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Journals / Turkish Journal of Clinics and Laboratory / 2021 / Cilt: 12 - Sayı: 4

The relationship between infarct-related arteries patency with c-reactive protein/albumin ratio before primary percutaneous coronary intervention in patients with st-segment elevation myocardial infarction

St elevasyonlu miyokard enfarktüslü hastalarda enfarktüsle ilişkili arter açıklığı ile primer perkütan koroner girişim öncesi c-reaktif protein/ albümin oranı arasındaki ilişki

Halil AKIN
Önder BİLGE
Bernas ALTINTAŞ
Rojhat ALTINDAĞ
Hüseyin EDE
Mehmet Şahin ADIYAMAN
Pages
365–371
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CAR level was statistically significantly higher in TIMI flow 0-1 group when compared to TIMI flow 2-3 group [0.31 (0.09-0.51) vs 0.23 (0.06-0.42); p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Inflammatory markers such as C-reactive protein and Albumin have previously been associated with poor prognosis in ST-elevation myocardial infarction (STEMI).
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Key Findings & Data:Material and Methods: A total of 822 patients who underwent p-PCI for acute STEMI were included in this study.
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Conclusion & Impact:CAR level was statistically significantly higher in TIMI flow 0-1 group when compared to TIMI flow 2-3 group [0.31 (0.09-0.51) vs 0.23 (0.06-0.42); p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:C-reaktif protein/albümin oranı · İnfaktüsten sorumlu koroner arter açıklığı · ST elevasyonlu miyokard infarktüsü

Abstract

Aim: Inflammatory markers such as C-reactive protein and Albumin have previously been associated with poor prognosis in ST-elevation myocardial infarction (STEMI). The present study aims to investigate the relationship between the infarct-related arteries (IRA) patency and C-reactive protein/Albumin ratio (CAR) before primary percutaneous coronary intervention (p-PCI) in patients with STEMI. Material and Methods: A total of 822 patients who underwent p-PCI for acute STEMI were included in this study. Patients were divided into two groups according to IRA patency as TIMI flow 0-1 (n = 551) and TIMI flow 2-3 (n = 271). CAR ratio measured at admission was compared with IRA patency. Results: The average age of 822 patients was 55±12, and 84.3% (693) of the patients were male. The mean CAR level of the patients was determined as 0.26 (0.08-0.48). CAR level was statistically significantly higher in TIMI flow 0-1 group when compared to TIMI flow 2-3 group [0.31 (0.09-0.51) vs 0.23 (0.06-0.42); p

Özet

Amaç: C-reaktif protein ve Albumin gibi inflamatuar markerlar STEM’de daha önce kötü prognoz ile ilşkilendirilmiştir. Çalışmamızda ST elevasyonlu miyokard enfarktüsü (STEMI) geçiren hastalarda pirmer Perkütan Girişim (p-PKG) öncesi enfarktüsten sorumlu koroner arter açıklığı ile C-reaktif protein/Albumin oranı (CAR) arasındaki ilişkiyi araştırmayı amaçladık. Gereç ve Yöntem: STEMI nedeni ile p-PKG uygulanmış 822 hasta çalışmaya dahil edildi. Hastalar IRA açıklığına göre TIMI akım 0-1 (n=551) ve TIMI akım 2-3 (n=271) olarak iki gruba ayrıldı. Başvuru sırasında ölçülen CAR oranı, IRA açıklığı ile karşılaştırıldı. Bulgular: 822 hastanın yaş ortalaması 55±12’ di ve %84,3 (693)’ ü erkekti. Tüm çalışma hastalarının ortalama CAR düzeyi 0.26 (0.08-0.48) olarak tespit edildi. CAR düzeyi TIMI akım 0-1 grubunda TIMI akım 2-3 grubuna göre istatiksel anlamlılıkla daha yüksek bulundu [0.31 (0.09-0.51) vs 0.23 (0.06-0.42); p

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Cite This Article

AKIN, H., BİLGE, Ö., ALTINTAŞ, B., ALTINDAĞ, R., EDE, H., ADIYAMAN, M. Ş. (2021). The relationship between infarct-related arteries patency with c-reactive protein/albumin ratio before primary percutaneous coronary intervention in patients with st-segment elevation myocardial infarction. Turkish Journal of Clinics and Laboratory, Cilt: 12 - Sayı: 4, 365–371. https://ajindex.com/articles/373966

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