Journals / İstanbul Tıp Fakültesi Dergisi / 2021 / Cilt: 84 - Sayı: 4

ERUPTIVE XANTHOMA: A MARKER OF HYPERTRIGLYCERIDEMIA

BİR HİPERTRİGLİSERİDEMİ BULGUSU: ERÜPTİF KSANTOM

Pages
603–606
Publication Date
2021-10-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

His body mass index was 30 kg/m2 and his laboratory results showed high serum triglyceride and glucose levels (triglyceride 6548 mg/dL, glucose 245 mg/dL), his hemoglobin A1c was 11.2%.

📌 3 Key Takeaways

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Objective & Hypothesis:Eruptive xanthomas are benign lesions which are found in extensor surfaces of the extremities and are often associated with hypertriglyceridemia and/or uncontrolled diabetes.
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Key Findings & Data:In this case report, we present a patient with hypertriglyceridemia, type 2 diabetes mellitus and eruptive xanthomas who recovers fully after treatment.
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Conclusion & Impact:His body mass index was 30 kg/m2 and his laboratory results showed high serum triglyceride and glucose levels (triglyceride 6548 mg/dL, glucose 245 mg/dL), his hemoglobin A1c was 11.2%.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Erüptif ksantom · hipertrigliseridemi · tip 2 diyabet

Abstract

Eruptive xanthomas are benign lesions which are found in extensor surfaces of the extremities and are often associated with hypertriglyceridemia and/or uncontrolled diabetes. In this case report, we present a patient with hypertriglyceridemia, type 2 diabetes mellitus and eruptive xanthomas who recovers fully after treatment. A 37-year-old male patient presented to our clinic with reddish yellow lesions on his elbows. His body mass index was 30 kg/m2 and his laboratory results showed high serum triglyceride and glucose levels (triglyceride 6548 mg/dL, glucose 245 mg/dL), his hemoglobin A1c was 11.2%. Although eruptive xanthomas have a benign nature, they are associated with disease which often need lifelong treatment.

Özet

Erüptif ksantomlar, ekstremitelerin ekstansör yüzlerinde bulunan ve sıklıkla hipertrigliseridemi ve/veya kontrolsüz diyabet ile ilişkili iyi huylu lezyonlardır. Bu olgu sunumunda hipertrigliseridemi, tip 2 diyabet ve erüptif ksantomları olan ve tedaviden sonra tamamen iyileşen bir hastayı sunuyoruz. 37 yaşında erkek hasta, dirseklerinde kırmızımsı sarı renkli lezyonlar ile kliniğimize başvurdu. Vücut kitle indeksi 30 kg/m2 ve laboratuvar sonuçlarında yüksek trigliserid ve glukoz seviyeleri (trigliserid 6548 mg/dL, glukoz 245 mg/dL) ile birlikte hemoglobin A1c % 11.2 idi. Erüptif ksantomlar iyi huylu olmalarına rağmen, genellikle ömür boyu tedavi gerektiren hastalıklarla ilişkilidirler.

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Cite This Article

ÇAKMAK, R., ÇAKLILI, Ö. T., SELÇUKBİRİCİK, Ö. S. (2021). ERUPTIVE XANTHOMA: A MARKER OF HYPERTRIGLYCERIDEMIA. İstanbul Tıp Fakültesi Dergisi, Cilt: 84 - Sayı: 4, 603–606. https://ajindex.com/articles/373260

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References (15)

  1. Hsueh YC, Chou CL, Lee TI. Diabetic dyslipidemia with eruptive xanthoma. Cleve Clin J Med 2019
  2. 86(9):575. [CrossRef] 2. Muhammad Kashif, Hanesh Kumar, Misbahuddin K. An unusual presentation of eruptive xanthoma A case report and literature review. Medicine (Baltimore) 2016
  3. 95(37):e4866. [CrossRef] 3. Zak A, Zeman M, Slaby A, Vecka M. Xanthomas: clinical and pathophysiological relations. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014
  4. 158(2):181-8. [CrossRef] 4. Kala J, Mostow EN. Eruptive xanthoma. N Engl J Med 2012
  5. 366(9):835. [CrossRef] 5. Streit E, Helmbold P. 65-year-old man with yellow-orange papules on both forearms. Eruptive xanthomas. Hautarzt 2009
  6. 60(10):834-7. [CrossRef] 6. Mangili LC, Miname MH, Silva PRS, Bittencourt MS, Rocha VZ, Mangili OC, et al. Achilles tendon xanthomas are associated withthe presence and burden of subclinical coronary atherosclerosis inheterozygous familial hypercholesterolemia: A pilot study. Atherosclerosis 2017
  7. [CrossRef] 7. Lee SY, Sheth CA. Eruptive xanthoma associated with severe hypertriglyceridemia and poorly controlled type 1 diabetes mellitus. J Community Hosp Intern Med Perspect 2019
  8. 9(4):344-6. [CrossRef] 8. Christoffersen M, Frikke-Schmidt R, Schnohr P, Jensen GB, Nordestgaard BG, Tybjærg-Hansen A. Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort study. BMJ 2011
  9. d5497. [CrossRef] 9. Duzayak S, Sayiner ZA, Erkılıç S, Inaloz HS. Acute pancreatitis with eruptive xanthoma. BMJ case reports. 2017
  10. bcr2017221543. [CrossRef] 10. Fredrickson DS. An international classification of hyperlipidemias and hyperlipoproteinemias. Ann Intern Med 1971
  11. 75(3):471-2. [CrossRef] 11. Cnop M. Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes. Biochem Soc Trans 2008
  12. 36(Pt 3):348-52. [CrossRef] 12. Shimabukuro M, Ohneda M, Lee Y. Unger, RH. Role of nitric oxide in obesity induced β-cell disease. J Clin Invest 1997
  13. 100(2):290-5. [CrossRef] 13. Alagözlü H, Cindoruk M, Karakan T. Ünal S. Heparin and insulin in the treatment of hypertriglyceridemia-induced severe acute pancreatitis. Dig Dis Sci 2006
  14. 51(5):931-3. [CrossRef] 14. Ewald N, Kloer HU. Treatment options for severe hypertriglyceridemia (SHTG): the role of apheresis. Clin Res Cardiol Suppl 2012
  15. 7(Suppl 1):31-5. [CrossRef] 15. Joseph L Witztum, D Gaudet, Steven D Freedman et al. Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome. N Engl J Med