Journals / Şişli Etfal Hastanesi Tıp Bülteni / 2014 / Cilt: 48 - Sayı: 4

Maternal Thyroid Functions in Pre-Eclampsia

Preeklampside maternal tiroid fonksiyonları

Pages
308–311
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, the identification of thyroid hormone in pregnancy can not help obstetricians to predict the occurrence of pre-eclampsia.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, we aimed to evaluate the relationship between pre-eclampsia and thyroid profile.
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Key Findings & Data:Material and Method: In this case control study, serum concentrations of thyroid-stimulating hormone (TSH), free triiodothyronine (FT3) and free thyroxine (FT4) were prospectively measured in fifty preeclamptic patients compared with thirty normotensive pregnant controls before labor.
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Conclusion & Impact:Therefore, the identification of thyroid hormone in pregnancy can not help obstetricians to predict the occurrence of pre-eclampsia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, we aimed to evaluate the relationship between pre-eclampsia and thyroid profile. Material and Method: In this case control study, serum concentrations of thyroid-stimulating hormone (TSH), free triiodothyronine (FT3) and free thyroxine (FT4) were prospectively measured in fifty preeclamptic patients compared with thirty normotensive pregnant controls before labor. Both groups were composed of various pregnant females in the third trimester. Two groups were also compared with regard to obstetrical outcomes.Results: Levels of TSH, FT3 and FT4 showed no significant difference between the pre-eclamptic group and normotensive controls. Regarding obstetrical outcomes; the difference was found to be significant for gestational age when studying labor and birth-weight between two groups. Preeclamptic patients delivered at earlier gestation and had lower infant birth-weights compared with normotensive controls. Also, we did not find any statistically significant correlation between thyroid function and birth-weight in both groups. Conclusion: Our findings suggest that thyroid function does not change in pre-eclampsia. Therefore, the identification of thyroid hormone in pregnancy can not help obstetricians to predict the occurrence of pre-eclampsia.

Özet

Amaç: Çalışmamızda, preeklampsi ile tiroid hormonları arasındaki ilişkiyi incelemeyi amaçladık.Gereç ve Yöntem: Bu çalışmada, serum tiroid stimule edici hormon (TSH), serbest triiodotironin (FT3) ve serbest tiroksin düzeyleri (FT4) 50 preeklamptik gebe ve 30 normotansif gebede doğumdan önce prospektif olarak ölçüldü. Her iki grup da 3. trimesterdeki gebelerden oluşmaktaydı. Gruplar tiroid hormonları ve obstetrik sonuçlar açısından karşılaştırıldı.Bulgular: Serum TSH, FT3 ve FT4 düzeyleri açısından iki grup arasında anlamlı bir fark saptanmadı. Ancak, doğum haftası ve doğum ağırlığı açısından her iki grup arasındaki fark istatistiksel olarak anlamlıydı. Normotansif kontroller ile karşılaştırıldığında, preeklamptik hastalar daha erken gebelik haftasında doğurdular ve bu grupta, yenidoğan doğum ağırlığı daha düşüktü. Diğer yandan, iki grupta da, tiroid fonksiyonları ve doğum ağırlığı arasında anlamlı korelasyon saptanmadı.Sonuç: Bulgularımız, tiroid fonksiyonlarının preeklampside değişmediğini göstermektedir. Bu nedenle gebelikte tiroid hormonlarının preeklampsiyi ön görmede kadın doğum hekimlerine yardımcı olamayacağı kanısındayız.

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Cite This Article

NAYKI, Ü. A., NAYKI, C., ULUĞ, P., ÖNER, G., YILDIRIM, Y., TANER, C. E. (2014). Maternal Thyroid Functions in Pre-Eclampsia. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 48 - Sayı: 4, 308–311. https://ajindex.com/articles/363980

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