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Journals / The Anatolian Journal of Cardiology / 2018 / Cilt: 19 - Sayı: 2

MicroRNAs in acute myocardial infarction: Evident value as novel biomarkers?

Zhongxiu CHEN
Chen Lİ
Ke LİN
Qing ZHANG
Yucheng CHEN
Li RAO
Pages
140–147
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This manuscript will highlight the recentupdates regarding the involvement of miRs as biomarkers in AMI and emphasize their value in vulnerable atherosclerotic plaque prediction andmonitoring of platelet activation.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Traditional circulating biomarkers play a fundamental role in the diagnosis and prognosis of acute myocardial infarction (AMI).
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Key Findings & Data:Due to their significant roles in disease development, they can be used as biomarkers.
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Conclusion & Impact:This manuscript will highlight the recentupdates regarding the involvement of miRs as biomarkers in AMI and emphasize their value in vulnerable atherosclerotic plaque prediction andmonitoring of platelet activation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Traditional circulating biomarkers play a fundamental role in the diagnosis and prognosis of acute myocardial infarction (AMI). However, theyhave several limitations. microRNAs (miRs), a class of RNA molecules that do not encode proteins, function directly at the RNA level by inhibitingthe translation of messenger RNAs. Due to their significant roles in disease development, they can be used as biomarkers. Accumulating evidencehas revealed an attractive role of miRs as biomarkers of AMI and its associated symptoms, including vulnerable atherosclerotic plaques,and their role in disease diagnosis, platelet activation monitoring, and prognostic outcome prediction. This manuscript will highlight the recentupdates regarding the involvement of miRs as biomarkers in AMI and emphasize their value in vulnerable atherosclerotic plaque prediction andmonitoring of platelet activation.

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Cite This Article

CHEN, Z., Lİ, C., LİN, K., ZHANG, Q., CHEN, Y., RAO, L. (2018). MicroRNAs in acute myocardial infarction: Evident value as novel biomarkers?. The Anatolian Journal of Cardiology, Cilt: 19 - Sayı: 2, 140–147. https://ajindex.com/articles/365242

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