Behçet Hastalığında Akım Aracılı Dilatasyonun Değerlendirilmesi

Conclusion: Flow-mediated dilatation under Doppler US is simple and effective non-invasive method for predicting the early development of atherosclerosis in patients with BD

📌 3 Key Takeaways

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Objective & Hypothesis:This study aims to evaluate the early development of atherosclerosis in patients with Behçet's disease (BD) using flow-mediated dilatation (FMD) method under Doppler ultrasonography (US).

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Key Findings & Data:Patients and methods: Thirty patients with BD and 25 healthy volunteers were included.

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Conclusion & Impact:Conclusion: Flow-mediated dilatation under Doppler US is simple and effective non-invasive method for predicting the early development of atherosclerosis in patients with BD

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

This study aims to evaluate the early development of atherosclerosis in patients with Behçet's disease (BD) using flow-mediated dilatation (FMD) method under Doppler ultrasonography (US). Patients and methods: Thirty patients with BD and 25 healthy volunteers were included. Doppler US was used to measure the basal and post-reactive hyperemic diameters, peak systolic velocities, resistivity indices, and blood flow volumes of the brachial arteries. Flow- mediated dilatation was defined as the percentage of difference between the post-reactive hyperemic and basal diameters. Results: The mean FMD value of the BD group (10.8±12.7%) was significantly lower compared to the control group (26±18.6%). No statistically significant difference in other parameters was found between the groups. Conclusion: Flow-mediated dilatation under Doppler US is simple and effective non-invasive method for predicting the early development of atherosclerosis in patients with BD

Özet

Bu çalışmada Behçet hastasında erken ateroskleroz gelişimi, Doppler ultrasonografisi (US) eşliğinde girişimsel olmayan akım aracılı dilatasyon (FMD) yöntemi ile değerlendirildi.Hastalar ve yöntemler: Otuz Behçet hastası ve 25 sağlıklı gönüllü çalışmaya dahil edildi. Brakiyal arterde bazal ve reaktif hiperemi sonrası arter çapları, akım hızları, rezistivite indeksleri ve akım miktarlarını göstermek amacıyla Doppler US kullanıldı. Akım aracılı dilatasyon, bazal ve reaktif hiperemi sonrası ölçülen brakiyal arter çapları farkının yüzdesi olarak tanımlandı.Bulgular: Behçet hastalığı grubunda ortalama FMD değeri (%10.8±12.7) kontrol grubundan (%26±18.6), anlamlı derecede düşük bulundu. Diğer parametreler açısından gruplar arasında istatistiksel anlamlı farklılık bulunamadı.Sonuç: Behçet hastalarında erken ateroskleroz gelişimini göstermek amacıyla Doppler US eşliğinde FMD değerlendirilmesi basit ve girişimsel olmayan etkili bir yöntemdir

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Cite This Article

YÜKSEKKAYA, R., ÇELİKYAY, F., KOÇ, F., DENİZ, Ç., GÖKÇE, E., FIRAT, M. M., YÜKSEK, J. (2012). Behçet Hastalığında Akım Aracılı Dilatasyonun Değerlendirilmesi. Turkish Journal of Rheumatology(.)Archives of Rheumatology, Cilt: 27 - Sayı: 3, 152–157. https://ajindex.com/articles/375979

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