AI Summary & Key Takeaways
AI InsightROC curve areas of A, β, and Aβ were 0.85, 0.79, and 0.83, respectively, and significant differences were observed in thesevalues among three Gensini score groups of the CAD patients.Conclusion: Varying degrees of CM function deterioration was observed in CAD patients both in ischemic and non-ischemic areas, with thedeterioration being more sever in the former.
📌 3 Key Takeaways
Özet
Objective: The aim of this study was to evaluate the value of real-time myocardial contrast echocardiography (RT-MCE) for detecting coronarymicrocirculation (CM) function in coronary artery disease (CAD) patients.Methods: Sixty-five consecutive patients were divided into CAD (n=52) and no-CAD (n=13) groups using coronary angiography (CAG). All patientsunderwent RT-MCE at rest and CAG within 1 week after RT-MCE. The ventricular segments in CAD patients were divided semi-quantitatively intoischemic and non-ischemic myocardial groups based on RT-MCE images. Myocardial blood volume (A), myocardial blood flow velocity (β), andmean myocardial blood flow (Aβ) were obtained. The Gensini scores were calculated for CAD patients. The receiver operating characteristic(ROC) curve areas of A, β, and Aβ were calculated to assess CM function in CAD patients.Results: A total of 798 and 204 segments were investigated in the CAD and non-CAD groups, respectively. In CAD patients, 332 ischemic and466 non-ischemic segments were identified. The values of A, β, and Aβ were significantly different among non-CAD, CAD, ischemic, and nonischemicgroups. ROC curve areas of A, β, and Aβ were 0.85, 0.79, and 0.83, respectively, and significant differences were observed in thesevalues among three Gensini score groups of the CAD patients.Conclusion: Varying degrees of CM function deterioration was observed in CAD patients both in ischemic and non-ischemic areas, with thedeterioration being more sever in the former.