Journals / Turkish Journal of Obstetrics and Gynecology / 2015 / Cilt: 12 - Sayı: 1

Overin mitotik aktif selüler Fibromu: Olgu sunumu

Mitotically active cellular fibroma of the ovary: A case report

Pages
53–55
DOI
—
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J Turk Soc Obstet Gynecol 2015;1:53-5

📌 3 Key Takeaways

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Objective & Hypothesis:Fibromas are classified in a spectrum from fibromas to fibrosarcomas according to the number of mitosis they include.
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Key Findings & Data:Cellular fibromas with less than 4 mitotic figures under 10 high power fields (HPF) are benign. "Mitotically active cellular fibromas" that are classified between the cellular fibromas and fibrosarcomas, have >=4 mitotic figures in 10 HPF but do not have nuclear atypia.
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Conclusion & Impact:J Turk Soc Obstet Gynecol 2015;1:53-5
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Fibromas are classified in a spectrum from fibromas to fibrosarcomas according to the number of mitosis they include. Malignant fibrosarcomas which have aggressive pattern show higher mitotic activity and nuclear atypia. Cellular fibromas with less than 4 mitotic figures under 10 high power fields (HPF) are benign. "Mitotically active cellular fibromas" that are classified between the cellular fibromas and fibrosarcomas, have >=4 mitotic figures in 10 HPF but do not have nuclear atypia. A very few cases of mitotically active cellular fibromas have been reported in the literature. In this report, we present the case of mitotically active cellular fibroma in a patient who applied to our clinic with the complaint of pelvic mass. J Turk Soc Obstet Gynecol 2015;1:53-5

Özet

Fibromlar, içerdikleri mitoz sayısına göre klasik fibromdan, fibrosarkoma kadar giden bir yelpazede sıralanırlar. Yüksek mitoz ve nükleer atipi, daha agresif seyirli ve malign natürlü fibrosarkomdan sorumludur. Mitozun 10 büyük büyütmede 4'ün altında olduğu olgular, yani selüler fibromlar iyi huyludur. Fibrosarkom ve selüler fibrom arasında yer alan, 4 ve üzerinde mitoza sahip olan ama nükleer atipi barındırmayan ve literatürde "mitotik aktif selüler fibrom" olarak adlandırılan ara grup, literatürde az sayıda ve olgu sunumları şeklinde bildirilmiştir. Bu olgu sunumunda da kliniğimize pelvik kitle nedeniyle başvurmuş ve operasyon sonrası overde "mitotik aktif selüler fibrom" tanısı almış bir olgu tartışılacaktır. J Turk Soc Obstet Gynecol 2015;1:53-5

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Cite This Article

YILDIRIM, N., SAATLİ, B., AKALIN, F., ULUKUŞ, Ç., OBUZ, F., SAYGILI, U. (2015). Overin mitotik aktif selüler Fibromu: Olgu sunumu. Turkish Journal of Obstetrics and Gynecology, Cilt: 12 - Sayı: 1, 53–55. https://ajindex.com/articles/376349

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