Journals / Turkish Journal of Urology / 2019 / Cilt: 45 - Sayı: 1

Evaluation of early and late-term infections after renal transplantation: Clinical experiences of Sanko University Medical Faculty Transplantation Center

Pages
63–69
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Infection more often seen in renal transplantations from cadavers.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Infections play an important part in post-transplantation causes of morbidity and mortality.
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Key Findings & Data:Thepurpose of this study is to evaluate short-, and long-term infections encountered in after renal transplantations.Material and methods: Two hundred and thirteen cases that consisted of both living and cadaver donors,who suffered from late period renal insufficiency and had renal transplant between June 2011 and January2016 at the Transplantation Center of Sanko University School of Medicine were included in the study.
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Conclusion & Impact:Infection more often seen in renal transplantations from cadavers.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Özet

Objective: Infections play an important part in post-transplantation causes of morbidity and mortality. Thepurpose of this study is to evaluate short-, and long-term infections encountered in after renal transplantations.Material and methods: Two hundred and thirteen cases that consisted of both living and cadaver donors,who suffered from late period renal insufficiency and had renal transplant between June 2011 and January2016 at the Transplantation Center of Sanko University School of Medicine were included in the study. Inthis study the short-, and long-term infections seen in post renal transplantation were examined retrospectively. Infection types, frequency and periods of infection, infection agents and predisposing factors weredetermined as the examination parameters.Results: Of the 213 patients who received renal transplant, 139 were males (65.3%) and 74 were women(34.75%) and the mean age was 42±11,8 (range, 14-70) years. Twelve (5.6%) patients exited after renal transplantation. Post-transplant infections were seen in 49 patients (23.1%) within 1-6 months; in 13 patients(6.1%) within 6-12 months; and in 5 patients (2.4%) after the 12th month. The most common infections afterrenal transplantation were associated with urinary tract (70 patients, 34.3%). The most frequently isolatedagents were E. coli (n=66; 30.9%), Kebsiella spp. (n=18; 8.4%) and Enterococci (n=18; 8.4%) respectively.The renal transplants from the cadavers were observed to contract infections 1.78 times more frequentlycompared to the living donors (OR=1.78, 95% CI=1.03-3.09).Conclusion: The most common complication after renal transplantation are infections. The majority of theinfections are seen within the first year especially between 1-6 months. Post-transplant infections are oftenrelated to urinary system. E.coli is the most frequently isolated agent and it may be responsible for urosepsisin renal transplant patients. Infection more often seen in renal transplantations from cadavers.

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Cite This Article

KAZIMOĞLU, H., HARMAN, R., MERCİMEK, M. N., DOKUR, M., UYSAL, E. (2019). Evaluation of early and late-term infections after renal transplantation: Clinical experiences of Sanko University Medical Faculty Transplantation Center. Turkish Journal of Urology, Cilt: 45 - Sayı: 1, 63–69. https://ajindex.com/articles/379554

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References (4)

  1. Alangaden GJ, Thyagarajan R, Gruber SA, Morawski K, Garnick J, El-Amm JM, et al. Infectious complications after kidney transplantation: current epidemiology and associated risk factors. Clin Transplant 2006;20:401-9. [CrossRef] Yabanoglu H, Alışkan HE, Çalışkan K, Arer I, Akdur A, Yıldırım S, et al. Early Infections in Renal Transplant Recipients: Incidence, Risk Factors, and Causative Microorganisms. Exp Clin Transplant 2015;13(Suppl 3):11-4.
  2. Adamska Z, Karczewski M, Cichańska L, Więckowska B, Małkiewicz T, Mahadea D, et al. Bacterial Infections in Renal Transplant Recipients. Transplant Proc 2015;47:1808-12. [CrossRef] Jonas M, Jóźwik A, Kawecki D, Durlik M, Pączek L, Młynarczyk G, et al. Influence of Double-J Catheters on Urinary Infections After Kidney Transplantation Transplant Proc 2016;48:1630-2.
  3. Illesy L, Szabo-Pap M, Toth F, Zadori G, Zsom L, Asztalos L, et al. Bacterial Infections After Kidney Transplantation: A SingleCenter Experience. Transplant Proc 2016;48:2540-3. [CrossRef] Guimarães LF, Halpern M, de Lemos AS, de Gouvêa EF, Gonçalves RT, da Rosa Santos MA, et al. Invasive Fungal Disease in Renal Transplant Recipients at a Brazilian Center: Local Epidemiology Matters. Transplant Proc 2016;48:2306-9. [CrossRef] Marques S, Carmo R, Ferreira I, Bustorff M, Sampaio S, Pestana M. Cryptococcosis in Renal Transplant Recipients: A Single-Center Experience. Transplant Proc 2016;48:2289-93. [CrossRef] Kirchner VA, Pruett TL. Receiving the Unwanted Gift: Infection Transmission through Organ Transplantation. Surg Infect (Larchmt) 2016;17:318-22. [CrossRef] Song Y, Zhang L, Yang H, Liu G, Huang H, Wu J, et al. Nontuberculous mycobacterium infection in renal transplant recipients: a systematic review. Infect Dis (Lond) 2018:1-8.
  4. Felipe CR, Ferreira AN, Bessa A, Abait T, Ruppel P, Paula MI, et al. The current burden of cytomegalovirus infection in kidney transplant recipients receiving no pharmacological prophylaxis. J Bras Nefrol 2017;39:413-23. [CrossRef] De Gracia-Guindo MDC, Ruiz-Fuentes MDC, Galindo-Sacristán P, Osorio-Moratalla JM, Ruiz-Fuentes N, Rodriguez Granger J, et al. Cytomegalovirus Infection Monitoring Based on Interferon Gamma Release Assay in Kidney Transplantation. Transplant Proc 2018;50:578-80. [CrossRef] Tedesco-Silva H, Felipe C, Ferreira A, Cristelli M, Oliveira N, Sandes-Freitas T, et al. Reduced Incidence of Cytomegalovirus Infection in Kidney Transplant Recipients Receiving Everolimus and Reduced Tacrolimus Doses. Am J Transplant