Journals / Şişli Etfal Hastanesi Tıp Bülteni / 2005 / Cilt: 39 - Sayı: 1

Determination of reference values in the individuals living Edirne and neighborhood region: Plasma lipid profile

Edirne ve çevresinde yaşayan bireylerde referans aralıklarının belirlenmesi: Plazma lipid profili

Pages
24–31
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Finding of both the high plasma triglyceride, LDL and total cholesterol that were found to be directly associated with increased risk of developing coronary artery diseases and low HDL cholesterol levels that also reported to have a protective role on these conditions may indicate that the regional population might be sensitive for developing coronary artery disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To determine the reference intervals for triglyceride, LDL, HDL kind total cholesterol in the individuals living Edirne and neighborhood region and therefore, to present any possible risk factors to face with for the development öf coronary artery diseases which were associated with hyperliidemia in these population.
📊
Key Findings & Data:Although triglyceride levels were higher in men when they were compared to women, LDL, HDL and total cholesterol levels were found to be higher in women (p<().00l).
💡
Conclusion & Impact:Conclusion: Finding of both the high plasma triglyceride, LDL and total cholesterol that were found to be directly associated with increased risk of developing coronary artery diseases and low HDL cholesterol levels that also reported to have a protective role on these conditions may indicate that the regional population might be sensitive for developing coronary artery disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Lipoproteinler · LDL · Trigliseridler

Abstract

Objective: To determine the reference intervals for triglyceride, LDL, HDL kind total cholesterol in the individuals living Edirne and neighborhood region and therefore, to present any possible risk factors to face with for the development öf coronary artery diseases which were associated with hyperliidemia in these population. Study Design: Patients, born and lived in Edirne, Kırklareli and Tekirdağ, applied to Hospital, of Trakya University Faculty of Medicine included in this study and their plasma triglyceride, LDL, HDL and total cholesterol levels were determined. Obtained data were istatistically treated to establish the regional reference values. Results: The mean plasma triglyceride, LDL, HDL and total cholesterol levels were determined for all the age groups. Although triglyceride levels were higher in men when they were compared to women, LDL, HDL and total cholesterol levels were found to be higher in women (p<().00l). Conclusion: Finding of both the high plasma triglyceride, LDL and total cholesterol that were found to be directly associated with increased risk of developing coronary artery diseases and low HDL cholesterol levels that also reported to have a protective role on these conditions may indicate that the regional population might be sensitive for developing coronary artery disease.

Özet

Amaç: Edirne ve çevresinde ypşayan bireylerin trigliserid, LDL, HDL ve total kolesterol referans değerlerinin belirlenerek, yöre insanının hiperlipidemi ile yakından ilişkili olan aterosklerotik kalp damar hastalıkları açısından potansiyel risk tablosunu ortaya koymaktır. Gereç ve Yöntem: Trakya Üniversitesi Tıp Fakültesi Hastanesi'ne başvuran ve doğum yeri Edirne; Kırklareli ve Tekirdağ olan hastaların plazma trigliserid, LDL, HDL ve total kolesterol düzeyleri istatistiksel olarak değerlendirilmiş ve yöremize ait plazma lipid profili belirlenmişti. Bulgular: Tüm yaş grupları için ortalama trigliserid, LDL, HDL ve total kolesterol değerleri bulunmuştur. Trigliserid düzeyleri erkeklerde kadınlara göre, total kolesterol, LDL ve HDL kolesterol düzeyleri kadınlarda erkeklere göre daha yüksek bulunmuştur (p<0.001). Sonuçlar: Edirne ve çevre illerinde yaşayan bireylerde aterosklerotik kalp hastalıkları yönünden direk ilişkili Olan plazma trigliserid, LDL ve total kolesterol düzeyleri oldukça yüksek, bu hastalıklara karşı koruyucu bir faktör olarak gösterilen HDL kolesterol değerlerinin düşük bulunması, yöremiz insanının bu hastalıklara karşı oldukça duyarlı olabileceğinin bir göstergesidir

🔖

Cite This Article

ERBAŞ, H., DEMİRKIRAN, S., GÜLEN, Ş. (2005). Determination of reference values in the individuals living Edirne and neighborhood region: Plasma lipid profile. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 39 - Sayı: 1, 24–31. https://ajindex.com/articles/364117

References (12)

  1. Solberg HE: Establishment unci use of reference values. In: Burtis CA, Ashwood ER, Tietz NW, (cd.) Tietz, Textbook of Clinical Chemistry, Philadelphia: W.B. Saunders Company; 1999, 336-356
  2. International Federation of Clinical Chemistry expert panel on theory of reference values: Part 2. Selection of individuals for the production of reference values. J Clin Chem Clin Biochem; 25:639-644, 1987
  3. Holmes EW, Kalın SE, Molnar PE and Bermes EW: Veri¬fication of reference ranges by using a Monte Carlo sampling technique. Clin Chem, 40:2216-2222, 1994
  4. Medicare, Medicaid and CLIA programs; regulations implementing the Clinical Laboratory Improvement Amendments of 1988 (CLIA)-HCFA. Final rule with comment period. Fed Regist, 57:7002-7186, 1992
  5. Komi T, Kairisto V, Virtanen A, Uusipaikka E, Rajamaki A, Fiiernan H, Juva K, Koivula T and Nantö V: Reference intervals developed from data for hospitalized patients. Computerized method based on combination of labora¬tory and diagnostic data. Clin Chem, 40:2209-2215, 1994
  6. Soldin SJ, Murtlıy JN. Agarwalla PK, Ojeifo O, Chea J: Pediatric reference ranges for creatine kinase, CKMB, troponin ı, iron, and Cortisol. Clin Biochem, 32:77-80, 1999
  7. Solberg HE: Using hospitalized population to establish reference intervals. Pros, and Cons. Clin Chem, 40:2205- 2206. 1994
  8. Solberg HE: RefVa]: a program implementing the recom mendations of the international Federation of Clinical Chemistry on the statistical treatment of reference values. Computer Methods and Programs in Biomedicine, 48:247-256, 1995
  9. Internationa] Federation of Clinical Chemistry expert panel on the theory of reference values: Part 5. Statistical treatment of collected reference values: determination of reference limits. J Clin Chem Clin Biochem, 25:645-656. 1987
  10. Mahley RW, Pahtoğlu ICE, Alak 2, Pepin JD, Langlois AM, Cheung V, Onal H, Fulka P, Mahley LL, Vakar F, Özbayrakçı S, Gökdemir O, Winkler W: Turk isli heart study: lipids, lipoproteins and apolipoproteins. J Lipid Research, 36:839-856, 1995
  11. Lüttmann SA, von Eckardstein W, Wei H, Funke E, Kölı- ler R, Mahley W, Ass man n G: Electrophoretie screening for genetic variation in apolipoprotein C-II1: identificati¬on of a novel apoC III variant, apoC-HI (Asp45 Asn), in a Turkish patient. J Lipid Res, 35:1431-1440, 1994
  12. Oezcueruemez MP, Bilgin Y, Wollny M, Gediz A, Arat A, Karatay E, Akinci A, Sinterhauf K, Koch H, Siegfried I, von Georgi R, Brenner G, Kîoer HU: Prevalaııce