Journals / Balıkesir Medical Journal / 2019 / Cilt: 3 - Sayı: 2

Hit Two Birds With One Stone Via Thrombolytic Treatment

Trombolitik Tedavi ile Bir Taşla İki Kuş

Pages
85–89
Publication Date
2019-06-30
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

By thrombolytic therapy cardiac thrombus was dissolved and after 7 days the patient had complete neurologic recovery.

📌 3 Key Takeaways

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Objective & Hypothesis:Early data showed that in the setting of acute myocardial infarction (AMI), left ventricular thrombus (LVT) was present in most frequently in acute apical or anterior AMI.
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Key Findings & Data:Solheim et al. reported LVT incidence of 15% in the first 3 months in AMI patients who were treated with primary PCI.
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Conclusion & Impact:By thrombolytic therapy cardiac thrombus was dissolved and after 7 days the patient had complete neurologic recovery.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:sol ventrikül trombüs · apikal anevrizma · myokard infarktüsü komplikasyonları

Abstract

Early data showed that in the setting of acute myocardial infarction (AMI), left ventricular thrombus (LVT) was present in most frequently in acute apical or anterior AMI. There are several studies on the frequency of LVT formation in patients treated with precurtain coronary intervention (PCI). Solheim et al. reported LVT incidence of 15% in the first 3 months in AMI patients who were treated with primary PCI. In a meta-analysis it was shown that LVT is an important problem especially among patients with anterior AMI and management strategy is a point of interest. The incidence of LVT is in a decline recently. According to the current guidelines, immediate revascularisation of infarct related artery, use of sufficient anticoagulant therapy and agents that improve remodelling of the left ventricle was associated with decrease in incidence of LVT. Although the use of ACE-inhibitors had a favourable effect on left ventricle remodelling, there were no differences in LVT formation between those patients on ACE-inhibitor therapy and those who were not. LVT formation is associated with the infarct region, more frequent in anterior AMI, extent of infarct area and presence of aneurysm. In this case report we present a patient applied to the hospital with neurologic symptoms and diagnosed with acute ischemic stroke possibly due to left ventricle thrombus, possibly developed after the anterior MI 20 days ago. By thrombolytic therapy cardiac thrombus was dissolved and after 7 days the patient had complete neurologic recovery.

Özet

Son çalışmalar, sol ventrikül trombüsü (LVT) en sık akut anterior miyokard infarktüsü (AMI) sonrasında görülmektedir. AMI sonrası perkütan koroner girişim (PCI) uygulanan hastalarda LVT oluşumu sıklığına dair çeşitli çalışmalar mevcuttur Solheim ve ark. anterior AMI sonrası ilk 3 ay içinde LVT oluşum insidansını %15 olarak bildirmişlerdir. Yine bir meta-analizde LVT'nin özellikle anterior AMI'de görülen önemli bir komplikasyon olup, tedavi yönetimi konusu ilgi çekmektedir. Son zamanlarda klavuzların tavsiyesi doğrultusunda AMI ile gelen vakaların hızlı revaskülarizasyonu sonrasında sol ventrikül yeniden şekillenmesine etkili ilaçların, antikoagulan ve antiagregan kulanımının yaygınlaşması ile LVT görülme sıklığı giderek azalmakla birlikte, ACE kullanmakta olan grup ile kullanmayan grup arasında LVT oluşumu açısından fark bulunamamıştır. LVT oluşumu infarkt bölgesi, yaygınlığı ve anevrizma olup olmadığı ile ilişkili bulunmuştur. Bu olgu bildirisinde hastaneye nörolojik şikayetlerle başvuran sonrasında akut iskemik strok tanısı almış, 20 gün öncesinde akut anterior AMI öyküsü olan ekokardiyografisinde sol ventrikül trombüsü saptanmış bir vaka anlatılmaktadır. Hastaya trombolitik tedavi uygulanmış olup tedaviden 7 gün sonrasında nörolojik fonksiyonlarının normale dönmesinin yanısıra LVT tamamen gerilemiştir.

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Cite This Article

ÖZKALAYCI, F., HAKGÖR, A., KARAKOYUN, S., KARAGÖZ, A., Tanboğa, İ. H. (2019). Hit Two Birds With One Stone Via Thrombolytic Treatment. Balıkesir Medical Journal, Cilt: 3 - Sayı: 2, 85–89. https://ajindex.com/articles/373670

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References (1)

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