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Journals / The Anatolian Journal of Cardiology / 2017 / Cilt: 18 - Sayı: 1

Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy

SİNEM ÖZBAY ÖZYILMAZ
Özgür AKGÜL
Hüseyin UYAREL
Hamdi PÜŞÜROĞLU
Muammer KARAYAKALI
Mehmet GÜL
Mustafa ÇETİN
Hulusi SATILMIŞOĞLU
Aydın YILDIRIM
İHSAN BAKIR
Pages
54–61
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It seems to be associated with increased ventricular arrhythmias and some echocardiographic parameters

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: It has been shown that the presence of fragmented QRS (fQRS) is associated with poor prognosis in many cardiovascular diseases and in patients with hypertrophic cardiomyopathy (HCM).
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Key Findings & Data:The aim of this study was to determine the relationship between QRS and the predicted risk score of sudden cardiac death at 5 years (HCM Risk-SCD) in HCM patients.Methods: In total, 115 consecutive HCM patients were included in this prospective observational study.
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Conclusion & Impact:It seems to be associated with increased ventricular arrhythmias and some echocardiographic parameters
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: It has been shown that the presence of fragmented QRS (fQRS) is associated with poor prognosis in many cardiovascular diseases and in patients with hypertrophic cardiomyopathy (HCM). However, no study has shown an association with the absolute risk score of sudden cardiac death. The aim of this study was to determine the relationship between QRS and the predicted risk score of sudden cardiac death at 5 years (HCM Risk-SCD) in HCM patients.Methods: In total, 115 consecutive HCM patients were included in this prospective observational study. The patients were divided into two groups according to the presence [fQRS(+) group (n=65)] or absence [fQRS(–) group (n=50)] of fQRS on a 12-lead electrocardiogram (ECG).Results: The HCM Risk-SCD (%) HCM Risk-SCD (>6%) values and some echocardiographic parameters, including ventricular extrasystole, ventricular tachycardia, cardiopulmonary resuscitation, implantable cardioverter defibrillator implantation, appropriate shock, and heart failure at the time of admission, were significantly higher in the fQRS(+) group than in the fQRS(–) group (all p 4 was identified as an effective cut-off point in fQRS for HCM. An HCM Risk-SCD value of >4 yielded a sensitivity of 77% and a specificity of 76%.Conclusion: fQRS is determined to be an independent high-risk indicator of HCM Risk-SCD. It seems to be associated with increased ventricular arrhythmias and some echocardiographic parameters

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Cite This Article

ÖZYILMAZ, S. Ö., AKGÜL, Ö., UYAREL, H., PÜŞÜROĞLU, H., KARAYAKALI, M., GÜL, M., ÇETİN, M., SATILMIŞOĞLU, H., YILDIRIM, A., BAKIR, İ. (2017). Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. The Anatolian Journal of Cardiology, Cilt: 18 - Sayı: 1, 54–61. https://ajindex.com/articles/367272

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