Journals / İstanbul Tıp Fakültesi Dergisi / 2021 / Cilt: 84 - Sayı: 3

WHAT’S NEW IN METASTATIC COLON CANCER TREATMENT?

METASTATİK KOLON KANSERİ TEDAVİSİNDEKİ YENİLİKLER

Pages
425–429
Publication Date
2021-07-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Molecular evaluations have become extremely important in terms of prognosis and predictions in the treatment of mCRC, as in many tumors today.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this review, we present the current innovations in the field of metastatic colon cancer (mCRC).
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Key Findings & Data:Immunotherapy is the treatment option in patients with 5-6% and dMMR/MSI.
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Conclusion & Impact:Molecular evaluations have become extremely important in terms of prognosis and predictions in the treatment of mCRC, as in many tumors today.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Metastatik kolon kanser · tedavi · yenilikler

Abstract

In this review, we present the current innovations in the field of metastatic colon cancer (mCRC). Tumor placement is important in the mCRC treatment decision, and KRAS, NRAS, BRAF mutation analysis is performed in terms of prognosis/predictivity. Immunotherapy is the treatment option in patients with 5-6% and dMMR/MSI. The concept of NeoRAS will become more on the agenda in the near future as high-level evidence becomes available. Molecular evaluations have become extremely important in terms of prognosis and predictions in the treatment of mCRC, as in many tumors today.

Özet

Bu derlemede metastatik kolon kanseri (mKRK)’ndeki medikal alandaki güncel yenilikler değerlendirildi. mKRK tedavi kararında tümör yerleşimi önemlidir ve KRAS, NRAS, BRAF mutasyon analizi prognoz/prediktivite açısından yapılmaktadır. İmmünoterapi %5-6 ve dMMR/MSI olan hasta grubunda tedavi seçeneğidir. NeoRAS kavramı, kanıt düzeyi yüksek bilgiler artıkça yakın gelecekte daha fazla gündemde olacaktır. Günümüzdeki birçok tümör tedavisinde olduğu gibi mKRK tedavisinde de moleküler değerlendirmeler prognoz ve prediktif açıdan son derece önemli hale gelmiştir.

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Cite This Article

KARABULUT, S., KARABULUT, M., TAŞTEKİN, D. (2021). WHAT’S NEW IN METASTATIC COLON CANCER TREATMENT?. İstanbul Tıp Fakültesi Dergisi, Cilt: 84 - Sayı: 3, 425–429. https://ajindex.com/articles/373280

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References (2)

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