Journals / The Anatolian Journal of Cardiology / 2019 / Cilt: 22 - Sayı: 1

Timing and magnitude of regional right ventricular function and their relationship with early hospital mortality in patients with acute pulmonary embolism

Pages
26–32
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Electromechanical delay index might be useful to predictearly hospital mortality in patients with APE. (Anatol J Cardiol 2019; 22: 26-32)

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Right ventricular (RV) dysfunction in acute pulmonary embolism (APE) has been associated with increased mortality and morbidity.The aim of the present study was to assess the timing and magnitude of regional RV functions using speckle-tracking echocardiography (STE)and their relationship to early hospital mortality in patients with APE.Methods: One hundred forty-two patients were prospectively studied at the onset of an acute episode and after a median follow-up period of30 days.
📊
Key Findings & Data:For all patients, conventional two-dimensional echocardiography and STEwere performed within 24 h after the diagnosis of APE.Results: Twenty-eight (19.7%) patients died during the hospitalization follow-up.
💡
Conclusion & Impact:Electromechanical delay index might be useful to predictearly hospital mortality in patients with APE. (Anatol J Cardiol 2019; 22: 26-32)
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Özet

Objective: Right ventricular (RV) dysfunction in acute pulmonary embolism (APE) has been associated with increased mortality and morbidity.The aim of the present study was to assess the timing and magnitude of regional RV functions using speckle-tracking echocardiography (STE)and their relationship to early hospital mortality in patients with APE.Methods: One hundred forty-two patients were prospectively studied at the onset of an acute episode and after a median follow-up period of30 days. Their clinical and laboratory characteristics were recorded. For all patients, conventional two-dimensional echocardiography and STEwere performed within 24 h after the diagnosis of APE.Results: Twenty-eight (19.7%) patients died during the hospitalization follow-up. Patients who died during hospitalization were older and hadhigher high sensitivity cardiac troponin T levels, and a higher percentage of patients had simplified Pulmonary Embolism Severity Indexes. In STEanalyses, they had lower RV free wall peak longitudinal systolic strain (PLSS) and higher RV peak systolic strain dispersion indexes. The time toPLSS difference between RV free wall and LV lateral was longer in patients who died during hospitalization than in those who survived, and thiswas an independent predictor of early hospital mortality with 85.7% sensitivity and 75.0% specificity in patients with APE.Conclusion: APE was associated with RV electromechanical delay and dispersion. Electromechanical delay index might be useful to predictearly hospital mortality in patients with APE. (Anatol J Cardiol 2019; 22: 26-32)

🔖

Cite This Article

KANAR, B. G., ŞAHİN, A., GÖL, G., OĞUR, E., KAVAS, M., ATAŞ, H., MUTLU, B. (2019). Timing and magnitude of regional right ventricular function and their relationship with early hospital mortality in patients with acute pulmonary embolism. The Anatolian Journal of Cardiology, Cilt: 22 - Sayı: 1, 26–32. https://ajindex.com/articles/365772

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Konstantinides SV, Torbicki A, Agnelli G, Danchin N, Fitzmaurice D, Galiè N, et al.; Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. Eur Heart J 2014; 35: 3033-69
  2. Mayo J, Thakur Y. Acute pulmonary embolism: from morphology to function. Semin Respir Crit Care Med 2014; 35: 41-9
  3. Becattini C, Agnelli G. Predictors of mortality from pulmonary embolism and their influence on clinical management. Thromb Haemost 2008; 100: 747-51
  4. Angriman F, Vazquez FJ, Roy PM, Le Gal G, Carrier M, Gandara E. A new prognostic strategy for adult patients with acute pulmonary embolism eligible for outpatient therapy. J Thromb Thrombolysis 2017; 43: 326-32
  5. Grifoni S, Olivotto I, Cecchini P, Pieralli F, Camaiti A, Santoro G, et al. Short-term clinical outcome of patients with acute pulmonary embolism, normal blood pressure, and echocardiographic right ventricular dysfunction. Circulation 2000; 101: 2817-22
  6. Kanar BG, Tigen MK, Sunbul M, Cincin A, Atas H, Kepez A, et al. The impact of right ventricular function assessed by 2-dimensional speckle tracking echocardiography on early mortality in patients with inferior myocardial infarction. Clin Cardiol 2018; 41: 413-8
  7. Fujikura K, Kwong D, Nguyen TT, Garcia MJ. Quick recovery of left ventricular dyssynchrony after anticoagulation in acute pulmonary embolism. Int J Cardiol 2014; 172: e167-9
  8. Rajagopalan N, Dohi K, Simon MA, Suffoletto M, Edelman K, Murali S, et al. Right ventricular dyssynchrony in heart failure: a tissue Doppler imaging study. J Card Fail 2006; 12: 263-7
  9. Meris A, Faletra F, Conca C, Klersy C, Regoli F, Klimusina J, et al. Timing and magnitude of regional right ventricular function: a speckle tracking-derived strain study of normal subjects and patients with right ventricular dysfunction. J Am Soc Echocardiogr 2010; 23: 823-31
  10. Vitarelli A, Barillà F, Capotosto L, D'Angeli I, Truscelli G, De Maio M, et al. Right ventricular function in acute pulmonary embolism: a combined assessment by three-dimensional and speckle-tracking echocardiography. J Am Soc Echocardiogr 2014; 27: 329-38
  11. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular I