Journals / The Anatolian Journal of Cardiology / 2021 / Cilt: 25 - Sayı: 7

Is the increase in eltrombopag dose cause of myocardial infarction?

Pages
520–521
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, we present a patient with ITP who developed recurrent myocardial infarction and intense thrombus in the stent after increasing the eltrombopag dose.

📌 3 Key Takeaways

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Objective & Hypothesis:Immune thrombocytopenia (ITP) is an acquired disorder caused by immune-mediated attack, enhanced clearance, and insufficient compensatory production of platelets.
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Key Findings & Data:Historically, ITP treatment strategies have suppressed platelet destruction with glucocorticoids, intravenous immune globulin (IVIG), cytotoxic agents, and splenectomy (1).
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Conclusion & Impact:In this study, we present a patient with ITP who developed recurrent myocardial infarction and intense thrombus in the stent after increasing the eltrombopag dose.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Immune thrombocytopenia (ITP) is an acquired disorder caused by immune-mediated attack, enhanced clearance, and insufficient compensatory production of platelets. Historically, ITP treatment strategies have suppressed platelet destruction with glucocorticoids, intravenous immune globulin (IVIG), cytotoxic agents, and splenectomy (1). Eltrombopag is an oral nonpeptide thrombopoietin receptor agonist (TPO-RA) approved for use in several countries for the treatment of ITP with insufficient response to corticosteroids, immunoglobulins, or splenectomy. In this study, we present a patient with ITP who developed recurrent myocardial infarction and intense thrombus in the stent after increasing the eltrombopag dose.

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Cite This Article

ÖZGÜNOĞLU, E. C., BAYAR, N., ARSLAN, Ş., ERSOYSAL, M. R., AVCI, R. (2021). Is the increase in eltrombopag dose cause of myocardial infarction?. The Anatolian Journal of Cardiology, Cilt: 25 - Sayı: 7, 520–521. https://ajindex.com/articles/365137

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References (1)

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