Journals / The Anatolian Journal of Cardiology / 2017 / Cilt: 17 - Sayı: 4

Clinical risk scores predict procedural complications of primary percutaneous coronary intervention

Pages
276–284
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Pre-interventional assessment of these scores may help the interventional cardiologist to prepare for procedural complications during pPCI

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The predictive value of five risk score models containing clinical (PAMI-PMS, GRACE–GRS, and modified ACEF-ACEFm–scores), angiographic SYNTAX score (SXS) and combined Clinical SYNTAX score (CSS) variables were evaluated for the incidence of three procedural complications of primary percutaneous coronary intervention (pPCI): iatrogenic coronary artery dissection, angiographically visible distal embolization and angiographic no-reflow phenomenon.Methods: The mentioned scores and the incidence of procedural complications were retrospectively analyzed in 399 consecutive patients with acute ST-elevation myocardial infarction who underwent pPCI.Results: Coronary dissection, distal embolization and no-reflow occurred in 39 (9.77%), 71 (17.79%), and 108 (27.07%) subjects, respectively.
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Key Findings & Data:Coronary dissections were significantly associated with higher GRS, ACEFm, and CSS values (all p<0.05).
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Conclusion & Impact:Pre-interventional assessment of these scores may help the interventional cardiologist to prepare for procedural complications during pPCI
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The predictive value of five risk score models containing clinical (PAMI-PMS, GRACE–GRS, and modified ACEF-ACEFm–scores), angiographic SYNTAX score (SXS) and combined Clinical SYNTAX score (CSS) variables were evaluated for the incidence of three procedural complications of primary percutaneous coronary intervention (pPCI): iatrogenic coronary artery dissection, angiographically visible distal embolization and angiographic no-reflow phenomenon.Methods: The mentioned scores and the incidence of procedural complications were retrospectively analyzed in 399 consecutive patients with acute ST-elevation myocardial infarction who underwent pPCI.Results: Coronary dissection, distal embolization and no-reflow occurred in 39 (9.77%), 71 (17.79%), and 108 (27.07%) subjects, respectively. Coronary dissections were significantly associated with higher GRS, ACEFm, and CSS values (all p<0.05). PMS, GRS, ACEFm, and CSS were significantly higher in patients with no-reflow (all p<0.05), while distal embolization was not predicted by any of the calculated scores. In multiple logistic regression models, GRS and ACEFm remained independent predictors of both coronary dissections (OR 3.20, 95% CI 1.56–6.54, p<0.01 and OR 2.87, 95% CI 1.27–6.45, p=0.01, respectively) and no-reflow (OR 1.71, 95% CI 1.04–2.82, p=0.03 and OR 1.86, 95% CI 1.10–3.14, p=0.01, respectively).Conclusion: Whereas SXS failed to predict procedural complications related to pPCI, two simple, noninvasive risk models, GRS and ACEFm, independently predicted coronary dissections and no-reflow. Pre-interventional assessment of these scores may help the interventional cardiologist to prepare for procedural complications during pPCI

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Cite This Article

SCRİDON, A., SUS, I., SERBAN, R. C., HADADİ, L. *., LAKATOS, É. K., DEMJÉN, Z., DOBREANU, D. (2017). Clinical risk scores predict procedural complications of primary percutaneous coronary intervention. The Anatolian Journal of Cardiology, Cilt: 17 - Sayı: 4, 276–284. https://ajindex.com/articles/365307

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