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Journals / Turkish Journal of Cancer / 2000 / Cilt: 30 - Sayı: 2

Nasopharyngeal carcinoma case with glutathione-S-transferase-$\pi$ positivity by immunohistochemistry

Hasan ÜSTÜN
Melek ÜSTÜN
Gülten KARPUZOĞLU
Burhan SAVAŞ
Pages
86–88
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Detection of glutathione S-transferase-$\pi$ positivity by immunohistochemistry may affect therapy modalities in chemotherapy resistant cases

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This report describes a case of stage IV undifferentiated nasopharyngeal carcinoma with glutathione S-transferase-$\pi$ positivity shown in the lymph node metastasis by immunohistochemistry.
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Key Findings & Data:Chemotherapy resistance is a major problem in the treatment of patients with nasopharyngeal carcinoma and glutathione S-transferases contribute to the resistance.
💡
Conclusion & Impact:Detection of glutathione S-transferase-$\pi$ positivity by immunohistochemistry may affect therapy modalities in chemotherapy resistant cases
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:İlaç tedavisi · Glutatyon transferaz · İmmünohistokimya

Abstract

This report describes a case of stage IV undifferentiated nasopharyngeal carcinoma with glutathione S-transferase-$\pi$ positivity shown in the lymph node metastasis by immunohistochemistry. Chemotherapy resistance is a major problem in the treatment of patients with nasopharyngeal carcinoma and glutathione S-transferases contribute to the resistance. Detection of glutathione S-transferase-$\pi$ positivity by immunohistochemistry may affect therapy modalities in chemotherapy resistant cases

Özet

This report describes a case of stage IV undifferentiated nasopharyngeal carcinoma with glutathione S-transferase-$\pi$ positivity shown in the lymph node metastasis by immunohistochemistry. Chemotherapy resistance is a major problem in the treatment of patients with nasopharyngeal carcinoma and glutathione S-transferases contribute to the resistance. Detection of glutathione S-transferase-$\pi$ positivity by immunohistochemistry may affect therapy modalities in chemotherapy resistant cases

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Cite This Article

ÜSTÜN, H., ÜSTÜN, M., KARPUZOĞLU, G., SAVAŞ, B. (2000). Nasopharyngeal carcinoma case with glutathione-S-transferase-$\pi$ positivity by immunohistochemistry. Turkish Journal of Cancer, Cilt: 30 - Sayı: 2, 86–88. https://ajindex.com/articles/368434

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References (9)

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