, Drexler H. 2009. Acrylamide as environmental noxious agent. Int J of Hyg and Env Heal, 212 (5): 470-480.
  7. Claeys W, Baert K, Mestdagh F, Vercammen J, Daenens P, Meulenaer B, Maghuin-Rogister G, Huyghebaert A. 2010. Assessment of the acrylamide intake of the Belgian population and the effect of mitigation strategies. Food Addit Contam, 27 (9): 1199-1207. NRC (National Research Council). 1983. Risk Assessment in the Federal Government: Managing the Process, Committee on the Institutional Means for Assessment of Risks to Public Health, Commission on Life Sciences, NRC, Washington, DC, National Academy Press. USEPA (U.S. Environmental Protection Agency). 2010. Toxicological review of Acrylamide. EPA/635/R-07/009F. Washington, DC, 459 p. Young JF, Luecke RH, Doerge DR. 2007. Physiologically based pharmacokinetic/ pharmacodynamic model for acrylamide and its metabolites in mice, rats, and humans. Chem Res Toxicol, 20: 388-399. EC SCF (European Commission - Scientific Committee on Food). 2002. Opinion of the Scientific Committee on Food on new findings regarding the presence of acrylamide in food, Brussels, Belgium, 16 p. 14. Besaratinia A, Pfeifer GP. 2007. A review of mechanisms of acrylamide carcinogenicity. Carcin, 28 (3): 519-528. Exon JH. 2006. A review of the toxicology of acrylamide. J Toxicol Environ Health, 9: 397-412. 16. Zhu YJ, Zeng T, Zhu Y