Journals / Turkish Journal of Obstetrics and Gynecology / 2016 / Cilt: 13 - Sayı: 2

Preeklampsi semptomları fetal ölüm sonrası kaybolur mu?

Do preeclampsia symptoms resolve after intrauterine death of a fetus?

Pages
103–105
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We think that both cases are evidence of late on-set systemic maternal effects (such as systemic maternal endothelial activation and/or systemic maternal inflammatory response) depends on preeclampsia.

📌 3 Key Takeaways

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Objective & Hypothesis:We present two cases of twin pregnancies without resolution of preeclamptic symptoms after intrauterine death of one twin.
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Key Findings & Data:Case 1: A nulliparous woman aged 37 years was referred at 26 weeks of gestation because of arterial hypertension, edema, and growth restriction in one twin.
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Conclusion & Impact:We think that both cases are evidence of late on-set systemic maternal effects (such as systemic maternal endothelial activation and/or systemic maternal inflammatory response) depends on preeclampsia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

We present two cases of twin pregnancies without resolution of preeclamptic symptoms after intrauterine death of one twin. Case 1: A nulliparous woman aged 37 years was referred at 26 weeks of gestation because of arterial hypertension, edema, and growth restriction in one twin. Three weeks later the restricted twin died. During the following three weeks, ultrasound examinations showed a reduced growth velocity of the surviving fetus and reversed umbilical flow. At the end of the 34th week of gestation, cesarean section was performed and a healthy female infant was delivered.Case 2: A nulliparous woman aged 33 years with a 27-week twin pregnancy was referred because of arterial hypertension and discordant growth. The restricted twin died at 31 weeks of gestation. Following the death, within two weeks the growth of the co-twin started to slow down and reversed end diastolic flow presented. At the end of the 33rd week of gestation, cesarean section was performed and a healthy female infant was delivered. The interesting point of these cases was the secondary effects on the co-twins. During the time after intrauterine deaths of one twin, the surviving fetuses started to show a reduced growth velocity and reversed umbilical flow and mothers had increased blood pressure and proteinuria again. We think that both cases are evidence of late on-set systemic maternal effects (such as systemic maternal endothelial activation and/or systemic maternal inflammatory response) depends on preeclampsia.

Özet

İkiz eşinin ölümünden sonra preeklamptik semptomların devam ettiği iki olguyu sunuyoruz. Olgu 1: Otuz yedi yaşında, nullipar, 26 hafta ikiz gebelik kan basıncı yüksekliği, ödem ve bir fetüste gelişme geriliği nedeniyle kliniğimize refere edildi. Üç hafta sonra geri kalan fetüs öldü. Takip eden üç haftada, ultrason ölçümlerinde yaşayan fetüsün gelişiminde yavaşlama ve umblikal arterde ters akım saptandı. Otuz dördüncü haftanın sonunda sezaryen gerçekleştirildi ve sağlıklı kız bebek doğurtuldu. Olgu 2: Otuz üç yaşında, nullipar, 27 hafta ikiz gebelik kan basıncı yüksekliği ve bir fetüste gelişme geriliği nedeniyle kliniğimize refere edildi. Otuz birinci gebelik haftasında geri kalan fetüs öldü. Takip eden 2 haftada, ultrason ölçümlerinde yaşayan fetüsün gelişiminde yavaşlama ve umblikal arterde ters akım saptandı. Otuz üçüncü haftanın sonunda sezaryen gerçekleştirildi ve sağlıklı kız bebek doğurtuldu.Bu olgulardaki ilginç nokta yaşayan ikiz eşlerindeki ikincil etkilerdi. İkiz eşinin ölümünden sonraki periyotta yaşayan fetüste gelişmede yavaşlama, ters umblikal akım ve annede kan basıncında artış ve proteinüri görüldü. Biz bu belirtilerin preeklampsinin geç başlangıçlı sistemik etkilerinin (sistemik maternal endotelyal aktivasyon ve/veya sistemik maternak enflamatuvar yanıt gibi) bir kanıtı olduğunu düşünmekteyiz.

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Cite This Article

BALCI, S., BODUR, T., TOHMA, Y. A., OKYAY, R. E., SAATLİ, B., ALTUNYURT, S. (2016). Preeklampsi semptomları fetal ölüm sonrası kaybolur mu?. Turkish Journal of Obstetrics and Gynecology, Cilt: 13 - Sayı: 2, 103–105. https://ajindex.com/articles/376431

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