The photochemical dimerization of 3 known methoxy derivatives of chalcones, (2E)-1-(2-methoxy)phenyl-3-phenylpropen-1-one (1), (2E)-1-(3-methoxy)phenyl-3-phenyl-propen-1-one (2), and (2E)-1-(4-methoxy) phenyl-3-phenylpropen-1-one (3), yielded 3 new d -truxinic type dimers in solution: rel-(1b ,2a)- di-(2-methoxy)-benzoyl-rel-(3b ,4a )-diphenylcyclobutane (4), rel-(1b ,2a )-di-(3-methoxy)benzoyl-rel-(3b, 4a )-diphenylcyclobutane (5), and rel-(1b ,2a)- di-(4-methoxy)benzoyl-rel-(3b ,4a )-diphenylcyclobutane (6), stereoselectively. Precursor chalcones showed high superoxide radical scavenging activity although the dimers were inactive.
Özet
The photochemical dimerization of 3 known methoxy derivatives of chalcones, (2E)-1-(2-methoxy)phenyl-3-phenylpropen-1-one (1), (2E)-1-(3-methoxy)phenyl-3-phenyl-propen-1-one (2), and (2E)-1-(4-methoxy) phenyl-3-phenylpropen-1-one (3), yielded 3 new d -truxinic type dimers in solution: rel-(1b ,2a)- di-(2-methoxy)-benzoyl-rel-(3b ,4a )-diphenylcyclobutane (4), rel-(1b ,2a )-di-(3-methoxy)benzoyl-rel-(3b, 4a )-diphenylcyclobutane (5), and rel-(1b ,2a)- di-(4-methoxy)benzoyl-rel-(3b ,4a )-diphenylcyclobutane (6), stereoselectively. Precursor chalcones showed high superoxide radical scavenging activity although the dimers were inactive.
YAYLI, N., ÜÇÜNCÜ, O., YAŞAR, A., GÖK, Y. (2004). Stereoselective Photochemistry of Methoxy Chalcones in Solution and Their Radical Scavenging Activity. Turkish Journal of Chemistry, Cilt: 28 - Sayı: 4, 515–521. https://ajindex.com/articles/382237