Journals / Turkish Journal of Obstetrics and Gynecology / 2017 / Cilt: 14 - Sayı: 2

Features of ovarian Brenner tumors: Experience of a single tertiary center

Ovaryan Brenner tümörlerinin özellikleri: Üçüncü basamak merkez tecrübesi

Pages
133–137
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further studies are needed to completely understand the clinical features of Brenner tumors.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Brenner tumors are rare neoplasms of the ovary.
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Key Findings & Data:Materials and Methods: The clinical features of 22 patients who were treated in Ankara University Faculty of Medicine Obstetrics and Gynecology Department between 2005 and 2015 were evaluated retrospectively from hospital medical records.Results: The patients were aged 34 to 79 years at the time of diagnosis and the mean age was 55.1 years.
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Conclusion & Impact:Further studies are needed to completely understand the clinical features of Brenner tumors.
🔬Design:Research Article
📍Scope:2005 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Brenner tumors are rare neoplasms of the ovary. The aim of this study was to investigate the clinical features of Brenner tumors. Materials and Methods: The clinical features of 22 patients who were treated in Ankara University Faculty of Medicine Obstetrics and Gynecology Department between 2005 and 2015 were evaluated retrospectively from hospital medical records.Results: The patients were aged 34 to 79 years at the time of diagnosis and the mean age was 55.1 years. Two (9.1%) patients were pre-menopausal, five (22.7%) were peri-menopausal, and 25 (68.2%) patients were postmenopausal. One patient was pregnant. Twenty of the neoplasms were benign, one was malignant, and one was both malignant and benign. There was no recurrence in the malignant cases. Six (27.2%) patients had mixed tumors consisting of Brenner tumor and another ovarian pathology. Specifically, the other component of these tumors was mucinous cystadenoma in four patients, endometriosis externa in one patient, and high-grade serous papillary cyst adenocarcinoma in one patient.Conclusion: Brenner tumors are usually incidental benign pathologic findings of surgical procedures in postmenopausal women. They can be found with other ovarian pathologies such as mucinous ovarian tumors and can coexist with other female genital tumors. Further studies are needed to completely understand the clinical features of Brenner tumors.

Özet

Amaç: Brenner tümörleri overin nadir neoplazmlarındandır. Bu çalışmanın amacı Brenner tümörlerinin klinik özelliklerinin incelenmesidir.Gereç ve Yöntemler: Ankara Üniversitesi Tıp Fakültesi Obstetrik ve Jinekoloji Anabilim Dalı'nda tedavi alan 2005-2015 yılları arasındaki 22 hasta retrospektif olarak incelenmiştir. Bulgular: Hastaların tanı aldıklarında ortalama yaşı 55,1 olmakla beraber yaş aralığı 34 ile 79 arasındaydı. İki hasta (%9,1) pre-menapozal dönemdeyken, beş hasta (%22,7) peri-menapozal dönemde ve on beş hasta (%68,2) postmenapozal dönemdeydi. Hastaların bir tanesi tanı sırasında gebeydi. Yirmi hastanın final patolojisi benign Brenner neoplazmı iken, bir tanesi malign ve bir tanesi hem benign hem malign olarak raporlanmıştır. Malign hastalarda takip süresince rekürrens görülmedi. Altı hastada (%27,2) Brenner tümörüyle beraber seyreden başka bir ovaryan patoloji vardı. Bu hastaların dördünde eşlik eden patoloji müsinöz kistadenoma iken bir hastada endometriyozis eksterna ve bir hastada yüksek gradeli seröz papiller kist adenokarsinom izlendi.Sonuç: Brenner tümörleri, genellikle postmenapozal dönemdeki kadınlarda cerrahi prosedürler sonrası rastlantısal olarak bulunan benign patolojik bulgulardır. Özellikle müsinöz over tümörü gibi başka bir ovaryan patolojiye eşlik edebilirler. Diğer kadın genital tümörleri ile beraber görülebilirler. Brenner tümörlerinin klinik özelliklerinin tam olarak anlaşılabilmesi için ek çalışmalara ihtiyaç vardır.

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Cite This Article

TURGAY, B., KOYUNCU, K., TAŞKIN, S., ORTAÇ, U. F. (2017). Features of ovarian Brenner tumors: Experience of a single tertiary center. Turkish Journal of Obstetrics and Gynecology, Cilt: 14 - Sayı: 2, 133–137. https://ajindex.com/articles/376289

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