SavedAdd your journal

Journals / Şişli Etfal Hastanesi Tıp Bülteni / 2012 / Cilt: 46 - Sayı: 1

Octreotide treatment in neonatal chylothorax: a case report

Yenidoğan şilotoraks tedavisinde oktreotid kullanımı: Olgu sunumu

Muhittin ÇELİK
Ali BÜLBÜL
Sinan USLU
Nihat SEVER
EMRAH CAN
Pages
26–29
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A neonate who developed chylothorax after congenital diaphragmatic hernia operation and who was successfully treated with octreotide after failure of conservative treatment is presented in this case report.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Chylothorax is defined as accumulation of chylous fluid in pleural cavity which may be caused by congenital and acquired diseases.
📊
Key Findings & Data:During neonatal period, chylothorax treatment is composed of conservative( pleural drainage, termination of enteral feeding, total parenteral nutrition and supplementation with medium-chain triglycerides) and surgical therapies(ductus thoracicus ligation, pleuredesis).
💡
Conclusion & Impact:A neonate who developed chylothorax after congenital diaphragmatic hernia operation and who was successfully treated with octreotide after failure of conservative treatment is presented in this case report.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Chylothorax is defined as accumulation of chylous fluid in pleural cavity which may be caused by congenital and acquired diseases. During neonatal period, chylothorax treatment is composed of conservative( pleural drainage, termination of enteral feeding, total parenteral nutrition and supplementation with medium-chain triglycerides) and surgical therapies(ductus thoracicus ligation, pleuredesis). Nowadays, for cases among which conservative therapies fail, treatment with octreotide has been reported to be beneficial with promising results. A neonate who developed chylothorax after congenital diaphragmatic hernia operation and who was successfully treated with octreotide after failure of conservative treatment is presented in this case report.

Özet

Şilotoraks; konjenital veya edinsel nedenlerle, plevral boşlukta şilöz mayi birikimidir. Yenidoğan döneminde şilotoraks tedavisinde konservatif yaklaşımlar (plevral drenaj, enteral beslenmenin kesilmesi, total parenteral nutrisyon, orta zincirli trigliserid ile beslenme) ve cerrahi yöntemler (duktus torasikus ligasyonu, pleuro-peritoneal şant veya plörodesis) kullanılmaktadır. Günümüzde konservatif yaklaşımlarla sonuç alınamayan olgularda, oktreotid tedavisi ile başarılı sonuçlar alındığı bildirilmektedir. Bu yazıda, yenidoğan döneminde konjenital diyafragma hernisi operasyonu sonrası şilotoraks gelişen, konservatif yöntemlerle yanıt alınamayan, oktreotid verilerek başarıyla tedavi edilen bir olgu sunuldu.

🔖

Cite This Article

ÇELİK, M., BÜLBÜL, A., USLU, S., SEVER, N., CAN, E. (2012). Octreotide treatment in neonatal chylothorax: a case report. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 46 - Sayı: 1, 26–29. https://ajindex.com/articles/364081

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Migliori C, Boroni G, Milianti S, Ekema G. Chylothorax. Minerva Pediatr. 2010;62:89-91
  2. Das A, Shah PS. Octreotide for the treatment of chylothorax in neonates. Cochrane Database Syst Rev.2010;(9):CD006388
  3. Paramés F, Freitas I, Fragata J, Trigo C, Pinto MF. Octreotide-- additional conservative therapy for postoperative chylothorax in congenital heart disease. Rev Port Cardiol. 2009;28(7-8):799- 807
  4. Waag KL, Loff S, Zahn K et al. Congenital diaphragmatic hernia: a modern day approach. Semin Pediatr Surg. 2008;17(4):244–54
  5. Kavvadia V, Greenough A, Davenport M, Karani J, Nicolaides KH. Chylothorax after repair of congenital diaphragmatic hernia—risk factors and morbidity. J Pediatr Surg. 1998;33(3):500–02
  6. Zavala A, Campos JM, Riutort C, Skorin I, Godoy L, Faunes M, Kattan J. Chylothorax in congenital diaphragmatic hernia. Pediatr Surg Int. 2010;26(9):919–22
  7. Moreira-Pinto J, Rocha P, Osório A, Bonet B, Carvalho F, Duarte C, Oliveira L. Octreotide in the treatment of neonatal postoperative chylothorax: report of three cases and literature review. 2010. DOI: 10.1007/s00383-010-2730-2 8. Bulbul A, Okan F, Nuhoglu A. Idiopathic congenital chylothorax presented with severe hydrops and treated with octreotide in term newborn. J Matern Fetal Neonatal Med. 2009;22(12):1197-2000
  8. Roehr CC, Jung A, Proquitté H, Blankenstein O, Hammer H, Lakhoo K, Wauer RR. Somatostatin or octreotide as treatment options for chylothorax in young children: a systematic review. Intensive Care Med. 2006;32(5):650-57
  9. Mohseni-Bod H, Macrae D, Slavik Z. Somatostatin analog (octreotide) in management of neonatal postoperative chylothorax: is it safe? Pediatr Crit Care Med.2004;5(4):356–57
  10. Goyal A, Smith NP, Jesudason EC, Kerr S, Losty PD. Octreotide for treatment of chylothorax after repair of congenital diaphragmatic hernia. J Pediatr Surg. 2003;38(8):19-2
  11. Buettiker V, Hug MI, Burger R, Baenziger O. Somatostatin: a new therapeutic option for the treatment of chylothorax. Intensive Care Med. 2001;27(6):1083–86
  12. Gonzalez R, Bryner BS, Teitelbaum DH, Hirschl RB, Drongowski RA, Mychaliska GB. Chylothorax after congenital diaphragmatic hernia repair. J Pediatr Surg. 2009;44(6):1181-85
  13. Copons Fernández C, Benîtez Segura I, Castillo Salinas F, Salcedo Abizanda S. Neonatal chylothorax: aetiology, clinical course and efficacy of treatment. An Pediatr. 2008;68(3):224–31.