Journals / Şişli Etfal Hastanesi Tıp Bülteni / 2010 / Cilt: 44 - Sayı: 2

Use of desflurane and sevoflurane for elective caesarean section: Maternal and neonatal effects

Desfluran ve sevofluranın elektif sezaryen operasyonlarında kullanımı: Anne ve yenidoğan üzerindeki etkileri

Pages
66–71
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: We concluded that; the maternal and newborn effects of desflurane and sevoflurane were similar, and desflurane can be preferred to sevoflurane with the conditions for early extubation and short recovery period in elective caesarean operations in the concentrations that we have used.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In our study we aimed to compare the maternal and neonatal effects of desflurane and sevoflurane in women undergoing elective caesarean section.
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Key Findings & Data:Methods: After the approval from Ethics Committee of our Hospital, 40 healthy parturients undergoing elective caserean section were allocated randomly into two groups after their informed consent was taken.
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Conclusion & Impact:Conclusion: We concluded that; the maternal and newborn effects of desflurane and sevoflurane were similar, and desflurane can be preferred to sevoflurane with the conditions for early extubation and short recovery period in elective caesarean operations in the concentrations that we have used.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In our study we aimed to compare the maternal and neonatal effects of desflurane and sevoflurane in women undergoing elective caesarean section. Methods: After the approval from Ethics Committee of our Hospital, 40 healthy parturients undergoing elective caserean section were allocated randomly into two groups after their informed consent was taken. Desflurane 3% in Group D or sevoflurane 1% in Group S were used in a 50% nitrous oxide and oxygen mixture for maintenance of anaesthesia. Systolic, diastolic, mean blood pressure, heart rate values and peripheral oxygen saturation were recorded as baseline and followed up with 5 min intervals peroperatively. Neonatal status was evaluated with APGAR scores at 1 and 5 min, umblical cord blood gas analysis, neurologic adaptive capacity scores at 2 and 24 h. Extubation and recovery times of the mother, haemoglobin and haematocrit values were recorded preoperatively and at postoperative 24.hours. Results: Blood pressure and heart rate changes were similar in Group D and Group S in intraoperative period. Neonatal outcome was evaluated similar in Group D and Group S. Extubation and recovery times were shorter in Group D than Group S. Haemoglobin and haematocrit values were similar between the groups preoperatively and at postoperative 24 hours. Conclusion: We concluded that; the maternal and newborn effects of desflurane and sevoflurane were similar, and desflurane can be preferred to sevoflurane with the conditions for early extubation and short recovery period in elective caesarean operations in the concentrations that we have used.

Özet

Amaç: Çalışmamızda elektif sezaryen operasyonlarında sevofluran ve desfluranın anne ve yenidoğan üzerindeki etkilerinin karşılaştırılması amaçlandı. Yöntem: Hastanemiz Etik Kurulu onayı ile genel anestezi altında sezaryen operasyonu planlanan 40 sağlıklı gebe, bilgilendirilmiş onamları alındıktan sonra rasgele iki gruba ayrıldı. Anestezi idamesinde %50 nitröz oksit ve oksijen karışımı içinde Grup D’de %3 desfluran; Grup S’de %1 sevofluran kullanıldı. Sistolik, diastolik, ortalama kan basınçları, kalp atım hızı ve periferik oksijen satürasyonu başlangıçta ve peroperatif 5 dk aralıklarla kaydedildi. Yenidoğanda 1 ve 5. dk APGAR skorları, umblikal kord kan gazları ile 2. ve 24. saat nörolojik adaptif kapasite skorları değerlendirildi. Annenin ekstübasyon ve derlenme süreleri ile preoperatif ve postoperatif 24. saat hemoglobin ve hematokrit değerleri kaydedildi. Bulgular: Grup D ve Grup S’de kan basıncı ve kalp hızı değişiklikleri intraoperatif dönemde benzer bulundu. Neonatal veriler Grup D ve Grup S’de benzer olarak değerlendirildi. Ekstübasyon ve derlenme süreleri Grup D’de Grup S’e göre anlamlı olarak kısa bulundu. Grupların preoperatif ve postoperatif hemoglobin ve hematokrit değerleri benzerdi. Sonuç: Çalışmamızda elektif sezaryen operasyonlarında uyguladığımız konsantrasyonlarda desfluran ve sevofluranın anne ve yenidoğanda etkilerinin benzer olduğu, desfluranın erken ekstübasyon ve kısa derlenme süresi ile sevoflurana göre daha çok tercih edilebileceği sonucuna vardık.

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Cite This Article

BURGUTOĞLU, A. B., EKŞİOĞLU, B., SİVRİKAYA, G. U., EROL, M. K., HANCI, A. (2010). Use of desflurane and sevoflurane for elective caesarean section: Maternal and neonatal effects. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 44 - Sayı: 2, 66–71. https://ajindex.com/articles/364166

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