Akdeniz benekli ateşi: 16 olgunun retrospektif incelenmesi

Conclusion: Mediterranean spotted fever should be considered in the differential diagnosis of all patients admitting with fever, maculopapular rash, headache and/or musclejoint pain during spring, summer and autumn.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Mediterranean spotted fever (MSF) is an acute febrile, zoonotic disease caused by Rickettsia conorii and endemic infectious disease in Mediterranean countries.

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Key Findings & Data:Patients and Methods: In this study, a retrospective examination of 16 cases (4 females, 12 males; mean age 38.9±13.0; range 18 to 64 years) that were diagnosed with rickettsioses between 1987-2007 was performed.

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Conclusion & Impact:Conclusion: Mediterranean spotted fever should be considered in the differential diagnosis of all patients admitting with fever, maculopapular rash, headache and/or musclejoint pain during spring, summer and autumn.

🔬Design:Research Article

📍Scope:2007 Verileri

⚙️Variables:Domain Parameters

Abstract

Objectives: Mediterranean spotted fever (MSF) is an acute febrile, zoonotic disease caused by Rickettsia conorii and endemic infectious disease in Mediterranean countries. Patients and Methods: In this study, a retrospective examination of 16 cases (4 females, 12 males; mean age 38.9±13.0; range 18 to 64 years) that were diagnosed with rickettsioses between 1987-2007 was performed. Diagnosis of MSF was based upon epidemiological and clinical features, indirect immunofluorescence antibody (IFA), as well as response to doxycycline therapy. Results: High fever and maculopapular rash were present in all cases. Palmar and plantar rash were evident in 13 (81.3%) and eschar in eight (50%) cases. All cases responded to treatment within 2±0.9 days, and no death was observed. Conclusion: Mediterranean spotted fever should be considered in the differential diagnosis of all patients admitting with fever, maculopapular rash, headache and/or musclejoint pain during spring, summer and autumn.

Özet

Amaç: Rickettsia conorii'nin neden olduğu Akdeniz benekli ateşi (ABA), Akdeniz ülkelerinde akut, endemik, zoonotik bir enfeksiyon hastalığıdır. Bu hastalık ülkemiz için endemik olduğundan sunmayı amaçladık. Hastalar ve Yöntemler: Bu çalışmada, 1987-2007 yılları arasında riketsiyoz tanısı alan 16 olgu (4 kadın, 12 erkek; ort. yaş 38.9±13.0; dağılım 18-64) retrospektif olarak incelendi. Akdeniz benekli ateşi tanısı epidemiyolojik özellikleri, indirekt floresan antikor testi (IFA), hastaların klinik bulguları ve doksisiklin tedavisine verdikleri yanıta göre kondu. Bulgular: Olguların tümünde ateş yüksekliği, makülopapüler döküntü tespit edildi. On üç (%81.3) olguda avuç içi ve ayak tabanında döküntü; sekiz olguda (%50) eskar tespit edildi. Tedaviye yanıt 2±0.9 günde gelişti ve tüm olgularda tedaviye yanıt alındı. Sonuç: İlkbahar, yaz ve sonbahar aylarında, ateş, makülopapüler döküntü, baş ağrısı ve/ veya kas-eklem ağrısı yakınmalarıyla başvuran olgularda ayırıcı tanıda mutlaka ABA düşünülmelidir.

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Cite This Article

YILMAZ, E., AKALIN, H., MISTIK, R., HEPER, Y., ENGİN, A., KILIÇASLAN, E., ÖZTÜFEKÇİ, A., SEVGİCAN, E., HELVACI, S., TÖRE, O. (2010). Akdeniz benekli ateşi: 16 olgunun retrospektif incelenmesi. Trakya Üniversitesi Tıp Fakültesi Dergisi, Cilt: 27 - Sayı: 2, 167–171. https://ajindex.com/articles/369776

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