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Journals / The Anatolian Journal of Cardiology / 2019 / Cilt: 22 - Sayı: 5

Association between serum adropin levels and isolated coronary artery ectasia in patients with stable angina pectoris

Buğra ÖZKAN
Özcan ÖRSÇELİK
Hatice YILDIRIM YAROĞLU
Senay BALCI
Mert Koray ÖZCAN
Ahmet ÇELİK
İsmail Türkay ÖZCAN
Pages
250–255
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

The isolated CAE group also exhibited a significantly higher mean platelet volume than that in the control group (10.75 fL and 10.17 fL, respectively, p=0.011).Conclusion: Our results show that there is an association between low serum adropin level and isolated CAE. (Anatol J Cardiol 2019; 22: 250-5)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Dilation of one or more coronary artery segments to a diameter at least 1.5 times that of a normal adjacent segment is referred to as coronary artery ectasia (CAE).
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Key Findings & Data:The aim of this study was to investigate the association between serum adropin levels and isolated CAE.Methods: Patients with stable angina pectoris who underwent coronary angiography (CAG) between August 2017 and July 2018 were evaluated prospectively.
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Conclusion & Impact:The isolated CAE group also exhibited a significantly higher mean platelet volume than that in the control group (10.75 fL and 10.17 fL, respectively, p=0.011).Conclusion: Our results show that there is an association between low serum adropin level and isolated CAE. (Anatol J Cardiol 2019; 22: 250-5)
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Özet

Objective: Dilation of one or more coronary artery segments to a diameter at least 1.5 times that of a normal adjacent segment is referred to as coronary artery ectasia (CAE). Adropin is a protein involved in endothelial function and is shown to have a protective effect on the regulation of cardiac functions. Atherosclerosis and endothelial dysfunction play an important role in the development of CAE. The aim of this study was to investigate the association between serum adropin levels and isolated CAE.Methods: Patients with stable angina pectoris who underwent coronary angiography (CAG) between August 2017 and July 2018 were evaluated prospectively. A total of 92 subjects were included in the study-40 patients over 18 years old and diagnosed with isolated CAE based on CAG findings and a control group of 52 patients.Results: Serum adropin level was found to be significantly lower in the isolated CAE group compared to the control group (1019.57 pg/mL and 1151.10 pg/mL, respectively, p=0.010). The isolated CAE group also exhibited a significantly higher mean platelet volume than that in the control group (10.75 fL and 10.17 fL, respectively, p=0.011).Conclusion: Our results show that there is an association between low serum adropin level and isolated CAE. (Anatol J Cardiol 2019; 22: 250-5)

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Cite This Article

ÖZKAN, B., ÖRSÇELİK, Ö., YAROĞLU, H. Y., BALCI, S., ÖZCAN, M. K., ÇELİK, A., ÖZCAN, İ. T. (2019). Association between serum adropin levels and isolated coronary artery ectasia in patients with stable angina pectoris. The Anatolian Journal of Cardiology, Cilt: 22 - Sayı: 5, 250–255. https://ajindex.com/articles/365728

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