Journals / Hayvansal Üretim / 2021 / Cilt: 62 - Sayı: 2

Effects of ACTH and Acute Heat Stress on Oxidative Stress in an Early Environmentally Enriched Broilers

Erken Yaşta Zenginleştirilmiş Çevrede Yetiştirilen Etlik Piliçlerde ACTH ve Akut Isı Stresinin Oksidatif Stres Üzerine Etkileri

Pages
93–98
Publication Date
2021-12-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was concluded that rearing in an enrichment environment beginning from early ages can be recommended as a useful method for adaptation to stress.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, the effects of early (≤21. d) environmental enrichment and acute heat stress on oxidative stress were investigated and the ability of broilers to cope with later heat stress and adrenocorticotropic hormone (ACTH) treatments were determined.
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Key Findings & Data:Material and Methods: Six hundred day-old chicks were randomly assigned to 3 experimental groups as a control (C), environmental enrichment (EE) and environmental enrichment plus heat stress (EE+HS).
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Conclusion & Impact:It was concluded that rearing in an enrichment environment beginning from early ages can be recommended as a useful method for adaptation to stress.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:ACTH · akut ısı stresi · etlik piliç

Abstract

Objective: In this study, the effects of early (≤21. d) environmental enrichment and acute heat stress on oxidative stress were investigated and the ability of broilers to cope with later heat stress and adrenocorticotropic hormone (ACTH) treatments were determined. Material and Methods: Six hundred day-old chicks were randomly assigned to 3 experimental groups as a control (C), environmental enrichment (EE) and environmental enrichment plus heat stress (EE+HS). At 21 d of age, broilers in EE+HS group were exposed to acute heat stress at 38±1 ˚C for 3 h. On the day 42nd, C and EE groups were divided into 2 subgroups as well Control, Control+ACTH, EE, EE+ACTH. While 50 IU ACTH/kg body weight was injected to Control+ACTH and EE+ACTH groups intramuscularly, broilers in C, EE and EE+HS groups were exposed to heat stress and oxidative stress responses of birds were evaluated. Results: Environmental enrichment did not affect blood corticosterone (CORT), malondialdehyde (MDA) and liver superoxide dismutase (SOD) levels of broilers at 21 d of age. ACTH treatment caused a significant decrease in CORT and MDA concentrations in EE broilers compared to the control group. Exposing birds to heat stress (42nd day) significantly increased CORT, MDA and decreased liver SOD levels in control as compared to EE and EE+HS groups. No significant differences were found in the SOD serum levels between groups. ACTH treatment caused more stress reactions than heat stress. Conclusion: The results obtained from this study show that exposure of broilers to acute heat stress or treatment of experimental adrenocorticotropic hormone causes preferable reactions in oxidative metabolism. It was concluded that rearing in an enrichment environment beginning from early ages can be recommended as a useful method for adaptation to stress.

Özet

Amaç: Bu çalışmada, erken yaşta uygulanan çevresel zenginleştirme ve akut ısı stresinin (21. gün) oksidatif stres üzerindeki etkileri araştırılmış ve etlik piliçlerin daha sonraki ısı stresi ve adrenokortikotropik hormon (ACTH) uygulamaları ile baş edebilme yetenekleri belirlenmiştir. Materyal ve Metot: 600 adet günlük yaşta civciv kontrol (C), çevresel zenginleştirme (EE), ve çevresel zenginleştirme+ısı stresi (EE+HS) olmak üzere rastgele 3 deneme grubuna ayrılmıştır. EE+HS grubundaki civcivler denemenin 21. gününde 3 saat süre ile 38±1 ºC ısı stresine maruz bırakılmışlardır. Denemenin 42. gününde C ve EE grupları Kontrol, Kontrol+ACTH, EE ve EE+ACTH olmak üzere 2 alt gruba bölünmüşlerdir. Kontrol+ACTH ve EE+ACTH gruplarındaki piliçlere kas içi 50 IU ACTH/kg enjekte edilirken, C, EE ve EE+HS grupları ısı stresine maruz bırakılmış ve oksidatif strese karşı tepkileri değerlendirilmiştir. Bulgular: Çevresel zenginleştirme etlik piliçlerin 21. gün kan kortikosteron (CORT), malondialdehid (MDA) ve karaciğer süperoksit dismutas (SOD) düzeylerini etkilememiştir. EE grubu piliçlerde ACTH enjeksiyonu CORT ve MDA konsantrasyonlarında kontrol grubu ile karşılaştırıldığında önemli düzeyde azalmaya neden olmuştur. Piliçlerin ısı stresine maruz bırakılmaları (42. gün) EE ve EE+HS gruplarına kıyasla kontrol grubunda CORT ve MDA düzeylerini önemli ölçüde arttırmış, karaciğer SOD düzeyini düşürmüştür. Gruplar arasında serum SOD seviyeleri bakımından önemli bir farklılık saptanmamıştır. ACTH uygulaması, ısı stresinden daha fazla stres reaksiyonuna sebep olmuştur. Sonuç: Bu çalışmada elde edilen sonuçlar göstermektedir ki broylerlerin ısı stresine maruz bırakılmaları veya deneysel adenokortikotropik hormon uygulaması oksidatif metabolizmada önemli tepkilere neden olmaktadır. Sonuç olarak, erken yaşlardan itibaren zenginleştirilmiş çevrede büyütme strese adaptasyon sağlanması amacıyla yararlanılabilecek bir yöntem olarak önerilebilir.

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Cite This Article

TUĞALAY, Ç. Ş., BAYRAKTAR, Ö. H., GENÇ, N. (2021). Effects of ACTH and Acute Heat Stress on Oxidative Stress in an Early Environmentally Enriched Broilers. Hayvansal Üretim, Cilt: 62 - Sayı: 2, 93–98. https://ajindex.com/articles/387941

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