Journals / Turkish Journal of Rheumatology(.)Archives of Rheumatology / 2009 / Cilt: 24 - Sayı: 2

Complex regional pain syndrome type 1 in both lower extremities, resistant to treatment: A case report

Bilateral ayak tutulumu gösteren tedaviye dirençli kompleks bölgesel ağrı sendromu tip 1: Bir olgu sunumu

Pages
103–105
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We suggest bilateral CRPS-1 may occur in the lower extremity and pregabalin may be an effective and alternative therapy in these patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Complex regional pain syndrome type 1 (CRPS-1) is characterized by pain, vasomotor and sudomotor changes and trophic disturbances.
📊
Key Findings & Data:Although the pathogenesis of CRPS-1 is not exactly clear, abnormal sympathetic nerve activity may be a potential etiological factor.
💡
Conclusion & Impact:We suggest bilateral CRPS-1 may occur in the lower extremity and pregabalin may be an effective and alternative therapy in these patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hastalık direnci · Ağrı · Kompleks bölgesel ağrı sendromları

Abstract

Complex regional pain syndrome type 1 (CRPS-1) is characterized by pain, vasomotor and sudomotor changes and trophic disturbances. It may develop as a result of trauma, especially extremity fractures and surgery. Although the pathogenesis of CRPS-1 is not exactly clear, abnormal sympathetic nerve activity may be a potential etiological factor. Occurrence of CRPS-1 in the lower extremity with bilateral involvement is a very rare condition. Calcitonin, bisphosphonates and analgesics can be used in the management of these cases. A case of bilateral lower extremity CRPS-1 with rebellious pain is described and discussed in this paper. We suggest bilateral CRPS-1 may occur in the lower extremity and pregabalin may be an effective and alternative therapy in these patients.

Özet

Kompleks bölgesel ağrı sendromu tip 1 ağrı, vasomotor ve sudomotor değişiklikler ve trofik bozukluklarla karakterize bir sendromdur. Travma ve cerrahi sonrası, sıklıkla da ekstremite kırıklarından sonra ortaya çıkar. Patojenezi halen tam olarak açıklanamamış olmakla birlikte sempatik sinir sisteminin anormal aktivitesine bağlı olduğu düşünülmektedir. Alt ekstremitede bilateral tutulum oldukça nadir bir durumdur. Bu olguların tedavisinde ağrının azaltılması ve fonksiyonların yeniden kazandırılması amacıyla analjezikler, kalsitonin, bifosfonatlar ve fizik tedavi ajanlarından faydalanılabilmektedir. Bu yazıda, bilateral ayak tutulumu gösteren ve analjeziklere dirençli, şiddetli ağrı ile seyreden bir kompleks bölgesel ağrı sendromu tip 1 olgusu anlatıldı ve tartışıldı. Klinik bulguların, birden fazla ekstremitede görülmesi durumunda da kompleks bölgesel ağrı sendromu tip 1 akla gelmelidir, ve analjeziklere yanıt alınamadığı zaman pregabalin etkili bir tedavi seçeneği olabilir.

🔖

Cite This Article

ALTINDAĞ, Ö., AYDENİZ, A., GÜRSOY, S., BUKAN, T. H. (2009). Complex regional pain syndrome type 1 in both lower extremities, resistant to treatment: A case report. Turkish Journal of Rheumatology(.)Archives of Rheumatology, Cilt: 24 - Sayı: 2, 103–105. https://ajindex.com/articles/376115

References (12)

  1. Ofluoğlu D, Akyüz G, Kayhan Ö, Dede F, Turoğlu HT, Erdinc TY. Posttravmatik Refleks Sempatik Distrofi Sendromunda Kalsitonin Tedavisi. Romatizma Dergisi 2003; 18:008-011
  2. Kozin F, Soin JS, Ryan LM, Carrera GF, Wortmann RL. Bone scintigraphy in the reflex sympathetic dystrophy syndrome. Radiology. 1981; 138: 437-43
  3. Tan AK, Özdem T, Dinçer K, Kalyon TA. Refleks Sempatik Distrofi Sendromu Tedavisinde Transkutanöz Elektronörostimülasyon ve Ultrasonun Etkileri. Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi 2005; 51: 83-9
  4. Livingstone WK. Pain mechanisms. A physiologic Interpretation of Causalgia and Its Related States. New York: Plenum Press, 1976
  5. Veldman PH, Goris RJ. Multiple reflex sympathetic dystrophy. Which patients are at risk for developing a recurrence of reflex sympathetic dystrophy in the same or another limb. Pain 1996; 64: 463-6
  6. Veldman PH, Jacobs PB. Reflex sympathetic dystrophy of the head: case report and discussion of diagnostic criteria. J Trauma 1994; 36: 119-21
  7. Sandroni P, Benrud-Larson LM, McClelland RL, Low PA. Complex regional pain syndrome type I: incidence and prevalence in Olmsted county, a population-based study. Pain 2003; 103: 199-207
  8. Kurvers HA, Jacobs MJ, Beuk RJ, van den Wildenberg FA, Kitslaar PJ, Slaaf DW, et al. The influence of local skin heating and reactive hyperaemia on skin blood flow abnormalities in patients with reflex sympathetic dystrophy (RSD). Eur J Clin Invest 1995; 25: 346-52
  9. Ender Berker. Nöropatik Ağrı ve Fizyopatolojik Mekanizmalar- Eğitim Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi 2005; 51 (Ek-A): 1-5
  10. Pertoldi S, Di Benedetto P. Shoulder-hand syndrome after stroke. A complex regional pain syndrome. Eura Medicophys 2005; 41: 283-92
  11. Blommel ML, Blommel AL. Pregabalin: an antiepileptic agent useful for neuropathic pain. Am J Health Syst Pharm 2007; 64: 1475-82
  12. Tan AK, Duman I, Taşkaynatan MA, Hazneci B, Kalyon TA. The effect of gabapentin in earlier stage of reflex sympathetic dystrophy. Clin Rheumatol 2007; 26: 561-5.