Valve-sparing aortic root replacement in Loeys-Dietz syndrome and a novel mutation in TGFBR2

References (1)

1. Renard M, Callewaert B, Malfait F, Campens L, Sharif S, del Campo M, et al. Thoracic aortic-aneurysm and dissection in association with significant mitral valve disease caused by mutations in TGFB2. Int J Cardiol 2013; 165: 584-7. [CrossRef] van de Laar IM, Oldenburg RA, Pals G, Roos-Hesselink JW, de Graaf BM, Verhagen JM, et al. Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis. Nat Genet 2011; 43: 121-6. [CrossRef] Patel ND, Crawford T, Magruder JT, Alejo DE, Hibino N, Black J, et al. Cardiovascular operations for Loeys-Dietz syndrome:Intermediate term results. J Thorac Cardiovasc Surg 2017; 153: 406-12. [CrossRef] Patel ND, Alejo D, Crawford T, Hibino N, Dietz HC, Cameron DE, et al. Aortic Root Replacement for Children With Loeys-Dietz Syndrome. Ann Thorac Surg 2017; 103: 1513-8. [CrossRef] MacCarrick G, Black JH 3rd, Bowdin S, El-Hamamsy I, FrischmeyerGuerrerio PA, Guerrerio AL, et al. Loeys-Dietz syndrome: a primer for diagnosis and management. Genet Med 2014; 16: 576-87. [CrossRef] Loeys BL, Schwarze U, Holm T, Callewaert BL, Thomas GH, Pannu H, et al. Aneurysm syndromes caused by mutations in the TGF-beta receptor. N Engl J Med 2006; 355: 788-98. [CrossRef]