Journals / The Anatolian Journal of Cardiology / 2015 / Cilt: 15 - Sayı: 5

Spontan koroner arter diseksiyonu: iki kurumdan vaka serisi ve literatürün gözden geçirilmesi

Spontaneous coronary artery dissection: Case series from two institutions with literature review

Pages
409–415
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Regarding treatment, PCI seems effective with adequate long-term results

📌 3 Key Takeaways

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Objective & Hypothesis:Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome (ACS).
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Key Findings & Data:In the current literature, all case series report less than 50 patients, most of whom are either young peripartum women or women who have used oral contraceptives over long periods.
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Conclusion & Impact:Regarding treatment, PCI seems effective with adequate long-term results
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Domain Parameters

Abstract

Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome (ACS). Consequently, its presentation and optimal treatment are yet to be clearly defined. In the current literature, all case series report less than 50 patients, most of whom are either young peripartum women or women who have used oral contraceptives over long periods. All information in this study was compiled by the database service from two hospitals, the first one between 2003 and 2012 and the second one between 2007 and 2012, to include the clinical characteristics, angiography. and treatment approaches in the study population. The study population consisted in four women (50%) and four men (50%) whose ages ranged between 28 and 57 years. Two women had a history of oral contraceptive use and three women presented during peripartum. None of the patients had traditional cardiovascular risk factors or previous heart disease. In 88% of the cases, the principal diagnoses were non-ST segment elevation myocardial infarction and unstable angina. All patients underwent emergency coronary angiography and percutaneous coronary intervention. Half of them were treated with drug-eluting stents and the other half with bare metal stents. The most frequent type of dissection was NIHBL Type E, and the right coronary artery was the most frequently compromised. SCAD is a rare cause of ACS; however, its identification has improved due to the availability of angiography and new complementary techniques. Regarding treatment, PCI seems effective with adequate long-term results

Özet

Spontan koroner arter diseksiyonu (SKAD) akut koroner sendrom (AKS)'un nadir bir nedenidir. Dolayısıyla, prezentasyonu ve optimal tedavisi henüz açık olarak tanımlanmamıştır. Güncel literatürde, bütün vaka serileri, çoğu genç peripartum veya uzun zaman boyunca oral kontraseptifler kullanmış kadınlar olan 50'den az hastayı rapor etmiştir. Bu çalışmadaki bütün bilgiler; çalışma popülasyonundaki klinik karakteristikleri, anjiyografi ve tedavi yaklaşımlarını içermek üzere iki hastanenin veritabanı hizmetinden derlendi: ilki 2003 ve 2012 arası, ikincisi 2007 ve 2012 arası. Çalışma popülasyonu yaşları 28 ile 57 arasında değişen dört kadın (%50) ve 4 erkekten (%50) oluştu. İki kadının oral kontraseptif kullanım öyküsü vardı, ve üç kadın peripartum sırasında baş- vurdu. Hiçbir hastada geleneksel kardiyovasküler risk faktörleri veya önceden bir kalp hastalığı yoktu. Vakaların %88'inde, başlıca tanılar ST-segment yükselmesi olmayan miyokard infarktüsü ve anstabil anjina idi. Bütün hastalara acil koroner anjiyografi ve perkütan koroner girişim uygulandı. Yarısı ilaç kaplı stentler ile tedavi edildi ve diğer yarısı düz metal stentler ile tedavi edildi. En sık görülen diseksiyon tipi NIHBL Tip E idi ve en sık olarak sağ koroner arter risk altındaydı. SKAD AKS'nin nadir bir nedenidir bununla birlikte anjiyografinin ve yeni tamamlayıcı tekniklerin uygulanabilmesi sayesinde tanısı artmaktadır. Tedavi ile ilgili olarak, yeterli uzun dönem sonuçlarıyla birlikte PCI etkili görünmektedir.

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Cite This Article

URİBE, C. E., RAMİREZ-BARRERA, J. D., RUBİO, C., GALLEGOS, C., OCAMPO, L. A., SALDARRİAGA, C., EUSSE, C., TENORİO, C., LOPEZ, N., MORENO, A., JARAMİLLO, N. G., CHEHRAZİ-RAFFLE, A. M., SİNGH, V., MARTİNEZ-CLARK, P. (2015). Spontan koroner arter diseksiyonu: iki kurumdan vaka serisi ve literatürün gözden geçirilmesi. The Anatolian Journal of Cardiology, Cilt: 15 - Sayı: 5, 409–415. https://ajindex.com/articles/365961

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References (1)

  1. Huber MS, Mooney JF, Madison J, Mooney MR. Use of a Morphologic Classification to Predict Clinical Outcome After Dissection from Coronary Angioplasty. Am J Cardiol 1991; 68: 467-71. [CrossRef] 2. Hayes SN. Spontaneous coronary artery dissection (SCAD): new insights into this not-so-rare condition. Tex Heart Inst J 2014; 41: 295-8. [CrossRef] 3. Alfonso F, Paulo M, Gonzalo N, Dutary J, Jimenez-Quevedo P, Lennie V, et al. Diagnosis of spontaneous coronary artery dissection by optical coherence tomography. J Am Coll Cardiol 2012; 59: 1073-9. [CrossRef] 4. Tweet MS, Hayes SN, Pitta SR, Simari RD, Lerman A, Lennon RJ, et al. Clinical features, management, and prognosis of spontaneous coronary artery dissection. Circulation 2012; 126: 579-88. [CrossRef] 5. Vrints CJ. Spontaneous coronary artery dissection. Heart 2010; 96: 801-8. [CrossRef] 6. Paulo M, Sandoval J, Lennie V, Dutary J, Medina M, Gonzalo N, et al. Combined use of OCT and IVUS in spontaneous coronary artery dissection. JACC Cardiovasc Imaging 2013; 6: 830-2. [CrossRef] 7. Miki K, Fujii K, Nakata T, Shibuya M, Fukunaga M, Kawai K, et al. The utility of intravascular ultrasound for the diagnosis and management of spontaneous coronary artery dissection in a middleaged woman with acute inferior myocardial infarction. J Cardiol Cases 2012; 6: e78-e80. [CrossRef] 8. Verma PK, Sandhu MS, Mittal BR, Aggarwal N, Kumar A, Mayank M, et al. Large spontaneous coronary artery dissections: A study of three cases, literature review, and possible therapeutic strategies. Angiology 2004; 55: 309-18. [CrossRef] 9. Mortensen KH, Thuesen L, Kristensen IB, Christiansen EH. Spontaneous coronary artery dissection: a Western Denmark Heart Registry study. Catheter Cardiovasc Interv 2009; 74: 710-7. [CrossRef] 10. Vanzetto G, Berger-Coz E, Barone-Rochette G, Chavanon O, Bouvaist H, Hacini R, et al. Prevalence, therapeutic management and medium-term prognosis of spontaneous coronary artery dissection: results from a database of 11.605 patients. Eur J Cardiothorac Surg 2009; 35: 250-4. [CrossRef] 11. Rajab TK, Khalpey Z, Kraemer B, Resnic FS, Gallegos RP. Recurrent post-partum coronary artery dissection. J Cardiothorac Surg 2010; 5: 78. [CrossRef] 12. Alfonso F, Paulo M, Lennie V, Dutary J, Bernardo E, JimenezQuevedo P, et al. Spontaneous coronary artery dissection: longterm follow-up of a large series of patients prospectively managed with a "conservative" therapeutic strategy. JACC Cardiovasc Interv 2012; 5: 1062-70. [CrossR